Epigenetic regulation of the human telomerase reverse transciptase gene: A potential therapeutic target for the treatment of leukemia (Review)

Novel Agents for the Treatment of Acute Myeloid Leukemia in the Older Patient

(2017) Maria R. Baer et al.   Journal of the National Comprehensive Cancer Network

Combining Histone Deacetylase Inhibitor Vorinostat with Aurora Kinase Inhibitors Enhances Lymphoma Cell Killing with Repression of c-Myc, hTERT, and microRNA Levels

(2011) L. Kretzner et al.   CANCER RESEARCH

Cancer Stem Cells in Hematological Disorders: Current and Possible New Therapeutic Approaches

(2011) C. Annaloro et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

DNA methylation changes associated with cancer risk factors and blood levels of vitamin metabolites in a prospective study

(2011) Paolo Vineis et al.   Epigenetics

Epigenetic regulation of somatic angiotensin-converting enzyme by DNA methylation and histone acetylation

(2011) Guillaume Rivière et al.   Epigenetics

Phase I Study of Oral Azacitidine in Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia, and Acute Myeloid Leukemia

(2011) Guillermo Garcia-Manero et al.   JOURNAL OF CLINICAL ONCOLOGY

Low-Dose Decitabine Versus Best Supportive Care in Elderly Patients With Intermediate- or High-Risk Myelodysplastic Syndrome (MDS) Ineligible for Intensive Chemotherapy: Final Results of the Randomized Phase III Study of the European Organisation for Research and Treatment of Cancer Leukemia Group and the German MDS Study Group

(2011) Michael Lübbert et al.   JOURNAL OF CLINICAL ONCOLOGY

hTERT Promotes Imatinib Resistance in Chronic Myeloid Leukemia Cells: Therapeutic Implications

(2011) L. Deville et al.   MOLECULAR CANCER THERAPEUTICS

Phase 2 study of romiplostim in patients with low- or intermediate-risk myelodysplastic syndrome receiving azacitidine therapy

(2010) H. M. Kantarjian et al.   BLOOD

Cancer progenitors and epigenetic contexts: AnXisting connection

(2010) Ruben Agrelo et al.   Epigenetics

Hemimethylation footprints of DNA demethylation in cancer

(2010) Chunbo Shao et al.   Epigenetics

A BAC transgenic reporter recapitulates in vivo regulation of human telomerase reverse transcriptase in development and tumorigenesis

(2010) Wenwen Jia et al.   FASEB JOURNAL

Telomere protein complexes and interactions with telomerase in telomere maintenance

(2010) Alexander Ruvantha Pinto   Frontiers in Bioscience-Landmark

Epigenetic plasticity of hTERT gene promoter determines retinoid capacity to repress telomerase in maturation-resistant acute promyelocytic leukemia cells

(2010) A Azouz et al.   LEUKEMIA

Histone deacetylase inhibitors for the treatment of myelodysplastic syndrome and acute myeloid leukemia

(2010) A Quintás-Cardama et al.   LEUKEMIA

Distinct and Temporal Roles of Nucleosomal Remodeling and Histone Deacetylation in the Repression of the hTERT Gene

(2010) Shuwen Wang et al.   MOLECULAR BIOLOGY OF THE CELL

Chromatin and epigenetic regulation of the telomerase reverse transcriptase gene

(2010) Jiyue Zhu et al.   Protein & Cell

Positive Regulation of Human Telomerase Reverse Transcriptase Gene Expression and Telomerase Activity by DNA Methylation in Pancreatic Cancer

(2009) Alpana Kumari et al.   ANNALS OF SURGICAL ONCOLOGY

hTERTmethylation and expression in gastric cancer

(2009) Carolina Oliveira Gigek et al.   BIOMARKERS

Epigenetic Modifiers: Basic Understanding and Clinical Development

(2009) R. L. Piekarz et al.   CLINICAL CANCER RESEARCH

Genistein depletes telomerase activity through cross-talk between genetic and epigenetic mechanisms

(2009) Yuanyuan Li et al.   INTERNATIONAL JOURNAL OF CANCER

Histone Deacetylase Inhibitors in Cancer Therapy

(2009) Andrew A. Lane et al.   JOURNAL OF CLINICAL ONCOLOGY

Effect of c-MYC and E2F1 Gene Silencing and of 5-Azacytidine Treatment on Telomerase Activity in Pancreatic Cancer-Derived Cell Lines

(2009) Alpana Kumari et al.   PANCREATOLOGY

How Shelterin Protects Mammalian Telomeres

(2008) Wilhelm Palm et al.   Annual Review of Genetics

Telomerase redefined: Integrated regulation of hTR and hTERT for telomere maintenance and telomerase activity

(2007) C.J. Cairney et al.   BIOCHIMIE