Large-scale mouse knockouts and phenotypes

Towards an encyclopaedia of mammalian gene function: the International Mouse Phenotyping Consortium

(2012) S. D. M. Brown et al.   Disease Models & Mechanisms

Neighboring-gene effect: a genetic uncertainty principle

(2012) Anastasia Baryshnikova et al.   NATURE METHODS

Systematic identification of gene annotation errors in the widely used yeast mutation collections

(2012) Taly Ben-Shitrit et al.   NATURE METHODS

A knockout mouse resource for the biomedical research community

(2011) K. C. Kent Lloyd   Annals of the New York Academy of Sciences

Reduced Glutathione Enhances Fertility of Frozen/Thawed C57BL/6 Mouse Sperm after Exposure to Methyl-Beta-Cyclodextrin1

(2011) Toru Takeo et al.   BIOLOGY OF REPRODUCTION

The critical role of histone H2A-deubiquitinase Mysm1 in hematopoiesis and lymphocyte differentiation

(2011) A. Nijnik et al.   BLOOD

New approaches to the representation and analysis of phenotype knowledge in human diseases and their animal models

(2011) P. N. Schofield et al.   Briefings in Functional Genomics

Exploring the elephant: histopathology in high-throughput phenotyping of mutant mice

(2011) P. N. Schofield et al.   Disease Models & Mechanisms

Ultrasound Biomicroscopy in Small Animal Research: Applications in Molecular and Preclinical Imaging

(2011) A. Greco et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

A conditional knockout resource for the genome-wide study of mouse gene function

(2011) William C. Skarnes et al.   NATURE

A resource of vectors and ES cells for targeted deletion of microRNAs in mice

(2011) Haydn M Prosser et al.   NATURE BIOTECHNOLOGY

Disruption of mouse Slx4, a regulator of structure-specific nucleases, phenocopies Fanconi anemia

(2011) Gerry P Crossan et al.   NATURE GENETICS

Is the obesity epidemic a national security issue around the globe?

(2011) Barry M. Popkin   Current Opinion in Endocrinology Diabetes and Obesity

The RNA–Methyltransferase Misu (NSun2) Poises Epidermal Stem Cells to Differentiate

(2011) Sandra Blanco et al.   PLoS Genetics

The mouse genetics toolkit: revealing function and mechanism

(2011) Louise van der Weyden et al.   GENOME BIOLOGY

Rapid 3D Phenotyping of Cardiovascular Development in Mouse Embryos by Micro-CT With Iodine Staining

(2010) Karl Degenhardt et al.   Circulation-Cardiovascular Imaging

The Human Phenotype Ontology

(2010) PN Robinson et al.   CLINICAL GENETICS

Phenotype ontologies for mouse and man: bridging the semantic gap

(2010) P. N. Schofield et al.   Disease Models & Mechanisms

Standard operating procedures for describing and performing metabolic tests of glucose homeostasis in mice

(2010) J. E. Ayala et al.   Disease Models & Mechanisms

Phenotypic annotation of the mouse X chromosome

(2010) B. J. Cox et al.   GENOME RESEARCH

Optimized Cryopreservation of Mouse Sperm Based on Fertilization Rate

(2010) Mary L. BATH   JOURNAL OF REPRODUCTION AND DEVELOPMENT

Combination medium of cryoprotective agents containing l-glutamine and methyl-β-cyclodextrin in a preincubation medium yields a high fertilization rate for cryopreserved C57BL/6J mouse sperm

(2010) T Takeo et al.   LABORATORY ANIMALS

Optimising experimental design for high-throughput phenotyping in mice: a case study

(2010) Natasha A. Karp et al.   MAMMALIAN GENOME

Mouse phenotyping

(2010) Helmut Fuchs et al.   METHODS

High-throughput mouse phenotyping

(2010) Hilary Gates et al.   METHODS

A mouse knockout library for secreted and transmembrane proteins

(2010) Tracy Tang et al.   NATURE BIOTECHNOLOGY

Inhibition of In Vitro Fertilizing Capacity of Cryopreserved Mouse Sperm by Factors Released by Damaged Sperm, and Stimulation by Glutathione

(2010) Mary L. Bath   PLoS One

Genetic influence on electrocardiogram time intervals and heart rate in aging mice

(2009) Shuqin Xing et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The German Mouse Clinic: A Platform for Systemic Phenotype Analysis of Mouse Models

(2009) H. Fuchs et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Introduction to the Japan Mouse Clinic at the RIKEN BioResource Center

(2009) Shigeharu WAKANA et al.   EXPERIMENTAL ANIMALS

Agouti C57BL/6N embryonic stem cells for mouse genetic resources

(2009) Stephen J Pettitt et al.   NATURE METHODS

EuroPhenome: a repository for high-throughput mouse phenotyping data

(2009) Hugh Morgan et al.   NUCLEIC ACIDS RESEARCH

EMMA--mouse mutant resources for the international scientific community

(2009) P. Wilkinson et al.   NUCLEIC ACIDS RESEARCH

Phenotypic characterization of epiphycan-deficient and epiphycan/biglycan double-deficient mice

(2009) S. Nuka et al.   OSTEOARTHRITIS AND CARTILAGE

The mammalian phenotype ontology: enabling robust annotation and comparative analysis

(2009) Cynthia L. Smith et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

Attribution of vascular phenotypes of the murine Egfl7 locus to the microRNA miR-126

(2008) F. Kuhnert et al.   DEVELOPMENT

Removing the cloak of invisibility: phenotyping the mouse

(2008) M. J. Justice   Disease Models & Mechanisms

Large-scale gene trapping in C57BL/6N mouse embryonic stem cells

(2008) G. M. Hansen et al.   GENOME RESEARCH

Behavioral Differences among C57BL/6 Substrains: Implications for Transgenic and Knockout Studies

(2008) Camron D. Bryant et al.   JOURNAL OF NEUROGENETICS

Will All Americans Become Overweight or Obese? Estimating the Progression and Cost of the US Obesity Epidemic

(2008) Youfa Wang et al.   Obesity

High-throughput Screening of Mouse Knockout Lines Identifies True Lean and Obese Phenotypes

(2008) Robert Brommage et al.   Obesity

Reliability, robustness, and reproducibility in mouse behavioral phenotyping: a cross-laboratory study

(2008) Silvia Mandillo et al.   PHYSIOLOGICAL GENOMICS

Conserving, Distributing and Managing Genetically Modified Mouse Lines by Sperm Cryopreservation

(2008) G. Charles Ostermeier et al.   PLoS One

Whole Mount Enzyme Histochemistry as a Rapid Screen at Necropsy for Expression of β-Galactosidase (LacZ)–Bearing Transgenes: Considerations for Separating Specific LacZ Activity from Nonspecific (Endogenous) Galactosidase Activity

(2008) Brad Bolon   TOXICOLOGIC PATHOLOGY

Methyl-Beta-Cyclodextrin Improves Fertilizing Ability of C57BL/6 Mouse Sperm after Freezing and Thawing by Facilitating Cholesterol Efflux from the Cells1

(2007) Toru Takeo et al.   BIOLOGY OF REPRODUCTION