Molecular basis of the alternative recruitment of GABAA versus glycine receptors through gephyrin

GABAAreceptors and plasticity of inhibitory neurotransmission in the central nervous system

(2014) Jean-Marc Fritschy et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Gephyrin: a master regulator of neuronal function?

(2014) Shiva K. Tyagarajan et al.   NATURE REVIEWS NEUROSCIENCE

Palmitoylation of Gephyrin Controls Receptor Clustering and Plasticity of GABAergic Synapses

(2014) Borislav Dejanovic et al.   PLOS BIOLOGY

Mixed miniature postsynaptic currents resulting from co-release of glycine and GABA recorded from glycinergic neurons in the neonatal respiratory network

(2013) Jamilur Rahman et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Extracellular Signal-regulated Kinase and Glycogen Synthase Kinase 3β Regulate Gephyrin Postsynaptic Aggregation and GABAergic Synaptic Function in a Calpain-dependent Mechanism

(2013) Shiva K. Tyagarajan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Quantitative Nanoscopy of Inhibitory Synapses: Counting Gephyrin Molecules and Receptor Binding Sites

(2013) Christian G. Specht et al.   NEURON

Ligand binding by PDZ domains

(2012) Celestine N. Chi et al.   BIOFACTORS

Homeostatic Regulation of Gephyrin Scaffolds and Synaptic Strength at Mature Hippocampal GABAergic Postsynapses†

(2012) Andreas Vlachos et al.   CEREBRAL CORTEX

Direct binding of GABAAreceptor β2 and β3 subunits to gephyrin

(2012) Sarah Kowalczyk et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

γ-Aminobutyric Acid Type A (GABAA) Receptor α Subunits Play a Direct Role in SynapticVersusExtrasynaptic Targeting

(2012) Xia Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Splice-specific Glycine Receptor Binding, Folding, and Phosphorylation of the Scaffolding Protein Gephyrin

(2012) Jens Herweg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation of Gephyrin in Hippocampal Neurons by Cyclin-dependent Kinase CDK5 at Ser-270 Is Dependent on Collybistin

(2012) Jochen Kuhse et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

To serve and neuroprotect

(2012) Elie Dolgin   NATURE MEDICINE

Can PSD95 inhibitors widen the therapeutic window?

(2012) Alexandra Flemming   NATURE REVIEWS DRUG DISCOVERY

A high-affinity, dimeric inhibitor of PSD-95 bivalently interacts with PDZ1-2 and protects against ischemic brain damage

(2012) A. Bach et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gephyrin, the enigmatic organizer at GABAergic synapses

(2012) Verena Tretter et al.   Frontiers in Cellular Neuroscience

iMOSFLM: a new graphical interface for diffraction-image processing withMOSFLM

(2011) T. Geoff G. Battye et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Functional regulation of GABAA receptors in nervous system pathologies

(2011) Rochelle M Hines et al.   CURRENT OPINION IN NEUROBIOLOGY

Regulation of glycine receptor diffusion properties and gephyrin interactions by protein kinase C

(2011) Christian G Specht et al.   EMBO JOURNAL

Differential localization of GABAA receptor subunits in relation to rat striatopallidal and pallidopallidal synapses

(2011) A. Gross et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Molecular Basis of the γ-Aminobutyric Acid A Receptor α3 Subunit Interaction with the Clustering Protein Gephyrin

(2011) Verena Tretter et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gephyrin-mediated γ-Aminobutyric Acid Type A and Glycine Receptor Clustering Relies on a Common Binding Site

(2011) Hans-Michael Maric et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cell-Permeable and Plasma-Stable Peptidomimetic Inhibitors of the Postsynaptic Density-95/N-Methyl-d-Aspartate Receptor Interaction

(2011) Anders Bach et al.   JOURNAL OF MEDICINAL CHEMISTRY

The Residence Time of GABAARs at Inhibitory Synapses Is Determined by Direct Binding of the Receptor  1 Subunit to Gephyrin

(2011) J. Mukherjee et al.   JOURNAL OF NEUROSCIENCE

Phosphoproteomic Profiling of In Vivo Signaling in Liver by the Mammalian Target of Rapamycin Complex 1 (mTORC1)

(2011) Gokhan Demirkan et al.   PLoS One

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Modulation of Shank3 PDZ Domain Ligand-Binding Affinity by Dimerization

(2010) Wendy S. Iskenderian-Epps et al.   CHEMBIOCHEM

Biomimetic divalent ligands for the acute disruption of synaptic AMPAR stabilization

(2010) Matthieu Sainlos et al.   Nature Chemical Biology

Calorie restriction alters mitochondrial protein acetylation

(2009) Bjoern Schwer et al.   AGING CELL

Design and Synthesis of Highly Potent and Plasma-Stable Dimeric Inhibitors of the PSD-95-NMDA Receptor Interaction

(2009) Anders Bach et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions

(2009) C. Choudhary et al.   SCIENCE

Modified Peptides as Potent Inhibitors of the Postsynaptic Density-95/N-Methyl-d-Aspartate Receptor Interaction

(2008) Anders Bach et al.   JOURNAL OF MEDICINAL CHEMISTRY

The Clustering of GABAA Receptor Subtypes at Inhibitory Synapses is Facilitated via the Direct Binding of Receptor  2 Subunits to Gephyrin

(2008) V. Tretter et al.   JOURNAL OF NEUROSCIENCE

Neural palmitoyl-proteomics reveals dynamic synaptic palmitoylation

(2008) Rujun Kang et al.   NATURE

Normal sleep homeostasis and lack of epilepsy phenotype in GABAA receptor α3 subunit-knockout mice

(2008) R. Winsky-Sommerer et al.   NEUROSCIENCE

Large-Scale Identification and Evolution Indexing of Tyrosine Phosphorylation Sites from Murine Brain

(2007) Bryan A. Ballif et al.   JOURNAL OF PROTEOME RESEARCH

Hydrophobic Interactions Mediate Binding of the Glycine Receptor β-Subunit to Gephyrin

(2003) Matthias Kneussel et al.   JOURNAL OF NEUROCHEMISTRY