Thymic epithelial cell expansion through matricellular protein CYR61 boosts progenitor homing and T-cell output

Role of β-catenin-regulated CCN matricellular proteins in epithelial repair after inflammatory lung injury

(2013) Rachel L. Zemans et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

CCN1: a novel inflammation-regulated biphasic immune cell migration modulator

(2012) Madlen Löbel et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Cyr61 Induces IL-6 Production by Fibroblast-like Synoviocytes Promoting Th17 Differentiation in Rheumatoid Arthritis

(2012) J. Lin et al.   JOURNAL OF IMMUNOLOGY

Interleukin-22 Drives Endogenous Thymic Regeneration in Mice

(2012) J. A. Dudakov et al.   SCIENCE

Mst1 regulates integrin-dependent thymocyte trafficking and antigen recognition in the thymus

(2012) Yoshihiro Ueda et al.   Nature Communications

The NLRP3 Inflammasome Promotes Age-Related Thymic Demise and Immunosenescence

(2012) Yun-Hee Youm et al.   Cell Reports

Stromal Cell–Immune Cell Interactions

(2011) Ramon Roozendaal et al.   Annual Review of Immunology

Silencing of c-Fos expression by microRNA-155 is critical for dendritic cell maturation and function

(2011) I. Dunand-Sauthier et al.   BLOOD

CYR61 controls p53 and NF-κB expression through PI3K/Akt/mTOR pathways in carboplatin-induced ovarian cancer cells

(2011) Kwang-Beom Lee et al.   CANCER LETTERS

CCN1/CYR61: the very model of a modern matricellular protein

(2011) Lester F. Lau   CELLULAR AND MOLECULAR LIFE SCIENCES

Probing gene function in thymic epithelial cells

(2011) Martin Aichinger et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Structure and function of the thymic microenvironment

(2011) Nancy Ruth Manley   Frontiers in Bioscience-Landmark

The Matricellular Protein Cysteine-rich Protein 61 (CCN1/Cyr61) Enhances Physiological Adaptation of Retinal Vessels and Reduces Pathological Neovascularization Associated with Ischemic Retinopathy

(2011) Adeel Hasan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cyr61/CCN1 signaling is critical for epithelial-mesenchymal transition and stemness and promotes pancreatic carcinogenesis

(2011) Inamul Haque et al.   Molecular Cancer

The thymic epithelial microRNA network elevates the threshold for infection-associated thymic involution via miR-29a mediated suppression of the IFN-α receptor

(2011) Aikaterini S Papadopoulou et al.   NATURE IMMUNOLOGY

First use of thymus transplantation therapy for FOXN1 deficiency (nude/SCID): a report of 2 cases

(2010) M. L. Markert et al.   BLOOD

Matricellular Signaling Molecule CCN1 Attenuates Experimental Autoimmune Myocarditis by Acting as a Novel Immune Cell Migration Modulator

(2010) Madlen Rother et al.   CIRCULATION

Cytokine crosstalk for thymic medulla formation

(2010) Takeshi Nitta et al.   CURRENT OPINION IN IMMUNOLOGY

Emerging strategies to boost thymic function

(2010) Georg A Holländer et al.   CURRENT OPINION IN PHARMACOLOGY

The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing

(2010) Joon-Il Jun et al.   NATURE CELL BIOLOGY

Spatial Mapping of Thymic Stromal Microenvironments Reveals Unique Features Influencing T Lymphoid Differentiation

(2009) Ann V. Griffith et al.   IMMUNITY

Thymic progenitor homing and lymphocyte homeostasis are linked via S1P-controlled expression of thymic P-selectin/CCL25

(2009) Klaus Gossens et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IRES-based Vector Coexpressing FGF2 and Cyr61 Provides Synergistic and Safe Therapeutics of Lower Limb Ischemia

(2009) Audrey Rayssac et al.   MOLECULAR THERAPY

Involvement of Cyr61 in growth, migration and metastasis of prostate cancer cells

(2008) Z-J Sun et al.   BRITISH JOURNAL OF CANCER

Thrombin receptor and RhoA mediate cell proliferation through integrins and cysteine-rich protein 61

(2008) Colin T. Walsh et al.   FASEB JOURNAL

Involvement of Hypoxia-inducing Factor-1α-dependent Plasminogen Activator Inhibitor-1 Up-regulation in Cyr61/CCN1-induced Gastric Cancer Cell Invasion

(2008) Ming-Tsan Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY