Endocytosis of synaptic ADAM10 in neuronal plasticity and Alzheimer’s disease

Tetraspanin15 regulates cellular trafficking and activity of the ectodomain sheddase ADAM10

(2012) Johannes Prox et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Alpha-Secretase Cleavage of the Amyloid Precursor Protein: Proteolysis Regulated by Signaling Pathways and Protein Trafficking

(2012) Stefan F. Lichtenthaler   Current Alzheimer Research

The neuropeptide PACAP38 induces dendritic spine remodeling through ADAM10-N-cadherin signaling pathway

(2012) F. Gardoni et al.   JOURNAL OF CELL SCIENCE

Clathrin-mediated endocytic proteins are upregulated in the cortex of the Tg2576 mouse model of Alzheimer’s disease-like amyloid pathology

(2011) Rhian S. Thomas et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Surface expression and limited proteolysis of ADAM10 are increased by a dominant negative inhibitor of dynamin

(2011) Robyn M Carey et al.   BMC CELL BIOLOGY

Dendritic spine pathology in neuropsychiatric disorders

(2011) Peter Penzes et al.   NATURE NEUROSCIENCE

Molecular mechanism and physiological functions of clathrin-mediated endocytosis

(2011) Harvey T. McMahon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Functional Links Between A  Toxicity, Endocytic Trafficking, and Alzheimer's Disease Risk Factors in Yeast

(2011) S. Treusch et al.   SCIENCE

Blocking ADAM10 synaptic trafficking generates a model of sporadic Alzheimer’s disease

(2010) Roberta Epis et al.   BRAIN

ADAM10 is the physiologically relevant, constitutive α-secretase of the amyloid precursor protein in primary neurons

(2010) Peer-Hendrik Kuhn et al.   EMBO JOURNAL

Genome-wide Analysis of Genetic Loci Associated With Alzheimer Disease

(2010) Sudha Seshadri   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

An Arginine Stretch Limits ADAM10 Exit from the Endoplasmic Reticulum

(2010) Elena Marcello et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synaptic Localization and Activity of ADAM10 Regulate Excitatory Synapses through N-Cadherin Cleavage

(2010) M. Malinverno et al.   JOURNAL OF NEUROSCIENCE

SAP97-mediated local trafficking is altered in Alzheimer disease patients' hippocampus

(2010) Elena Marcello et al.   NEUROBIOLOGY OF AGING

Superpose3D: A Local Structural Comparison Program That Allows for User-Defined Structure Representations

(2010) Pier Federico Gherardini et al.   PLoS One

The role of SAP97 in synaptic glutamate receptor dynamics

(2010) MacKenzie A. Howard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural dynamics of dendritic spines in memory and cognition

(2010) Haruo Kasai et al.   TRENDS IN NEUROSCIENCES

ADAM10, the Rate-limiting Protease of Regulated Intramembrane Proteolysis of Notch and Other Proteins, Is Processed by ADAMS-9, ADAMS-15, and the γ-Secretase

(2009) Thomas Tousseyn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A disintegrin and metalloproteinase (ADAM)-mediated ectodomain shedding of ADAM10

(2009) Edward Parkin et al.   JOURNAL OF NEUROCHEMISTRY

Synaptic Activity Reduces Intraneuronal A , Promotes APP Transport to Synapses, and Protects against A -Related Synaptic Alterations

(2009) D. Tampellini et al.   JOURNAL OF NEUROSCIENCE

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

(2009) Jean-Charles Lambert et al.   NATURE GENETICS

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

(2009) Denise Harold et al.   NATURE GENETICS

Glutamate Receptor Dynamics in Dendritic Microdomains

(2008) Thomas M. Newpher et al.   NEURON

Postsynaptic density–membrane associated guanylate kinase proteins (PSD–MAGUKs) and their role in CNS disorders

(2008) F. Gardoni et al.   NEUROSCIENCE

The good, the bad and the ugly substrates for ADAM10 and ADAM17 in brain pathology, inflammation and cancer

(2008) Jessica Pruessmeyer et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY