ERO1α-dependent endoplasmic reticulum–mitochondrial calcium flux contributes to ER stress and mitochondrial permeabilization by procaspase-activating compound-1 (PAC-1)

BH3-only proteins are part of a regulatory network that control the sustained signalling of the unfolded protein response sensor IRE1α

(2012) Diego A Rodriguez et al.   EMBO JOURNAL

Hyperactivity of the Ero1α Oxidase Elicits Endoplasmic Reticulum Stress but No Broad Antioxidant Response

(2012) Henning Gram Hansen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endoplasmic reticulum–mitochondria contacts: function of the junction

(2012) Ashley A. Rowland et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Ero1α Regulates Ca2+ Fluxes at the Endoplasmic Reticulum–Mitochondria Interface (MAM)

(2011) Tiziana Anelli et al.   ANTIOXIDANTS & REDOX SIGNALING

The sarcoplasmic reticulum luminal thiol oxidase ERO1 regulates cardiomyocyte excitation-coupled calcium release and response to hemodynamic load

(2011) King-Tung Chin et al.   FASEB JOURNAL

Drug-induced Senescence Generates Chemoresistant Stemlike Cells with Low Reactive Oxygen Species

(2011) Santhi Achuthan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Real-time monitoring of redox changes in the mammalian endoplasmic reticulum

(2011) M. van Lith et al.   JOURNAL OF CELL SCIENCE

High Throughput Ratio Imaging to Profile Caspase Activity: Potential Application in Multiparameter High Content Apoptosis Analysis and Drug Screening

(2011) Jeena Joseph et al.   PLoS One

Essential requirement of cytochrome c release for caspase activation by procaspase-activating compound defined by cellular models

(2011) M Seervi et al.   Cell Death & Disease

Ubiquitylation in ERAD: Reversing to Go Forward?

(2011) Yien Che Tsai et al.   PLOS BIOLOGY

Glucose regulated protein 78 (GRP78) is overexpressed in colorectal carcinoma and regulates colorectal carcinoma cell growth and apoptosis

(2010) Xiaoming Xing et al.   ACTA HISTOCHEMICA

CHOP and AP-1 cooperatively mediate PUMA expression during lipoapoptosis

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Molecular Mechanisms Regulating Oxidative Activity of the Ero1 Family in the Endoplasmic Reticulum

(2010) Timothy J. Tavender et al.   ANTIOXIDANTS & REDOX SIGNALING

Bax deficiency mediated drug resistance can be reversed by endoplasmic reticulum stress induced death signaling

(2010) Bhavya Balan Chandrika et al.   BIOCHEMICAL PHARMACOLOGY

Discovery and Canine Preclinical Assessment of a Nontoxic Procaspase-3-Activating Compound

(2010) Q. P. Peterson et al.   CANCER RESEARCH

Ero1α requires oxidizing and normoxic conditions to localize to the mitochondria-associated membrane (MAM)

(2010) Susanna Y. Gilady et al.   CELL STRESS & CHAPERONES

Endoplasmic reticulum targeted Bcl2 confers long term cell survival through phosphorylation of heat shock protein 27

(2010) Bhavya Balan Chandrika et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Turning enzymes ON with small molecules

(2010) Julie A Zorn et al.   Nature Chemical Biology

Role of ERO1-α–mediated stimulation of inositol 1,4,5-triphosphate receptor activity in endoplasmic reticulum stress–induced apoptosis

(2009) Gang Li et al.   JOURNAL OF CELL BIOLOGY

Procaspase-3 Activation as an Anti-Cancer Strategy: Structure−Activity Relationship of Procaspase-Activating Compound 1 (PAC-1) and Its Cellular Co-Localization with Caspase-3

(2009) Quinn P. Peterson et al.   JOURNAL OF MEDICINAL CHEMISTRY

PAC-1 Activates Procaspase-3 in Vitro through Relief of Zinc-Mediated Inhibition

(2009) Quinn P. Peterson et al.   JOURNAL OF MOLECULAR BIOLOGY

MAM: more than just a housekeeper

(2009) Teruo Hayashi et al.   TRENDS IN CELL BIOLOGY

Bcl-2 family proteins and cancer

(2008) K W Yip et al.   ONCOGENE