Changing the peptide specificity of a human T-cell receptor by directed evolution
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Changing the peptide specificity of a human T-cell receptor by directed evolution
Authors
Keywords
-
Journal
Nature Communications
Volume 5, Issue 1, Pages -
Publisher
Springer Nature
Online
2014-11-07
DOI
10.1038/ncomms6223
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- T cell receptor bias for MHC: co-evolution or co-receptors?
- (2014) Sneha Rangarajan et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- TCR Scanning of Peptide/MHC through Complementary Matching of Receptor and Ligand Molecular Flexibility
- (2014) W. F. Hawse et al. JOURNAL OF IMMUNOLOGY
- Computational Design of the Affinity and Specificity of a Therapeutic T Cell Receptor
- (2014) Brian G. Pierce et al. PLoS Computational Biology
- T-cell Receptor Specificity Maintained by Altered Thermodynamics
- (2013) Florian Madura et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Plasticity in the Contribution of T Cell Receptor Variable Region Residues to Binding of Peptide–HLA-A2 Complexes
- (2013) Sheena N. Smith et al. JOURNAL OF MOLECULAR BIOLOGY
- The basis for limited specificity and MHC restriction in a T cell receptor interface
- (2013) Kurt H. Piepenbrink et al. Nature Communications
- Cutting Edge: Evidence for a Dynamically Driven T Cell Signaling Mechanism
- (2012) W. F. Hawse et al. JOURNAL OF IMMUNOLOGY
- Structural insights into the editing of germ-line-encoded interactions between T-cell receptor and MHC class II by V CDR3
- (2012) L. Deng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Epitope Flexibility and Dynamic Footprint Revealed by Molecular Dynamics of a pMHC-TCR Complex
- (2012) Cyril F. Reboul et al. PLoS Computational Biology
- TCRs Used in Cancer Gene Therapy Cross-React with MART-1/Melan-A Tumor Antigens via Distinct Mechanisms
- (2011) O. Y. Borbulevych et al. JOURNAL OF IMMUNOLOGY
- Disparate Degrees of Hypervariable Loop Flexibility Control T-Cell Receptor Cross-Reactivity, Specificity, and Binding Mechanism
- (2011) Daniel R. Scott et al. JOURNAL OF MOLECULAR BIOLOGY
- Structures of native and affinity-enhanced WT1 epitopes bound to HLA-A0201: Implications for WT1-based cancer therapeutics
- (2010) Oleg Y. Borbulevych et al. MOLECULAR IMMUNOLOGY
- RosettaBackrub--a web server for flexible backbone protein structure modeling and design
- (2010) F. Lauck et al. NUCLEIC ACIDS RESEARCH
- Hard wiring of T cell receptor specificity for the major histocompatibility complex is underpinned by TCR adaptability
- (2010) S. R. Burrows et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification and engineering of human variable regions that allow expression of stable single-chain T cell receptors
- (2010) D. H. Aggen et al. PROTEIN ENGINEERING DESIGN & SELECTION
- T Cell Receptor Cross-reactivity Directed by Antigen-Dependent Tuning of Peptide-MHC Molecular Flexibility
- (2009) Oleg Y. Borbulevych et al. IMMUNITY
- Germ Line-governed Recognition of a Cancer Epitope by an Immunodominant Human T-cell Receptor
- (2009) David K. Cole et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The molecular basis of TCR germline bias for MHC is surprisingly simple
- (2009) K Christopher Garcia et al. NATURE IMMUNOLOGY
- Evolutionarily Conserved Amino Acids That Control TCR-MHC Interaction
- (2008) Philippa Marrack et al. Annual Review of Immunology
- WT1 peptide vaccine for the treatment of cancer
- (2008) Yoshihiro Oka et al. CURRENT OPINION IN IMMUNOLOGY
- Backrub-Like Backbone Simulation Recapitulates Natural Protein Conformational Variability and Improves Mutant Side-Chain Prediction
- (2008) Colin A. Smith et al. JOURNAL OF MOLECULAR BIOLOGY
- Structural features of T cell receptor variable regions that enhance domain stability and enable expression as single-chain VαVβ fragments
- (2008) Sarah A. Richman et al. MOLECULAR IMMUNOLOGY
- Control of HIV-1 immune escape by CD8 T cells expressing enhanced T-cell receptor
- (2008) Angel Varela-Rohena et al. NATURE MEDICINE
- Structure-based design of a T-cell receptor leads to nearly 100-fold improvement in binding affinity for pepMHC
- (2008) Jaafar N. Haidar et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started