TMBIM6 (transmembrane BAX inhibitor motif containing 6) enhances autophagy and reduces renal dysfunction in a cyclosporine A-induced nephrotoxicity model

Beclin-1-mediated autophagy protects spinal cord neurons against mechanical injury-induced apoptosis

(2014) Zhen-Yu Wang et al.   APOPTOSIS

Autophagy protects renal tubular cells against cyclosporine toxicity

(2014) Nicolas Pallet et al.   Autophagy

Acid sphingomyelinase modulates the autophagic process by controlling lysosomal biogenesis in Alzheimer’s disease

(2014) Jong Kil Lee et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Ginseng treatment attenuates autophagic cell death in chronic cyclosporine nephropathy

(2014) Sun Woo Lim et al.   NEPHROLOGY

BAX inhibitor-1-associated V-ATPase glycosylation enhances collagen degradation in pulmonary fibrosis

(2014) M-R Lee et al.   Cell Death & Disease

Autophagy sequesters damaged lysosomes to control lysosomal biogenesis and kidney injury

(2013) Ikuko Maejima et al.   EMBO JOURNAL

Lysosomal impairment in Parkinson's disease

(2013) Benjamin Dehay et al.   MOVEMENT DISORDERS

Autophagy variation within a cell population determines cell fate through selective degradation of Fap-1

(2013) Jacob M. Gump et al.   NATURE CELL BIOLOGY

Distribution of LGR5+ Cells and Associated Implications during the Early Stage of Gastric Tumorigenesis

(2013) Bo Gun Jang et al.   PLoS One

The lysosome: from waste bag to potential therapeutic target

(2013) Hanna Appelqvist et al.   Journal of Molecular Cell Biology

Endoplasmic reticulum protein BI-1 regulates Ca2+-mediated bioenergetics to promote autophagy

(2012) R. Sano et al.   GENES & DEVELOPMENT

Autophagy in proximal tubules protects against acute kidney injury

(2012) Man Jiang et al.   KIDNEY INTERNATIONAL

Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis

(2012) Congcong He et al.   NATURE

The Transcription Factor TFEB Links mTORC1 Signaling to Transcriptional Control of Lysosome Homeostasis

(2012) A. Roczniak-Ferguson et al.   Science Signaling

Chronic Cyclosporine Nephropathy Is Characterized by Excessive Autophagosome Formation and Decreased Autophagic Clearance

(2012) Sun Woo Lim et al.   TRANSPLANTATION

Dissecting the dynamic turnover of GFP-LC3 in the autolysosome

(2011) Hong-Min Ni et al.   Autophagy

BAX inhibitor-1 regulates autophagy by controlling the IRE1α branch of the unfolded protein response

(2011) Karen Castillo et al.   EMBO JOURNAL

Enhanced Lysosomal Activity Is Involved in Bax Inhibitor-1-induced Regulation of the Endoplasmic Reticulum (ER) Stress Response and Cell Death against ER Stress

(2011) Geum-Hwa Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy Protects the Proximal Tubule from Degeneration and Acute Ischemic Injury

(2011) T. Kimura et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Epithelial-to-Mesenchymal Transition Predicts Cyclosporine Nephrotoxicity in Renal Transplant Recipients

(2011) M. Hazzan et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

TFEB Links Autophagy to Lysosomal Biogenesis

(2011) C. Settembre et al.   SCIENCE

Ca2+ Signaling Tools Acquired from Prostasomes Are Required for Progesterone-Induced Sperm Motility

(2011) K.-H. Park et al.   Science Signaling

Physiological significance of selective degradation of p62 by autophagy

(2010) Masaaki Komatsu et al.   FEBS LETTERS

Ubiquitin accumulation in autophagy-deficient mice is dependent on the Nrf2-mediated stress response pathway: a potential role for protein aggregation in autophagic substrate selection

(2010) Brigit E. Riley et al.   JOURNAL OF CELL BIOLOGY

Autophagy in mammalian development and differentiation

(2010) Noboru Mizushima et al.   NATURE CELL BIOLOGY

An Integrative Overview on the Mechanisms Underlying the Renal Tubular Cytotoxicity of Gentamicin

(2010) Y. Quiros et al.   TOXICOLOGICAL SCIENCES

PUMA- and Bax-induced autophagy contributes to apoptosis

(2009) K S Yee et al.   CELL DEATH AND DIFFERENTIATION

PLIC proteins or ubiquilins regulate autophagy-dependent cell survival during nutrient starvation

(2009) Elsa-Noah N'Diaye et al.   EMBO REPORTS

Bax inhibitor 1 regulates ER-stress-induced ROS accumulation through the regulation of cytochrome P450 2E1

(2009) H.-R. Kim et al.   JOURNAL OF CELL SCIENCE

BAX Inhibitor-1 Is a Negative Regulator of the ER Stress Sensor IRE1α

(2009) Fernanda Lisbona et al.   MOLECULAR CELL

Discovery of Atg5/Atg7-independent alternative macroautophagy

(2009) Yuya Nishida et al.   NATURE

Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function

(2009) Paul Saftig et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A Gene Network Regulating Lysosomal Biogenesis and Function

(2009) Marco Sardiello et al.   SCIENCE

Established and Newly Proposed Mechanisms of Chronic Cyclosporine Nephropathy

(2009) Hye Eun Yoon et al.   KOREAN JOURNAL OF INTERNAL MEDICINE

Autophagy: A lysosomal degradation pathway with a central role in health and disease

(2008) Eeva-Liisa Eskelinen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Lysosomal disorders: From storage to cellular damage

(2008) Andrea Ballabio et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Lysosome Biogenesis Mediated by vps-18 Affects Apoptotic Cell Degradation in Caenorhabditis elegans

(2008) Hui Xiao et al.   MOLECULAR BIOLOGY OF THE CELL

Pharmacodynamic monitoring of calcineurin inhibitor therapy: Is there a clinical benefit?

(2008) C. Sommerer et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Lysosomal membrane permeabilization in cell death

(2008) P Boya et al.   ONCOGENE