P42 Ebp1 regulates the proteasomal degradation of the p85 regulatory subunit of PI3K by recruiting a chaperone-E3 ligase complex HSP70/CHIP

Metastatic Lymph Node CHIP Expression is a Potential Prognostic Marker for Resected Esophageal Squamous Cell Carcinoma Patients

(2013) Jing Wen et al.   ANNALS OF SURGICAL ONCOLOGY

Inhibition of Histone Deacetylase Activity Suppresses IFN-  Induction of Tripartite Motif 22 via CHIP-Mediated Proteasomal Degradation of IRF-1

(2013) B. Gao et al.   JOURNAL OF IMMUNOLOGY

A comprehensive immunohistochemical and molecular approach to the PI3K/AKT/mTOR (phosphoinositide 3-kinase/v-akt murine thymoma viral oncogene/mammalian target of rapamycin) pathway in bladder urothelial carcinoma

(2012) Penelope Korkolopoulou et al.   BJU INTERNATIONAL

Activation of PI3K/Akt signaling by n-terminal SH2 domain mutants of the p85α regulatory subunit of PI3K is enhanced by deletion of its c-terminal SH2 domain

(2012) Bianca T. Hofmann et al.   CELLULAR SIGNALLING

C-terminal phosphorylation of Hsp70 and Hsp90 regulates alternate binding to co-chaperones CHIP and HOP to determine cellular protein folding/degradation balances

(2012) P Muller et al.   ONCOGENE

Androgen receptor degradation by the E3 ligase CHIP modulates mitotic arrest in prostate cancer cells

(2012) S Sarkar et al.   ONCOGENE

Synergistic efficacy of LBH and αB-crystallin through inhibiting transcriptional activities of p53 and p21

(2011) Yun Deng et al.   BMB Reports

Attenuation of β-amyloid-induced neuroinflammation by KHG21834 in vivo

(2011) Eun-A Kim et al.   BMB Reports

Long isoform of ErbB3 binding protein, p48, mediates protein kinase B/Akt-dependent HDM2 stabilization and nuclear localization

(2011) Chung Kwon Kim et al.   EXPERIMENTAL CELL RESEARCH

Suppression of the PI3K subunit p85α delays embryoid body development and inhibits cell adhesion

(2011) Susan M.R. Gurney et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The mammalian target of rapamycin pathway is widely activated without PTEN deletion in renal cell carcinoma metastases

(2010) Tamer Abou Youssif et al.   CANCER

Negative Regulation of p53 by the Long Isoform of ErbB3 Binding Protein Ebp1 in Brain Tumors

(2010) C. K. Kim et al.   CANCER RESEARCH

Oligodeoxynucleotide IMT504 induces a marked recovery in a streptozotocin-induced model of diabetes in rats: correlation with an early increase in the expression of nestin and neurogenin 3 progenitor cell markers

(2010) M. S. Bianchi et al.   DIABETOLOGIA

Inhibition of heregulin mediated MCF-7 breast cancer cell growth by the ErbB3 binding protein EBP1

(2008) Yuexing Zhang et al.   CANCER LETTERS

Human BRE1 Is an E3 Ubiquitin Ligase for Ebp1 Tumor Suppressor

(2008) Zhixue Liu et al.   MOLECULAR BIOLOGY OF THE CELL

Phosphoinositide 3-OH kinase p85α and p110β are essential for androgen receptor transactivation and tumor progression in prostate cancers

(2008) Q Zhu et al.   ONCOGENE

An Integrated Genomic Analysis of Human Glioblastoma Multiforme

(2008) D. W. Parsons et al.   SCIENCE