Review
Agriculture, Dairy & Animal Science
Dong Qiao Peng, Stephen B. Smith, Hong Gu Lee
Summary: The development of intramuscular adipose tissue and muscle in cattle is dependent on cell hyperplasia and hypertrophy, with Vitamin A playing a regulatory role in both processes. Vitamin A supplementation and restriction have opposite effects on adipose tissue development and muscle growth in beef cattle. The timing and level of Vitamin A restriction can interact with the alcohol dehydrogenase-1C (ADH1C) genotype to impact marbling and intramuscular adipose tissue development in cattle, ultimately affecting beef quality.
JOURNAL OF ANIMAL SCIENCE AND BIOTECHNOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Songling Jiang, Lingjuan Piao, Eun Bi Ma, Hunjoo Ha, Joo Young Huh
Summary: This study investigated the regulation of FNDC5 expression and irisin in circulation in type 1 and type 2 diabetic mice, and their relationship with metabolic parameters. The results showed that circulating irisin and subcutaneous fat FNDC5 gene expression were downregulated in diabetic and obese mice. Plasma irisin levels correlated positively with subcutaneous fat FNDC5 expression and negatively with markers of insulin resistance.
Review
Endocrinology & Metabolism
Fang Zhang, Xiaohui Pan, Xinyue Zhang, Nanwei Tong
Summary: TZDs have a positive impact on fat remodeling and improve insulin sensitivity, suggesting a potentially valuable approach in cardiometabolic risk management.
Review
Endocrinology & Metabolism
Ruping Pan, Yong Chen
Summary: Obesity is characterized by the overaccumulation of white adipose tissue in the body, leading to various metabolic disorders. Targeting human thermogenic adipose tissues shows promise in combating obesity.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Binglin Yue, Hui Wang, Xin Cai, Jiabo Wang, Zhixin Chai, Wei Peng, Shi Shu, Changqi Fu, Jincheng Zhong
Summary: Adipose tissue-secreted exosomes play a significant role in the intercellular communication between organs, especially with skeletal muscle. These exosomes transfer various molecules that can affect the physiological and pathological processes in recipient cells. Therefore, studying the regulatory mechanisms of adipose-secreted exosomes and their cellular crosstalk with skeletal muscle is of great importance.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biology
Xiao Zhang, Hero Robles, Kristann L. Magee, Madelyn R. Lorenz, Zhaohua Wang, Charles A. Harris, Clarissa S. Craft, Erica L. Scheller
Summary: Bone marrow adipocytes accumulate with age and in diverse disease states. A novel secondary adipogenesis pathway unique to the bone marrow is activated with age and in states of metabolic stress, resulting in compromised lipid mobilization and cytokine expression within regions traditionally devoted to hematopoiesis. This finding further contributes to our understanding of bone marrow adipocyte origins, adaptations, and relationships with surrounding tissues.
Article
Microbiology
Henrique Machado, Peter Hofer, Rudolf Zechner, Terry K. Smith, Luisa M. Figueiredo
Summary: In African trypanosomiasis, lipolysis of adipose tissue is activated early in infection, which limits parasite growth and affects the loss of fat mass.
NATURE MICROBIOLOGY
(2023)
Article
Endocrinology & Metabolism
Pavel Hruska, Jan Kucera, Matej Pekar, Pavol Holeczy, Miloslav Mazur, Marek Buzga, Daniela Kuruczova, Peter Lenart, Jana Fialova Kucerova, David Potesil, Zbynek Zdrahal, Julie Bienertova-Vasku
Summary: The study compared the proteomic profiles of mature adipocytes from different adipose tissue depots, with findings showing that subcutaneous adipocytes are more active in vesicular transport, secretion, and lipid metabolism, while visceral adipocytes have higher protein expression related to mitochondrial energy metabolism and translational or biosynthetic activity.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Biochemistry & Molecular Biology
Junli Feng, Xi Chen, Shitong Wang, Jian Zhang, Qingcheng Wang, Shunyuan Guo, Qing Shen
Summary: In this study, the metabolic effects of seafood-derived plasmalogens (Pls) on high fat diet-induced hyperlipidemia in zebrafish were evaluated. It was found that Pls supplementation effectively alleviated obesity symptoms and reduced levels of total hepatic cholesterol and triglycerides. The study also revealed that Pls mainly altered lipid metabolism pathways and the TCA cycle, induced the overexpression of anti-oxidation enzymes, and reduced disease biomarkers and gut microbiota-derived metabolites.
Article
Multidisciplinary Sciences
Astrid L. Basse, Karen N. Nielsen, Iuliia Karavaeva, Lars R. Ingerslev, Tao Ma, Jesper F. Havelund, Thomas S. Nielsen, Mikkel Frost, Julia Peics, Emilie Dalbram, Morten Dall, Juleen R. Zierath, Romain Barres, Nils J. Faergeman, Jonas T. Treebak, Zachary Gerhart-Hines
Summary: NAMPT controls the molecular clock and metabolic biorhythms in a tissue-specific manner. It plays a key role in the amplitude of the core clock in brown adipose tissue, has moderate dependence on NAD+ biosynthesis in white adipose tissue, and is completely refractory to loss in skeletal muscle. NAMPT also differentially orchestrates oscillation of clock-controlled gene networks and metabolite levels in different tissues.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2023)
Article
Biochemistry & Molecular Biology
Gege Liu, Lixia Chen, Haining Tian, Guoliang Sun, Fulei Wei, Yuqiong Meng, Rui Ma
Summary: The study found that triploid rainbow trout can adapt to different levels of dietary lipids by coordinating metabolism in different tissues. The liver plays a key role in lipid metabolism, with low lipid diets leading to increased lipid transport and glycolysis. Moderate lipid intake enhances lipid uptake and lipogenesis in muscle, while excess lipids are preferentially stored in abdominal adipose tissue through coordinated fatty acid uptake and de novo synthesis.
Article
Geriatrics & Gerontology
Karin J. C. Sanders, Roel Wierts, Wouter D. Marken Lichtenbelt, Judith Vos-Geelen, Guy Plasqui, Marco C. J. M. Kelders, Vera B. Schrauwen-Hinderling, Jan Bucerius, Anne-Marie C. Dingemans, Felix M. Mottaghy, Annemie M. W. J. Schols
Summary: There is no correlation between basal metabolic rate (BMR), total daily energy expenditure (TDEE), and brown adipose tissue (BAT) activity in patients with chronic obstructive pulmonary disease (COPD). Additionally, BAT activity and gene expression levels of brown adipocyte or beige markers are comparable between COPD patients and controls.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
(2022)
Article
Neurosciences
William V. Trim, Jean-Philippe Walhin, Francoise Koumanov, Anne Bouloumie, Mark A. Lindsay, Yung-Chih Chen, Rebecca L. Travers, James E. Turner, Dylan Thompson
Summary: The study reveals that adipose tissue shows significant pro-inflammatory changes with age in healthy and lean older adults, while skeletal muscle does not. These changes are tissue-specific and more profound than those observed in circulation or skeletal muscle. Adipose tissue's role in the biological ageing process in humans is highlighted, showing signs of immunometabolic dysfunction before systemic manifestation.
JOURNAL OF PHYSIOLOGY-LONDON
(2022)
Article
Multidisciplinary Sciences
Takayuki Yamamoto, Kazushi Sugimoto, Syuhei Ichikawa, Kei Suzuki, Hideki Wakabayashi, Kaoru Dohi, Norihiko Yamamoto
Summary: This study investigated the relationship between body composition and the prognosis of COVID-19. The results showed that high intra-muscular adipose tissue content (IMAC) may predict the severe disease course of COVID-19 in non-obese Japanese patients, but it did not predict disease severity in obese patients or mortality.
Article
Agriculture, Dairy & Animal Science
Siyuan Wang, Jie Liu, Weiming Zhao, Guofu Wang, Shuxin Gao
Summary: This study examined the differences between BF and PF in Angus and Simmental cattle, revealing that BF has smaller cell area but greater lipid deposition ability. RNA-seq identified a large number of genes, indicating that genes related to fat metabolism were highly expressed in four tissues, and DEGs differed significantly between Angus and Simmental cattle.
ANIMAL BIOTECHNOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Deyamira Matuz-Mares, Alain Hernandez-Vazquez, Hector Riveros-Rosas, Raquel Guinzberg, Tania Quesada-Lopez, Alfonso Carabez-Trejo, Ofelia Mora, Enrique Pina
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
(2018)
Article
Food Science & Technology
Sarahi Rodriguez-Gonzalez, Iza F. Perez-Ramirez, Diana M. Amaya-Cruz, Marco A. Gallegos-Corona, Minerva Ramos-Gomez, Ofelia Mora, Rosalia Reynoso-Camacho
JOURNAL OF FUNCTIONAL FOODS
(2018)
Article
Agriculture, Dairy & Animal Science
Ofelia Mora Izaguirre, Katrin Quester, Vitalii Petranovski, Laura Gonzalez Davalos, Enrique Pina Garza, Armando Shimada Miyasaka, Rafael Vazquez-Duhalt
REVISTA MEXICANA DE CIENCIAS PECUARIAS
(2018)
Article
Food Science & Technology
Iza F. Perez-Ramirez, Marco A. Gallegos-Corona, Maria L. Gonzalez-Davalos, Ofelia Mora, Nuria E. Rocha-Guzman, Rosalia Reynoso-Camacho
EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY
(2019)
Article
Cell & Tissue Engineering
Magdalena Arevalo-Turrubiarte, Chiara Olmeo, Paolo Accornero, Mario Baratta, Eugenio Martignani
STEM CELL RESEARCH
(2019)
Article
Food Science & Technology
Iza F. Perez-Ramirez, Maria L. Gonzalez-Davalos, Ofelia Mora, Isaac Silva, Marco A. Gallegos-Corona, Salvador H. Guzman-Maldonado, Rosalia Reynoso-Camacho
EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY
(2019)
Article
Dentistry, Oral Surgery & Medicine
Rosa M. Perez-Serrano, Ana I. Soza-Bolanos, Samantha N. Castillo-Valdes, Gabriela Hernandez-Valdez, Ofelia Mora-Izaguirre, Maria L. Gonzalez-Davalos, Till Dammaschke, Ruben A. Dominguez-Perez
Summary: Research showed that four contemporary endodontic set sealers promoted similar production of four cytokines in a short time, while their concentrations decreased rapidly to nearly undetectable levels within 24 hours. This suggests that these endodontic set sealers do not possess inflammatory properties, making them suitable for long-term clinical use.
AUSTRALIAN ENDODONTIC JOURNAL
(2021)
Article
Biochemistry & Molecular Biology
Aparicio-Fernandez Xochitl, Reynoso-Camacho Rosalia, Ramos-Gomez Minerva, Magdalena Mendoza-Sanchez, Ofelia Mora, Iza F. Perez-Ramirez
Summary: The oat sprouts extract showed a greater effect than oat grains on the regulation of genes linked to glucose and lipid metabolisms in adipocytes, mainly due to its high content of avenanthramides and other bioactive compounds. This study highlights the potential health benefits of oat sprouts and provides insights for identifying oat varieties with high nutraceutical potential based on their bioactive compound content.
JOURNAL OF FOOD BIOCHEMISTRY
(2021)
Article
Agriculture, Dairy & Animal Science
Mariana Aguilar-Gonzalez, German Buitron, Armando Shimada, Jorge Ayala-Sumuano, Laura Gonzalez-Davalos, Alfredo Varela-Echavarria, Ofelia Mora
Summary: The work aimed to modify the metabolic activity of rumen microorganisms by applying an electric potential, which resulted in enhanced production of acetate, propionate, and butyrate.
JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION
(2023)
Article
Agriculture, Dairy & Animal Science
Sarahi Rodriguez-Gonzalez, Laura Gonzalez-Davalos, Carolina Robles-Rodriguez, Carlos Lozano-Flores, Alfredo Varela-Echavarria, Armando Shimada, Ofelia Mora-Izaguirre
Summary: This study investigates bacterial consortia isolated from the rumen of calves and identifies A1D42 and A3D42 as potential probiotics for calves, based on their characteristics and adaptation to different growth conditions.
JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION
(2023)
Article
Biochemistry & Molecular Biology
Haiku D. J. Gomez-Velazquez, Xochitl Aparicio-Fernandez, Ofelia Mora, Maria Laura Gonzalez Davalos, Erika A. de los Rios, Rosalia Reynoso-Camacho
Summary: Germination and chemical elicitation can increase the nutrient and phytochemical content of chia sprouts, benefiting obesity and its complications.
JOURNAL OF FOOD BIOCHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Alexandro Escobar-Ortiz, Diego Hernandez-Saavedra, Jaime Lizardi-Mendoza, Iza Fernanda Perez-Ramirez, Ofelia Mora-Izaguirre, Minerva Ramos-Gomez, Rosalia Reynoso-Camacho
Summary: This study evaluated the protective effect of a diet supplemented with cricket flour on obesity control and its complications. The results showed that cricket supplementation reduced body weight gain and serum triglycerides, improved insulin resistance, and inhibited pancreatic lipase. Cricket consumption is a valuable strategy to reduce the comorbidities associated with diet-induced obesity.
JOURNAL OF FOOD BIOCHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Francisco Campos-Maldonado, Maria L. Gonzalez-Davalos, Enrique Pina, Miriam Aracely Anaya-Loyola, Armando Shimada, Alfredo Varela-Echavarria, Ofelia Mora
Summary: The study found that high levels of fructose promoted differentiation of pig newborn mesenchymal stem cells into adipocytes, leading to significantly increased oxidative reactions and ROS production. These results suggest that fructose plays an important role in adipogenesis in animals.
JOURNAL OF FOOD BIOCHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Josue Manriquez-Nunez, Ofelia Mora, Francesc Villarroya, Rosalia Reynoso-Camacho, Iza Fernanda Perez-Ramirez, Minerva Ramos-Gomez
Summary: Current research focuses on bioactive compounds that have the potential to promote macrophage polarization in order to reduce the development of inflammatory-related diseases. However, the effect of bioactive compounds under oxidative-stress-induced hyperglycemia on macrophage polarization has been insufficiently investigated. Our results indicate that hyperglycemia plays a fundamental role in modulating macrophage-induced inflammation in response to bioactive compounds.
Article
Agriculture, Dairy & Animal Science
Carolina Robles-Rodriguez, Vijaykumar Yogesh Muley, Maria Laura Gonzalez-Davalos, Armando Shimada, Alfredo Varela-Echavarria, Ofelia Mora
Summary: The rumen and the jejunum of calves have different functional roles and their microbiomes undergo dynamic changes after birth. We sequenced and characterized the microbiomes of these organs in Bos indicus calves and observed a shift in dominant microbial species over time. Prevotella species predominate in the rumen, while the jejunum microbiome consists of small proportions of several genera. Overall, the rumen and the jejunum microbiomes are replaced by new microbiomes shortly after birth.
ANIMAL SCIENCE JOURNAL
(2023)