Does DNA methylation provide a link between folate and neural tube closure?

Hypomethylation of GRHL3 gene is associated with the occurrence of neural tube defects

(2018) Tian Tian et al.   Epigenomics

Folate-dependent methylation of septins governs ciliogenesis during neural tube closure

(2017) Manami Toriyama et al.   FASEB JOURNAL

Folic Acid Supplementation for the Prevention of Neural Tube Defects

(2017) et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Folate rescues vitamin B12depletion-induced inhibition of nuclear thymidylate biosynthesis and genome instability

(2017) Ashley M. Palmer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epigenomic Landscapes of hESC-Derived Neural Rosettes: Modeling Neural Tube Formation and Diseases

(2017) Cristina Valensisi et al.   Cell Reports

Partitioning of One-Carbon Units in Folate and Methionine Metabolism Is Essential for Neural Tube Closure

(2017) Kit-Yi Leung et al.   Cell Reports

Determining the association between methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms and genomic DNA methylation level: A meta-analysis

(2016) Li Wang et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Twenty Years After Folic Acid Fortification, FDA Ponders Expansion to Corn Masa Flour

(2016) Julie A. Jacob   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Determining the association between methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms and genomic DNA methylation level: A meta-analysis

(2016) Li Wang et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Methylome analysis for spina bifida shows SOX18 hypomethylation as a risk factor with evidence for a complex (epi)genetic interplay to affect neural tube development

(2016) Anne Rochtus et al.   Clinical Epigenetics

Spina bifida in fetus is associated with an altered pattern of DNA methylation in placenta

(2015) Xiaojuan Zhang et al.   JOURNAL OF HUMAN GENETICS

Genetic, Epigenetic, and Environmental Contributions to Neural Tube Closure

(2014) Jonathan J. Wilde et al.   Annual Review of Genetics

DNA methylation aberrations rather than polymorphisms ofFZD3gene increase the risk of spina bifida in a high-risk region for neural tube defects

(2014) Shaofang Shangguan et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Different Epigenetic Alterations Are Associated with Abnormal IGF2/Igf2 Upregulation in Neural Tube Defects

(2014) Baoling Bai et al.   PLoS One

Mutation in Folate Metabolism Causes Epigenetic Instability and Transgenerational Effects on Development

(2013) Nisha Padmanabhan et al.   CELL

Neural Tube Defects, Folic Acid and Methylation

(2013) Apolline Imbard et al.   International Journal of Environmental Research and Public Health

Cats, Frogs, and Snakes

(2011) Michael Obladen   JOURNAL OF CHILD NEUROLOGY

Global DNA hypomethylation is associated with NTD-affected pregnancy: A case-control study

(2010) Xiaoli Chen et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY