BAG3 regulates stability of IL-8 mRNA via interplay between HuR and miR-4312 in PDACs

Cytoplasmic HuR Status Predicts Disease-free Survival in Resected Pancreatic Cancer

(2018) Talar Tatarian et al.   ANNALS OF SURGERY

BAG3 directly stabilizes Hexokinase 2 mRNA and promotes aerobic glycolysis in pancreatic cancer cells

(2017) Ming-Xin An et al.   JOURNAL OF CELL BIOLOGY

Cytoplasmic overexpression of RNA-binding protein HuR is a marker of poor prognosis in meningioma, and HuR knockdown decreases meningioma cell growth and resistance to hypoxia

(2017) Guillaume Gauchotte et al.   JOURNAL OF PATHOLOGY

RNA-binding protein HuR promotes bladder cancer progression by competitively binding to the long noncoding HOTAIR with miR-1

(2017) Dapeng Yu et al.   OncoTargets and Therapy

Regulation of nucleolin expression by miR-194, miR-206, and HuR

(2016) Sudeep Bose et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

H19Long Noncoding RNA Regulates Intestinal Epithelial Barrier Function via MicroRNA 675 by Interacting with RNA-Binding Protein HuR

(2016) Tongtong Zou et al.   MOLECULAR AND CELLULAR BIOLOGY

IL-8–Positive Tumor-Infiltrating Inflammatory Cells Are a Novel Prognostic Marker in Pancreatic Ductal Adenocarcinoma Patients

(2016) Yuan Fang et al.   PANCREAS

Cytokines as Biomarkers of Pancreatic Ductal Adenocarcinoma: A Systematic Review

(2016) Yandiswa Yolanda Yako et al.   PLoS One

Interplay between RNA-binding protein HuR and microRNA-125b regulates p53 mRNA translation in response to genotoxic stress

(2016) Deepika Ahuja et al.   RNA Biology

Posttranscriptional Regulation of the Inflammatory Marker C-Reactive Protein by the RNA-Binding Protein HuR and MicroRNA 637

(2015) Yoonseo Kim et al.   MOLECULAR AND CELLULAR BIOLOGY

RNA-binding protein HuR sequesters microRNA-21 to prevent translation repression of proinflammatory tumor suppressor gene programmed cell death 4

(2015) D K Poria et al.   ONCOGENE

BAG3 regulates cell proliferation, migration, and invasion in human colorectal cancer

(2015) Huiyong Shi et al.   TUMOR BIOLOGY

Estrogen receptor α regulates non-canonical autophagy that provides stress resistance to neuroblastoma and breast cancer cells and involves BAG3 function

(2015) V Felzen et al.   Cell Death & Disease

Targeting the mRNA-binding protein HuR impairs malignant characteristics of pancreatic ductal adenocarcinoma cells

(2015) Masaya Jimbo et al.   Oncotarget

Hsp70 in cancer: back to the future

(2014) M Y Sherman et al.   ONCOGENE

Cytoplasmic expression of HuR may be a valuable diagnostic tool for determining the potential for malignant transformation of oral verrucous borderline lesions

(2014) UMMA HABIBA et al.   ONCOLOGY REPORTS

BAG3 protein expression in melanoma metastatic lymph nodes correlates with patients’ survival

(2014) L Guerriero et al.   Cell Death & Disease

BAG3 is upregulated by c-Jun and stabilizes JunD

(2013) Chao Li et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Predictive and prognostic significance of cytoplasmic expression of ELAV-like protein HuR in invasive breast cancer treated with neoadjuvant chemotherapy

(2013) Jun Wang et al.   BREAST CANCER RESEARCH AND TREATMENT

Inflammatory cytokines in human pancreatic cancer

(2013) Rozita Roshani et al.   CANCER LETTERS

Retinoic acid-induced HOXA5 expression is co-regulated by HuR and miR-130a

(2013) Fan Yang et al.   CELLULAR SIGNALLING

TRAIL-induced expression of uPA and IL-8 strongly enhanced by overexpression of TRAF2 and Bcl-xL in pancreatic ductal adenocarcinoma cells

(2013) Dong-Hui Zhou et al.   Hepatobiliary & Pancreatic Diseases International

The interplay of HuR and miR-3134 in regulation of AU rich transcriptome

(2013) Shivani Sharma et al.   RNA Biology

Cytoplasmic expression of the ELAV-like protein HuR as a potential prognostic marker in esophageal squamous cell carcinoma

(2013) Cong Zhang et al.   TUMOR BIOLOGY

Cytoplasmic HuR expression correlates with P-gp, HER-2 positivity, and poor outcome in breast cancer

(2013) Zhongpeng Zhu et al.   TUMOR BIOLOGY

HuR and miR-1192 regulate myogenesis by modulating the translation of HMGB1 mRNA

(2013) Virginie Dormoy-Raclet et al.   Nature Communications

BAG3 Protein Is Overexpressed in Human Glioblastoma and Is a Potential Target for Therapy

(2011) Michelina Festa et al.   AMERICAN JOURNAL OF PATHOLOGY

Isoeugenol destabilizes IL-8 mRNA expression in THP-1 cells through induction of the negative regulator of mRNA stability tristetraprolin

(2011) Valentina Galbiati et al.   ARCHIVES OF TOXICOLOGY

BAG3 (BCL2-associated athanogene 3) interacts with MMP-2 to positively regulate invasion by ovarian carcinoma cells

(2011) Miwa Suzuki et al.   CANCER LETTERS

Competitive Regulation of Nucleolin Expression by HuR and miR-494

(2011) K. Tominaga et al.   MOLECULAR AND CELLULAR BIOLOGY

The mRNA Stability Factor HuR Inhibits MicroRNA-16 Targeting of COX-2

(2011) L. E. Young et al.   MOLECULAR CANCER RESEARCH

Regulation of mRNA Translation and Stability by microRNAs

(2010) Marc Robert Fabian et al.   Annual Review of Biochemistry

BAG3 directly associates with guanine nucleotide exchange factor of Rap1, PDZGEF2, and regulates cell adhesion

(2010) Masahiro Iwasaki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Interplay between microRNAs and RNA-binding proteins determines developmental processes

(2010) Martijn Kedde et al.   CELL CYCLE

Cytoplasmic Accumulation of the RNA-binding Protein HuR Stabilizes the Ornithine Decarboxylase Transcript in a Murine Nonmelanoma Skin Cancer Model

(2010) Shannon L. Nowotarski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The expression of IL-8 and IL-8 receptors in pancreatic adenocarcinomas and pancreatic neuroendocrine tumours

(2009) Farah Hussain et al.   CYTOKINE

AUF1 and HuR Proteins Stabilize Interleukin-8 mRNA in Human Saliva

(2009) V. Palanisamy et al.   JOURNAL OF DENTAL RESEARCH

Genomic and phenotypic analysis reveals a key role for CCN1 (CYR61) in BAG3-modulated adhesion and invasion

(2009) Jareer N Kassis et al.   JOURNAL OF PATHOLOGY

HuR/ELAVL1 RNA binding protein modulates interleukin-8 induction by muco-active ribotoxin deoxynivalenol

(2009) Hye Jin Choi et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Pancreatic Cancer

(2008) Anirban Maitra et al.   Annual Review of Pathology-Mechanisms of Disease

Diverse molecular functions of Hu proteins

(2008) M. N. Hinman et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Nuclear HuR accumulation through phosphorylation by Cdk1

(2008) H. H. Kim et al.   GENES & DEVELOPMENT

Posttranslational Modification of the AU-Rich Element Binding Protein HuR by Protein Kinase C  Elicits Angiotensin II-Induced Stabilization and Nuclear Export of Cyclooxygenase 2 mRNA

(2008) A. Doller et al.   MOLECULAR AND CELLULAR BIOLOGY