Modulation of deregulated chaperone-mediated autophagy by a phosphopeptide

Pharmacological regulators of autophagy and their link with modulators of lupus disease

(2014) Frédéric Gros et al.   BRITISH JOURNAL OF PHARMACOLOGY

HSPA8/HSC70 chaperone protein

(2013) François Stricher et al.   Autophagy

Lupuzor/P140 peptide in patients with systemic lupus erythematosus: a randomised, double-blind, placebo-controlled phase IIb clinical trial

(2012) Robert Zimmer et al.   ANNALS OF THE RHEUMATIC DISEASES

Macroautophagy is deregulated in murine and human lupus T lymphocytes

(2012) Frédéric Gros et al.   Autophagy

Peptide-based approaches to treat lupus and other autoimmune diseases

(2012) Nicolas Schall et al.   JOURNAL OF AUTOIMMUNITY

Salmonella infects B cells by macropinocytosis and formation of spacious phagosomes but does not induce pyroptosis in favor of its survival

(2012) Roberto Rosales-Reyes et al.   MICROBIAL PATHOGENESIS

Autophagy modulation as a potential therapeutic target for diverse diseases

(2012) David C. Rubinsztein et al.   NATURE REVIEWS DRUG DISCOVERY

New insights into mechanisms of therapeutic effects of antimalarial agents in SLE

(2012) Daniel J. Wallace et al.   Nature Reviews Rheumatology

Chaperone-mediated autophagy: a unique way to enter the lysosome world

(2012) Susmita Kaushik et al.   TRENDS IN CELL BIOLOGY

Autophagy in the regulation of pathogen replication and adaptive immunity

(2012) Felix Randow et al.   TRENDS IN IMMUNOLOGY

Microautophagy of Cytosolic Proteins by Late Endosomes

(2011) Ranjit Sahu et al.   DEVELOPMENTAL CELL

Autophagy in immunity and inflammation

(2011) Beth Levine et al.   NATURE

A photoconvertible fluorescent reporter to track chaperone-mediated autophagy

(2011) Hiroshi Koga et al.   Nature Communications

HSC70 blockade by the therapeutic peptide P140 affects autophagic processes and endogenous MHCII presentation in murine lupus

(2010) N. Page et al.   ANNALS OF THE RHEUMATIC DISEASES

Lysosomal Proteolysis and Autophagy Require Presenilin 1 and Are Disrupted by Alzheimer-Related PS1 Mutations

(2010) Ju-Hyun Lee et al.   CELL

Identification of Regulators of Chaperone-Mediated Autophagy

(2010) Urmi Bandyopadhyay et al.   MOLECULAR CELL

The HSP70 chaperone machinery: J proteins as drivers of functional specificity

(2010) Harm H. Kampinga et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Characterization of artificially generated PbS aerosols and their use within a respiratory bioaccessibility test

(2009) Michael Philip Beeston et al.   ANALYST

Chaperone-mediated autophagy in health and disease

(2009) Maria Kon et al.   FEBS LETTERS

Chemical Manipulation of Hsp70 ATPase Activity Regulates Tau Stability

(2009) U. K. Jinwal et al.   JOURNAL OF NEUROSCIENCE

Crystal structure of human spliceosomal U1 snRNP at 5.5 Å resolution

(2009) Daniel A. Pomeranz Krummel et al.   NATURE

The Spliceosomal Phosphopeptide P140 Controls the Lupus Disease by Interacting with the HSC70 Protein and via a Mechanism Mediated by γδ T Cells

(2009) Nicolas Page et al.   PLoS One

Spliceosomal peptide P140 for immunotherapy of systemic lupus erythematosus: Results of an early phase II clinical trial

(2008) Sylviane Muller et al.   ARTHRITIS AND RHEUMATISM

Apoptosis-linked changes in the phosphorylation status and subcellular localization of the spliceosomal autoantigen U1-70K

(2008) J Dieker et al.   CELL DEATH AND DIFFERENTIATION

The Chaperone-Mediated Autophagy Receptor Organizes in Dynamic Protein Complexes at the Lysosomal Membrane

(2008) U. Bandyopadhyay et al.   MOLECULAR AND CELLULAR BIOLOGY