Identification and engineering of human variable regions that allow expression of stable single-chain T cell receptors

Anti-CD22 Immunotoxin RFB4(dsFv)-PE38 (BL22) for CD22-Positive Hematologic Malignancies of Childhood: Preclinical Studies and Phase I Clinical Trial

(2010) A. S. Wayne et al.   CLINICAL CANCER RESEARCH

Stability engineering of scFvs for the development of bispecific and multivalent antibodies

(2010) Brian R. Miller et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Fluorine substitutions in an antigenic peptide selectively modulate T-cell receptor binding in a minimally perturbing manner

(2009) Kurt H. Piepenbrink et al.   BIOCHEMICAL JOURNAL

The promise and potential pitfalls of chimeric antigen receptors

(2009) Michel Sadelain et al.   CURRENT OPINION IN IMMUNOLOGY

Germ Line-governed Recognition of a Cancer Epitope by an Immunodominant Human T-cell Receptor

(2009) David K. Cole et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Recurrence of Intracranial Tumors following Adoptive T Cell Therapy Can Be Prevented by Direct and Indirect Killing Aided by High Levels of Tumor Antigen Cross-Presented on Stromal Cells

(2009) D. L. Thomas et al.   JOURNAL OF IMMUNOLOGY

The influence of the framework core residues on the biophysical properties of immunoglobulin heavy chain variable domains

(2009) Annemarie Honegger et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Different Thermodynamic Binding Mechanisms and Peptide Fine Specificities Associated with a Panel of Structurally Similar High-Affinity T Cell Receptors†‡

(2008) Lindsay L. Jones et al.   BIOCHEMISTRY

Equilibrium between Host and Cancer Caused by Effector T Cells Killing Tumor Stroma

(2008) B. Zhang et al.   CANCER RESEARCH

T-cell receptor binding affinities and kinetics: impact on T-cell activity and specificity

(2008) Jennifer D. Stone et al.   IMMUNOLOGY

The Human Combinatorial Antibody Library HuCAL GOLD Combines Diversification of All Six CDRs According to the Natural Immune System with a Novel Display Method for Efficient Selection of High-Affinity Antibodies

(2008) Christine Rothe et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural features of T cell receptor variable regions that enhance domain stability and enable expression as single-chain VαVβ fragments

(2008) Sarah A. Richman et al.   MOLECULAR IMMUNOLOGY

Control of HIV-1 immune escape by CD8 T cells expressing enhanced T-cell receptor

(2008) Angel Varela-Rohena et al.   NATURE MEDICINE

Tumor Regression in Cancer Patients by Very Low Doses of a T Cell-Engaging Antibody

(2008) R. Bargou et al.   SCIENCE