Caveolin-1 is required for TGF- β -induced transactivation of the EGF receptor pathway in hepatocytes through the activation of the metalloprotease TACE/ADAM17

Distinct dedifferentiation processes affect caveolin-1 expression in hepatocytes

(2013) Christoph Meyer et al.   Cell Communication and Signaling

Overactivation of the TGF-β pathway confers a mesenchymal-like phenotype and CXCR4-dependent migratory properties to liver tumor cells

(2013) Esther Bertran et al.   HEPATOLOGY

Caveolin and TGF-β entanglements

(2013) Christoph Meyer et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Internalization Mechanisms of the Epidermal Growth Factor Receptor after Activation with Different Ligands

(2013) Lasse Henriksen et al.   PLoS One

Controlling Long-Term Signaling: Receptor Dynamics Determine Attenuation and Refractory Behavior of the TGF-  Pathway

(2013) P. Vizan et al.   Science Signaling

Caveolin-1 abrogates TGF-β mediated hepatocyte apoptosis

(2013) C Meyer et al.   Cell Death & Disease

Post-translational regulation of TGF-β receptor and Smad signaling

(2012) Pinglong Xu et al.   FEBS LETTERS

TGFβ signalling in context

(2012) Joan Massagué   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Caveolin-1 orchestrates the balance between glucose and lipid-dependent energy metabolism: Implications for liver regeneration

(2011) Manuel Alejandro Fernández-Rojo et al.   HEPATOLOGY

Caveolin-1 overexpression is associated with hepatocellular carcinoma tumourigenesis and metastasis

(2011) Edith Yuk Ting Tse et al.   JOURNAL OF PATHOLOGY

Caveolin-1 is related to invasion, survival, and poor prognosis in hepatocellular cancer

(2011) Yu Tang et al.   MEDICAL ONCOLOGY

TGFβ induces proHB-EGF shedding and EGFR transactivation through ADAM activation in gastric cancer cells

(2010) Masahide Ebi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Ectodomain shedding of the Notch ligand Jagged1 is mediated by ADAM17, but is not a lipid-raft-associated event

(2010) Catherine A. Parr-Sturgess et al.   BIOCHEMICAL JOURNAL

Dissecting the effect of targeting the epidermal growth factor receptor on TGF-β-induced-apoptosis in human hepatocellular carcinoma cells

(2010) Laia Caja et al.   JOURNAL OF HEPATOLOGY

Distinct role of endocytosis for Smad and non-Smad TGF-β signaling regulation in hepatocytes

(2010) Christoph Meyer et al.   JOURNAL OF HEPATOLOGY

Caveolin-1 negatively regulates a metalloprotease-dependent epidermal growth factor receptor transactivation by angiotensin II

(2010) Akira Takaguri et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Caveolin-1 plays important role in EGF-induced migration and proliferation of mouse embryonic stem cells: involvement of PI3K/Akt and ERK

(2009) Jae Hong Park et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Transforming Growth Factor   Induces Clustering of HER2 and Integrins by Activating Src-Focal Adhesion Kinase and Receptor Association to the Cytoskeleton

(2009) S. E. Wang et al.   CANCER RESEARCH

Impairment of Transforming Growth Factor β Signaling in Caveolin-1-deficient Hepatocytes

(2009) Rafael Mayoral et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Compartmentalization of epidermal growth factor receptor in liver plasma membrane

(2009) Ye Wang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The inhibition of the epidermal growth factor (EGF) pathway enhances TGF-β-induced apoptosis in rat hepatoma cells through inducing oxidative stress coincident with a change in the expression pattern of the NADPH oxidases (NOX) isoforms

(2008) Patricia Sancho et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

TGFβ in Cancer

(2008) Joan Massagué   CELL

Endocytic regulation of TGF-β signaling

(2008) Ye-Guang Chen   CELL RESEARCH

Upregulation of the NADPH oxidase NOX4 by TGF-beta in hepatocytes is required for its pro-apoptotic activity

(2008) Irene Carmona-Cuenca et al.   JOURNAL OF HEPATOLOGY

Transforming Growth Factor   Engages TACE and ErbB3 To Activate Phosphatidylinositol-3 Kinase/Akt in ErbB2-Overexpressing Breast Cancer and Desensitizes Cells to Trastuzumab

(2008) S. E. Wang et al.   MOLECULAR AND CELLULAR BIOLOGY