Pathogenic prions deviate PrPC signaling in neuronal cells and impair A-beta clearance

Estrogen activates matrix metalloproteinases-2 and -9 to increase beta amyloid degradation

(2012) Sara Merlo et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons

(2012) Ji Won Um et al.   NATURE NEUROSCIENCE

The cellular prion protein mediates neurotoxic signalling of β-sheet-rich conformers independent of prion replication

(2011) Ulrike K Resenberger et al.   EMBO JOURNAL

Cerebrospinal Fluid Markers in Sporadic Creutzfeldt-Jakob Disease

(2011) Gianluigi Zanusso et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Prion Protein Interacts with BACE1 Protein and Differentially Regulates Its Activity toward Wild Type and Swedish Mutant Amyloid Precursor Protein

(2011) Heledd H. Griffiths et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amyloid-β-induced Synapse Damage Is Mediated via Cross-linkage of Cellular Prion Proteins

(2011) Clive Bate et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amyloid-β42 Interacts Mainly with Insoluble Prion Protein in the Alzheimer Brain

(2011) Wen-Quan Zou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amyloid-beta oligomers increase the localization of prion protein at the cell surface

(2011) Fabiana A. Caetano et al.   JOURNAL OF NEUROCHEMISTRY

Prion protein in Alzheimer's pathogenesis: a hot and controversial issue

(2010) Iryna Benilova et al.   EMBO Molecular Medicine

Understanding the neurospecificity of Prion protein signaling

(2010) Benoit Schneider   Frontiers in Bioscience-Landmark

The role of lipid rafts in prion protein biology

(2010) Victoria Lewis   Frontiers in Bioscience-Landmark

Metzincin Proteases and Their Inhibitors: Foes or Friends in Nervous System Physiology?

(2010) S. Rivera et al.   JOURNAL OF NEUROSCIENCE

Prion infection of differentiated neurospheres

(2010) Maria Eugenia Herva et al.   JOURNAL OF NEUROSCIENCE METHODS

Prion protein and Alzheimer disease

(2010) Katherine A.B. Kellett et al.   Prion

Redox Control of Prion and Disease Pathogenesis

(2009) Neena Singh et al.   ANTIOXIDANTS & REDOX SIGNALING

Inhibition of cholesterol recycling impairs cellular PrPSc propagation

(2009) Sabine Gilch et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Inverse Regulation of Plasticity-related Immediate Early Genes by Calcineurin in Hippocampal Neurons

(2009) Brian Yee Hong Lam et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oral pravastatin prolongs survival time of scrapie-infected mice

(2009) V. Vetrugno et al.   JOURNAL OF GENERAL VIROLOGY

β-amyloid oligomers and cellular prion protein in Alzheimer’s disease

(2009) Erik C. Gunther et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Prions: Protein Aggregation and Infectious Diseases

(2009) Adriano Aguzzi et al.   PHYSIOLOGICAL REVIEWS

Sequestration of free cholesterol in cell membranes by prions correlates with cytoplasmic phospholipase A2 activation

(2008) Clive Bate et al.   BMC BIOLOGY

CREB-dependent gene regulation by prion protein: Impact on MMP-9 and β-dystroglycan

(2008) Elodie Pradines et al.   CELLULAR SIGNALLING

Stress-protective signalling of prion protein is corrupted by scrapie prions

(2008) Angelika S Rambold et al.   EMBO JOURNAL

Prions Impair Bioaminergic Functions through Serotonin- or Catecholamine-derived Neurotoxins in Neuronal Cells

(2008) Sophie Mouillet-Richard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of Erk1/2 activation in prion disease pathogenesis: Absence of CCR1 leads to increased Erk1/2 activation and accelerated disease progression

(2008) R LACASSE et al.   JOURNAL OF NEUROIMMUNOLOGY

Aggregated, Wild-Type Prion Protein Causes Neurological Dysfunction and Synaptic Abnormalities

(2008) R. Chiesa et al.   JOURNAL OF NEUROSCIENCE

Physiology of the Prion Protein

(2008) Rafael Linden et al.   PHYSIOLOGICAL REVIEWS