CRX directs photoreceptor differentiation by accelerating chromatin remodeling at specific target sites

ATAC-Seq analysis reveals a widespread decrease of chromatin accessibility in age-related macular degeneration

(2018) Jie Wang et al.   Nature Communications

The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis

(2017) Issam Aldiri et al.   NEURON

Identification and prediction of alternative transcription start sites that generate rod photoreceptor-specific transcripts from ubiquitously expressed genes

(2017) Evgenya Y. Popova et al.   PLoS One

Cell Type-Specific Epigenomic Analysis Reveals a Uniquely Closed Chromatin Architecture in Mouse Rod Photoreceptors

(2017) Andrew E. O. Hughes et al.   Scientific Reports

Comprehensive Classification of Retinal Bipolar Neurons by Single-Cell Transcriptomics

(2016) Karthik Shekhar et al.   CELL

Recruitment of Rod Photoreceptors from Short-Wavelength-Sensitive Cones during the Evolution of Nocturnal Vision in Mammals

(2016) Jung-Woong Kim et al.   DEVELOPMENTAL CELL

The functional diversity of retinal ganglion cells in the mouse

(2016) Tom Baden et al.   NATURE

A Simple Grammar Defines Activating and Repressing cis -Regulatory Elements in Photoreceptors

(2016) Michael A. White et al.   Cell Reports

Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets

(2015) Evan Z. Macosko et al.   CELL

MEF2D Drives Photoreceptor Development through a Genome-wide Competition for Tissue-Specific Enhancers

(2015) Milena M. Andzelm et al.   NEURON

DNase I hypersensitivity analysis of the mouse brain and retina identifies region-specific regulatory elements

(2015) Matthew S Wilken et al.   Epigenetics & Chromatin

H3K4me3 Breadth Is Linked to Cell Identity and Transcriptional Consistency

(2014) Bérénice A. Benayoun et al.   CELL

Mechanisms of blindness: Animal models provide insight into distinctCRX-associated retinopathies

(2014) Nicholas M. Tran et al.   DEVELOPMENTAL DYNAMICS

OTX2 loss causes rod differentiation defect in CRX-associated congenital blindness

(2014) Jerome E. Roger et al.   JOURNAL OF CLINICAL INVESTIGATION

A comparative encyclopedia of DNA elements in the mouse genome

(2014) Feng Yue et al.   NATURE

Mechanistically Distinct Mouse Models for CRX-Associated Retinopathy

(2014) Nicholas M. Tran et al.   PLoS Genetics

Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes

(2013) Warren A. Whyte et al.   CELL

Conditional knockdown of DNA methyltransferase 1 reveals a key role of retinal pigment epithelium integrity in photoreceptor outer segment morphogenesis

(2013) I. O. Nasonkin et al.   DEVELOPMENT

Transcription Coactivators p300 and CBP Are Necessary for Photoreceptor-Specific Chromatin Organization and Gene Expression

(2013) Anne K. Hennig et al.   PLoS One

Massively parallel in vivo enhancer assay reveals that highly local features determine the cis-regulatory function of ChIP-seq peaks

(2013) M. A. White et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcriptional code and disease map for adult retinal cell types

(2012) Sandra Siegert et al.   NATURE NEUROSCIENCE

Transcriptional Regulation of Neural Retina Leucine Zipper (Nrl), a Photoreceptor Cell Fate Determinant

(2011) Cynthia L. Montana et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CRX ChIP-seq reveals the cis-regulatory architecture of mouse photoreceptors

(2010) J. C. Corbo et al.   GENOME RESEARCH

Sequence features that drive human promoter function and tissue specificity

(2010) J. M. Landolin et al.   GENOME RESEARCH

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

(2010) Sven Heinz et al.   MOLECULAR CELL

GREAT improves functional interpretation of cis-regulatory regions

(2010) Cory Y McLean et al.   NATURE BIOTECHNOLOGY

Transcriptional regulation of photoreceptor development and homeostasis in the mammalian retina

(2010) Anand Swaroop et al.   NATURE REVIEWS NEUROSCIENCE

Inferring Binding Energies from Selected Binding Sites

(2009) Yue Zhao et al.   PLoS Computational Biology

Statistical Modeling of Transcription Factor Binding Affinities Predicts Regulatory Interactions

(2008) Thomas Manke et al.   PLoS Computational Biology