The mouse genetics toolkit: revealing function and mechanism

A Rapid and Scalable System for Studying Gene Function in Mice Using Conditional RNA Interference

(2011) Prem K. Premsrirut et al.   CELL

Rapid derivation of genetically related mutants from embryonic cells harboring a recombinase-specificTrp53platform

(2011) Quan-Xiang Wei et al.   CELL CYCLE

Recombinase-Mediated Cassette Exchange (RMCE): Traditional Concepts and Current Challenges

(2011) Soeren Turan et al.   JOURNAL OF MOLECULAR BIOLOGY

SLX4, a coordinator of structure-specific endonucleases, is mutated in a new Fanconi anemia subtype

(2011) Chantal Stoepker et al.   NATURE GENETICS

Disruption of mouse Slx4, a regulator of structure-specific nucleases, phenocopies Fanconi anemia

(2011) Gerry P Crossan et al.   NATURE GENETICS

Mutations of the SLX4 gene in Fanconi anemia

(2011) Yonghwan Kim et al.   NATURE GENETICS

AGRP neurons are sufficient to orchestrate feeding behavior rapidly and without training

(2011) Yexica Aponte et al.   NATURE NEUROSCIENCE

Reversible suppression of an essential gene in adult mice using transgenic RNA interference

(2011) K. McJunkin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A new technique for controlling the brain: optogenetics and its potential for use in research and the clinic

(2010) Ryan T. LaLumiere   Brain Stimulation

Progress and prospects: oligonucleotide-directed gene modification in mouse embryonic stem cells: a route to therapeutic application

(2010) M Aarts et al.   GENE THERAPY

When Cre-Mediated Recombination in Mice Does Not Result in Protein Loss

(2010) K. A. Turlo et al.   GENETICS

Mouse phenotyping

(2010) Helmut Fuchs et al.   METHODS

Genetic screens using the piggyBac transposon

(2010) Su Kit Chew et al.   METHODS

Genetic dissection of an amygdala microcircuit that gates conditioned fear

(2010) Wulf Haubensak et al.   NATURE

Dual RMCE for efficient re-engineering of mouse mutant alleles

(2010) Marco Osterwalder et al.   NATURE METHODS

Recombinase mediated cassette exchange into genomic targets using an adenovirus vector

(2010) David A. Sorrell et al.   NUCLEIC ACIDS RESEARCH

The Mouse Genome Database (MGD): premier model organism resource for mammalian genomics and genetics

(2010) J. A. Blake et al.   NUCLEIC ACIDS RESEARCH

Ensembl 2011

(2010) P. Flicek et al.   NUCLEIC ACIDS RESEARCH

The IKMC web portal: a central point of entry to data and resources from the International Knockout Mouse Consortium

(2010) M. Ringwald et al.   NUCLEIC ACIDS RESEARCH

Efficient Generation of Germ Line Transmitting Chimeras from C57BL/6N ES Cells by Aggregation with Outbred Host Embryos

(2010) Marina Gertsenstein et al.   PLoS One

Gene targeting by homologous recombination in mouse zygotes mediated by zinc-finger nucleases

(2010) M. Meyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PiggyBac Transposon Mutagenesis: A Tool for Cancer Gene Discovery in Mice

(2010) R. Rad et al.   SCIENCE

Where to go with FTO?

(2010) Rachel Larder et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Transposon-mediated BAC transgenesis in zebrafish and mice

(2009) Maximiliano L Suster et al.   BMC GENOMICS

A Modified Sleeping Beauty Transposon System That Can Be Used to Model a Wide Variety of Human Cancers in Mice

(2009) A. J. Dupuy et al.   CANCER RESEARCH

International Gene Trap Project: Towards Gene-driven Saturation Mutagenesis in Mice

(2009) Masatake Araki et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Dre recombinase, like Cre, is a highly efficient site-specific recombinase in E. coli, mammalian cells and mice

(2009) K. Anastassiadis et al.   Disease Models & Mechanisms

Virus-free induction of pluripotency and subsequent excision of reprogramming factors

(2009) Keisuke Kaji et al.   NATURE

A conditional transposon-based insertional mutagenesis screen for genes associated with mouse hepatocellular carcinoma

(2009) Vincent W Keng et al.   NATURE BIOTECHNOLOGY

Agouti C57BL/6N embryonic stem cells for mouse genetic resources

(2009) Stephen J Pettitt et al.   NATURE METHODS

Generation of transgene-free induced pluripotent mouse stem cells by the piggyBac transposon

(2009) Kosuke Yusa et al.   NATURE METHODS

A high-throughput splinkerette-PCR method for the isolation and sequencing of retroviral insertion sites

(2009) Anthony G Uren et al.   Nature Protocols

EMMA--mouse mutant resources for the international scientific community

(2009) P. Wilkinson et al.   NUCLEIC ACIDS RESEARCH

MouseBook: an integrated portal of mouse resources

(2009) Andrew Blake et al.   NUCLEIC ACIDS RESEARCH

Long human CHGA flanking chromosome 14 sequence required for optimal BAC transgenic “rescue” of disease phenotypes in the mouse Chga knockout

(2009) Sucheta M. Vaingankar et al.   PHYSIOLOGICAL GENOMICS

A Transposon-Based Genetic Screen in Mice Identifies Genes Altered in Colorectal Cancer

(2009) T. K. Starr et al.   SCIENCE

Lineage-Specific Biology Revealed by a Finished Genome Assembly of the Mouse

(2009) Deanna M. Church et al.   PLOS BIOLOGY

Deep short-read sequencing of chromosome 17 from the mouse strains A/J and CAST/Ei identifies significant germline variation and candidate genes that regulate liver triglyceride levels

(2009) Ian Sudbery et al.   GENOME BIOLOGY

Mapping multiprotein complexes by affinity purification and mass spectrometry

(2008) Mark O Collins et al.   CURRENT OPINION IN BIOTECHNOLOGY

The Collaborative Cross at Oak Ridge National Laboratory: developing a powerful resource for systems genetics

(2008) Elissa J. Chesler et al.   MAMMALIAN GENOME

Contemporary approaches for modifying the mouse genome

(2008) David J. Adams et al.   PHYSIOLOGICAL GENOMICS

Reliability, robustness, and reproducibility in mouse behavioral phenotyping: a cross-laboratory study

(2008) Silvia Mandillo et al.   PHYSIOLOGICAL GENOMICS

Species Specificity in Major Urinary Proteins by Parallel Evolution

(2008) Darren W. Logan et al.   PLoS One

Efficient In Vivo Targeting of Epidermal Stem Cells by Early Gestational Intraamniotic Injection of Lentiviral Vector Driven by the Keratin 5 Promoter

(2007) Masayuki Endo et al.   MOLECULAR THERAPY