Keratin 80 promotes migration and invasion of colorectal carcinoma by interacting with PRKDC via activating the AKT pathway

DNA-dependent protein kinase catalytic subunit functions in metastasis and influences survival in advanced-stage laryngeal squamous cell carcinoma

(2017) Sha-sha He et al.   Journal of Cancer

Keratin 8-deletion induced colitis predisposes to murine colorectal cancer enforced by the inflammasome and IL-22 pathway

(2016) Julia O. Misiorek et al.   CARCINOGENESIS

Keratin 7 expression in lymph node metastases but not in the primary tumour correlates with distant metastases and poor prognosis in colon carcinoma

(2016) Piotr Czapiewski et al.   POLISH JOURNAL OF PATHOLOGY

Variable expression levels of keratin and vimentin reveal differential EMT status of circulating tumor cells and correlation with clinical characteristics and outcome of patients with metastatic breast cancer

(2015) Hara Polioudaki et al.   BMC CANCER

DNA-PKcs-Mediated Transcriptional Regulation Drives Prostate Cancer Progression and Metastasis

(2015) Jonathan F. Goodwin et al.   CANCER CELL

Silencing β3 Integrin by Targeted ECO/siRNA Nanoparticles Inhibits EMT and Metastasis of Triple-Negative Breast Cancer

(2015) Jenny G. Parvani et al.   CANCER RESEARCH

Mechanical and biological properties of oxidized horn keratin

(2015) Quanbin Zhang et al.   Materials Science & Engineering C-Materials for Biological Applications

Relationship between HER-2, COX-2, p53 and clinicopathologic features in gastric adenocarcinoma. Do these biomarkers have any prognostic significance?

(2015) Nesrin Ugras et al.   Turkish Journal of Gastroenterology

Baicalein inhibits the migration and invasion of colorectal cancer cells via suppression of the AKT signaling pathway

(2015) XIAOJIANG RUI et al.   Oncology Letters

DNA-PKcs is important for Akt activation and gemcitabine resistance in PANC-1 pancreatic cancer cells

(2014) Hao Hu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The novel AKT inhibitor afuresertib shows favorable safety, pharmacokinetics, and clinical activity in multiple myeloma

(2014) A. Spencer et al.   BLOOD

Andrographolide reduces proliferation and migration of lens epithelial cells by modulating PI3K/Akt pathway

(2014) Forum Kayastha et al.   EXPERIMENTAL EYE RESEARCH

DNA-PKcs deficiency sensitizes the human hepatoma HepG2 cells to cisplatin and 5-fluorouracil through suppression of the PI3K/Akt/NF-κB pathway

(2014) Yuan Fang et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Suppression of DNA-dependent protein kinase sensitize cells to radiation without affecting DSB repair

(2014) Ann-Sofie Gustafsson et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

EBV-miR-BART7-3p promotes the EMT and metastasis of nasopharyngeal carcinoma cells by suppressing the tumor suppressor PTEN

(2014) L-M Cai et al.   ONCOGENE

FOXC2 promotes colorectal cancer metastasis by directly targeting MET

(2014) Y-M Cui et al.   ONCOGENE

Activation of phosphatidylinositol 3-kinase/Akt signaling mediates sorafenib-induced invasion and metastasis in hepatocellular carcinoma

(2014) HAIYONG WANG et al.   ONCOLOGY REPORTS

A novel biomarker Linc00974 interacting with KRT19 promotes proliferation and metastasis in hepatocellular carcinoma

(2014) J Tang et al.   Cell Death & Disease

DNA-PK inhibition by NU7441 sensitizes breast cancer cells to ionizing radiation and doxorubicin

(2013) Wojciech M. Ciszewski et al.   BREAST CANCER RESEARCH AND TREATMENT

Keratin 19: a key role player in the invasion of human hepatocellular carcinomas

(2013) Olivier Govaere et al.   GUT

Inhibition of Snail1-DNA-PKcs Protein-Protein Interface Sensitizes Cancer Cells and Inhibits Tumor Metastasis

(2013) Ga-Young Kang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Keratin 8 and 18 Loss in Epithelial Cancer Cells Increases Collective Cell Migration and Cisplatin Sensitivity through Claudin1 Up-regulation

(2013) Anne-Marie Fortier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Scribble regulates an EMT polarity pathway through modulation of MAPK-ERK signaling to mediate junction formation

(2013) I. A. Elsum et al.   JOURNAL OF CELL SCIENCE

Keratins

(2012) Pavel Strnad et al.   CURRENT OPINION IN GASTROENTEROLOGY

Expression of cytokeratin 19 and matrix metalloproteinase 2 predicts lymph node metastasis in hepatocellular carcinoma

(2010) Zuo-Lin Xiang et al.   MOLECULAR BIOLOGY REPORTS

Suppression of DNA-PKcs enhances FGF-2 dependent human endothelial cell proliferation via negative regulation of Akt

(2009) Hanna Mannell et al.   CELLULAR SIGNALLING

Toward unraveling the complexity of simple epithelial keratins in human disease

(2009) M. Bishr Omary et al.   JOURNAL OF CLINICAL INVESTIGATION