Hierarchical approaches for systems modeling in cardiac development

Cyclic strain anisotropy regulates valvular interstitial cell phenotype and tissue remodeling in three-dimensional culture

(2012) Russell A. Gould et al.   Acta Biomaterialia

Chronological and Morphological Study of Heart Development in the Rat

(2012) Salazar García Marcela et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Computational simulation of hemodynamic-driven growth and remodeling of embryonic atrioventricular valves

(2012) Philip R. Buskohl et al.   Biomechanics and Modeling in Mechanobiology

Collagen gel analysis of epithelial-mesenchymal transition in the embryo heart: An in vitro model system for the analysis of tissue interaction, signal transduction, and environmental effects

(2012) Alejandro Lencinas et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Early cardiac development: a view from stem cells to embryos

(2012) P. Van Vliet et al.   CARDIOVASCULAR RESEARCH

Not just inductive: a crucial mechanical role for the endoderm during heart tube assembly

(2012) V. D. Varner et al.   DEVELOPMENT

Modelling cardiac calcium sparks in a three-dimensional reconstruction of a calcium release unit

(2012) Johan Hake et al.   JOURNAL OF PHYSIOLOGY-LONDON

ArrayExpress update—trends in database growth and links to data analysis tools

(2012) Gabriella Rustici et al.   NUCLEIC ACIDS RESEARCH

Genetic and environmental risk factors in congenital heart disease functionally converge in protein networks driving heart development

(2012) K. Lage et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exome sequencing: Dual role as a discovery and diagnostic tool

(2011) Chee-Seng Ku et al.   ANNALS OF NEUROLOGY

Cooperative and independent activities of Sgt2 and Get5 in the targeting of tail-anchored proteins

(2011) Christian Kohl et al.   BIOLOGICAL CHEMISTRY

Exome Sequencing Identifies SMAD3 Mutations as a Cause of Familial Thoracic Aortic Aneurysm and Dissection With Intracranial and Other Arterial Aneurysms

(2011) Ellen S. Regalado et al.   CIRCULATION RESEARCH

Efficient Computational Methods for Strongly Coupled Cardiac Electromechanics

(2011) S. Land et al.   IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

Software for systems biology: from tools to integrated platforms

(2011) Samik Ghosh et al.   NATURE REVIEWS GENETICS

Genome-wide genetic marker discovery and genotyping using next-generation sequencing

(2011) John W. Davey et al.   NATURE REVIEWS GENETICS

The Cardiac Transcription Network Modulated by Gata4, Mef2a, Nkx2.5, Srf, Histone Modifications, and MicroRNAs

(2011) Jenny Schlesinger et al.   PLoS Genetics

Two-photon microscopy-guided femtosecond-laser photoablation of avian cardiogenesis: noninvasive creation of localized heart defects

(2010) Huseyin C. Yalcin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Thanks be to Zebrafish

(2010) Ruth Williams   CIRCULATION RESEARCH

Genome-wide analysis of promoter architecture in Drosophila melanogaster

(2010) R. A. Hoskins et al.   GENOME RESEARCH

Comprehensive analysis of DNA-methylation in mammalian tissues using MeDIP-chip

(2010) Nina Pälmke et al.   METHODS

Dissecting spatio-temporal protein networks driving human heart development and related disorders

(2010) Kasper Lage et al.   Molecular Systems Biology

The BioPAX community standard for pathway data sharing

(2010) Emek Demir et al.   NATURE BIOTECHNOLOGY

ChIP-Seq identification of weakly conserved heart enhancers

(2010) Matthew J Blow et al.   NATURE GENETICS

Next-generation genomics: an integrative approach

(2010) R. David Hawkins et al.   NATURE REVIEWS GENETICS

Models of cardiac tissue electrophysiology: Progress, challenges and open questions

(2010) R.H. Clayton et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Heart of Newt: A Recipe for Regeneration

(2010) Bhairab N. Singh et al.   Journal of Cardiovascular Translational Research

Collaboratively charting the gene-to-phenotype network of human congenital heart defects

(2010) Roland Barriot et al.   Genome Medicine

Development of an anatomically detailed MRI-derived rabbit ventricular model and assessment of its impact on simulations of electrophysiological function

(2009) Martin J. Bishop et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Microengineered Platforms for Cell Mechanobiology

(2009) Deok-Ho Kim et al.   Annual Review of Biomedical Engineering

NAViGaTOR: Network Analysis, Visualization and Graphing Toronto

(2009) Kevin R. Brown et al.   BIOINFORMATICS

Chromatin remodeling in silico: A stochastic model for SWI/SNF

(2009) Amin R. Mazloom et al.   BIOSYSTEMS

Active Adaptation of the Tethered Mitral Valve

(2009) Jacob P. Dal-Bianco et al.   CIRCULATION

Small Animal Models of Heart Failure

(2009) Richard D. Patten et al.   Circulation-Heart Failure

ChIP–seq: advantages and challenges of a maturing technology

(2009) Peter J. Park   NATURE REVIEWS GENETICS

FieldML: concepts and implementation

(2009) G. R. Christie et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES

Proteomic-Based Detection of a Protein Cluster Dysregulated during Cardiovascular Development Identifies Biomarkers of Congenital Heart Defects

(2009) Anjali K. Nath et al.   PLoS One

Coupling multi-physics models to cardiac mechanics

(2009) D.A. Nordsletten et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Minimum Information About a Microarray Experiment (MIAME) – Successes, Failures, Challenges

(2009) Alvis Brazma   TheScientificWorldJOURNAL

Walking the Interactome for Prioritization of Candidate Disease Genes

(2008) Sebastian Köhler et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Comparing simulation results of SBML capable simulators

(2008) F. T. Bergmann et al.   BIOINFORMATICS

Effects of strain rate, mixing ratio, and stress–strain definition on the mechanical behavior of the polydimethylsiloxane (PDMS) material as related to its biological applications

(2008) Khalil Khanafer et al.   BIOMEDICAL MICRODEVICES

Bioinformatics, multiscale modeling and the IUPS Physiome Project

(2008) P. J. Hunter et al.   BRIEFINGS IN BIOINFORMATICS

Can recent insights into cardiac development improve our understanding of congenitally malformed hearts?

(2008) Thomas Horsthuis et al.   CLINICAL ANATOMY

High-speed imaging of developing heart valves reveals interplay of morphogenesis and function

(2008) P. J. Scherz et al.   DEVELOPMENT

The Cardiac Physiome: perspectives for the future

(2008) James Bassingthwaighte et al.   EXPERIMENTAL PHYSIOLOGY

Prediction of cardiac transcription networks based on molecular data and complex clinical phenotypes

(2008) Martje Toenjes et al.   Molecular BioSystems

Spatially and temporally controlled electroporation of early chick embryos

(2008) Octavian Voiculescu et al.   Nature Protocols

Shared gene expression profiles in developing heart valves and osteoblast progenitor cells

(2008) Santanu Chakraborty et al.   PHYSIOLOGICAL GENOMICS

CellDesigner 3.5: A Versatile Modeling Tool for Biochemical Networks

(2008) A. Funahashi et al.   PROCEEDINGS OF THE IEEE

Protein interactions in human genetic diseases

(2008) Benjamin Schuster-Böckler et al.   GENOME BIOLOGY

Genomic chart guiding embryonic stem cell cardiopoiesis

(2008) Randolph S Faustino et al.   GENOME BIOLOGY

Cancer Epigenetics: Modifications, Screening, and Therapy

(2007) Gal-Yam Einav Nili et al.   Annual Review of Medicine