Centrosome-declustering drugs mediate a two-pronged attack on interphase and mitosis in supercentrosomal cancer cells

Oncogene-like induction of cellular invasion from centrosome amplification

(2014) Susana A. Godinho et al.   NATURE

Quantitative multi-parametric evaluation of centrosome declustering drugs: centrosome amplification, mitotic phenotype, cell cycle and death

(2014) A Ogden et al.   Cell Death & Disease

Dissecting Paclitaxel–Microtubule Association: Quantitative Assessment of the 2′-OH Group

(2013) Shubhada Sharma et al.   BIOCHEMISTRY

Interphase microtubules: chief casualties in the war on cancer?

(2013) Angela Ogden et al.   DRUG DISCOVERY TODAY

Comparison of Methods for Proliferative Index Analysis for Grading Pancreatic Well-Differentiated Neuroendocrine Tumors

(2012) Pamela P. Goodell et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Heading off with the herd: how cancer cells might maneuver supernumerary centrosomes for directional migration

(2012) Angela Ogden et al.   CANCER AND METASTASIS REVIEWS

GF-15, a Novel Inhibitor of Centrosomal Clustering, Suppresses Tumor Cell Growth In Vitro and In Vivo

(2012) M. S. Raab et al.   CANCER RESEARCH

Let's huddle to prevent a muddle: centrosome declustering as an attractive anticancer strategy

(2012) A Ogden et al.   CELL DEATH AND DIFFERENTIATION

A Clinical Overview of Centrosome Amplification in Human Cancers

(2012) Jason Yongsheng Chan   International Journal of Biological Sciences

Induction of robust de novo centrosome amplification, high-grade spindle multipolarity and metaphase catastrophe: a novel chemotherapeutic approach

(2012) V Pannu et al.   Cell Death & Disease

A phenanthrene derived PARP inhibitor is an extra-centrosomes de-clustering agent exclusively eradicating human cancer cells

(2011) Asher Castiel et al.   BMC CANCER

Disconnecting the Golgi ribbon from the centrosome prevents directional cell migration and ciliogenesis

(2011) Lidia Hurtado et al.   JOURNAL OF CELL BIOLOGY

Mitosis is not a key target of microtubule agents in patient tumors

(2011) Edina Komlodi-Pasztor et al.   Nature Reviews Clinical Oncology

A novel microtubule-modulating noscapinoid triggers apoptosis by inducing spindle multipolarity via centrosome amplification and declustering

(2010) P Karna et al.   CELL DEATH AND DIFFERENTIATION

Induction of Reactive Oxygen Species-mediated Autophagy by a Novel Microtubule-modulating Agent

(2010) Prasanthi Karna et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An Intact Centrosome Is Required for the Maintenance of Polarization during Directional Cell Migration

(2010) Nicole M. Wakida et al.   PLoS One

Short exposure to paclitaxel induces multipolar spindle formation and aneuploidy through promotion of acentrosomal pole assembly

(2010) MingLei Bian et al.   Science China-Life Sciences

Centrioles, Centrosomes, and Cilia in Health and Disease

(2009) Erich A. Nigg et al.   CELL