Identification and optimization of small-molecule agonists of the human relaxin hormone receptor RXFP1

BLOOD HYPEROSMOLARITY AS A PREDICTOR OF MORTALITY IN PATIENTS AFTER ACUTE CORONARY SYNDROME: HOW DEHYDRATION AFFECTS THE PROGNOSIS OF OUR PATIENTS

(2013) Sem Briongos-Figuero et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Relaxin Family Peptides and Their Receptors

(2013) R. A. D. Bathgate et al.   PHYSIOLOGICAL REVIEWS

Serelaxin, recombinant human relaxin-2, for treatment of acute heart failure (RELAX-AHF): a randomised, placebo-controlled trial

(2012) John R Teerlink et al.   LANCET

Relaxin increases human endothelial progenitor cell NO and migration and vasculogenesis in mice

(2011) M. S. Segal et al.   BLOOD

Decreased Expression and Androgen Regulation of the Tumor Suppressor Gene INPP4B in Prostate Cancer

(2011) Myles C. Hodgson et al.   CANCER RESEARCH

Relaxin remodels fibrotic healing following myocardial infarction

(2011) Chrishan S Samuel et al.   LABORATORY INVESTIGATION

Relaxin ameliorates salt-sensitive hypertension and renal fibrosis

(2011) T. Yoshida et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Selective Modulation of Gq/Gs pathways by Naphtho Pyrano Pyrimidines As Antagonists of the Neuropeptide S Receptor

(2010) Joshua G. McCoy et al.   ACS Chemical Neuroscience

Heart Disease and Stroke Statistics—2011 Update

(2010) Véronique L. Roger et al.   CIRCULATION

Activation of Relaxin-Related Receptors by Short, Linear Peptides Derived from a Collagen-Containing Precursor

(2009) Ronen Shemesh et al.   Annals of the New York Academy of Sciences

Scientific Rationale and Design of a Phase I Safety Study of Relaxin in Women with Severe Preeclampsia

(2009) Elaine Unemori et al.   Annals of the New York Academy of Sciences

Relaxin for the treatment of patients with acute heart failure (Pre-RELAX-AHF): a multicentre, randomised, placebo-controlled, parallel-group, dose-finding phase IIb study

(2009) John R Teerlink et al.   LANCET

Cardiovascular effects of relaxin: from basic science to clinical therapy

(2009) Xiao-Jun Du et al.   Nature Reviews Cardiology

Cloning, Expression, and Functional Characterization of Relaxin Receptor (Leucine-Rich Repeat-Containing G Protein-Coupled Receptor 7) Splice Variants from Human Fetal Membranes

(2007) András Kern et al.   ENDOCRINOLOGY