Severe hypoxia induces complete antifolate resistance in carcinoma cells due to cell cycle arrest

Chemotherapeutic Drug-Induced ABCG2 Promoter Demethylation as a Novel Mechanism of Acquired Multidrug Resistance

(2015) Eran E. Bram et al.   NEOPLASIA

Cancer chemotherapy: A critical analysis of its 60 years of history

(2012) Darío Galmarini et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Antifolates in cancer therapy: Structure, activity and mechanisms of drug resistance

(2012) Nitzan Gonen et al.   DRUG RESISTANCE UPDATES

Serum Starvation Induced Cell Cycle Synchronization Facilitates Human Somatic Cells Reprogramming

(2012) Mengfei Chen et al.   PLoS One

ATM-mediated phosphorylation of polynucleotide kinase/phosphatase is required for effective DNA double-strand break repair

(2011) Hava Segal-Raz et al.   EMBO REPORTS

Visualizing the effect of hypoxia on fluorescence kinetics in living HeLa cells using the fluorescent ubiquitination-based cell cycle indicator (Fucci)

(2011) Atsushi Kaida et al.   EXPERIMENTAL CELL RESEARCH

Alcohol-associated folate disturbances result in altered methylation of folate-regulating genes

(2011) Nissar Ahmad Wani et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Therapeutic Targeting of a Novel 6-Substituted Pyrrolo [2,3-d]pyrimidine Thienoyl Antifolate to Human Solid Tumors Based on Selective Uptake by the Proton-Coupled Folate Transporter

(2011) S. Kugel Desmoulin et al.   MOLECULAR PHARMACOLOGY

Reduced TIMP-2 in hypoxia enhances angiogenesis

(2010) Nitza Lahat et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Targeting the Proton-Coupled Folate Transporter for Selective Delivery of 6-Substituted Pyrrolo[2,3-d]Pyrimidine Antifolate Inhibitors of De Novo Purine Biosynthesis in the Chemotherapy of Solid Tumors

(2010) S. K. Desmoulin et al.   MOLECULAR PHARMACOLOGY

Functional elements in the minimal promoter of the human proton-coupled folate transporter

(2009) Michal Stark et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Nucleoside Transporter Proteins

(2009) Miriam Molina-Arcas et al.   Current Vascular Pharmacology

PCFT/SLC46A1 promoter methylation and restoration of gene expression in human leukemia cells

(2008) Nitzan Gonen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Preferential Cytotoxicity of Bortezomib toward Hypoxic Tumor Cells via Overactivation of Endoplasmic Reticulum Stress Pathways

(2008) D. R. Fels et al.   CANCER RESEARCH

Hypoxia-Inducible Factor–Dependent Repression of Equilibrative Nucleoside Transporter 2 Attenuates Mucosal Inflammation During Intestinal Hypoxia

(2008) Julio C. Morote–Garcia et al.   GASTROENTEROLOGY