Pin1 modulates p63α protein stability in regulation of cell survival, proliferation and tumor formation

SENP1 deSUMOylates and Regulates Pin1 Protein Activity and Cellular Function

(2013) Chun-Hau Chen et al.   CANCER RESEARCH

DNA damage down-regulates ΔNp63α and induces apoptosis independent of wild type p53

(2012) Xiaorong Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The ubiquitin E3 ligase WWP1 decreases CXCL12-mediated MDA231 breast cancer cell migration and bone metastasis

(2012) Kristina Subik et al.   BONE

Recognition mechanism of p63 by the E3 ligase Itch

(2012) Alessia Bellomaria et al.   CELL CYCLE

p63 the guardian of human reproduction

(2012) Ivano Amelio et al.   CELL CYCLE

Retinoblastoma tumor-suppressor protein phosphorylation and inactivation depend on direct interaction with Pin1

(2012) F Rizzolio et al.   CELL DEATH AND DIFFERENTIATION

Negative Regulation of the Stability and Tumor Suppressor Function of Fbw7 by the Pin1 Prolyl Isomerase

(2012) Sang-Hyun Min et al.   MOLECULAR CELL

A Pin1/Mutant p53 Axis Promotes Aggressiveness in Breast Cancer

(2011) Javier E. Girardini et al.   CANCER CELL

Regulation of skin aging and heart development by TAp63

(2011) M Paris et al.   CELL DEATH AND DIFFERENTIATION

Tumor suppressive activity of prolyl isomerase Pin1 in renal cell carcinoma

(2011) Brian L. Teng et al.   Molecular Oncology

Prolyl isomerase Pin1 as a molecular switch to determine the fate of phosphoproteins

(2011) Yih-Cherng Liou et al.   TRENDS IN BIOCHEMICAL SCIENCES

Recognition of p63 by the E3 ligase ITCH: Effect of an ectodermal dysplasia mutant

(2010) Alessia Bellomaria et al.   CELL CYCLE

MDM2 and Fbw7 cooperate to induce p63 protein degradation following DNA damage and cell differentiation

(2010) F. Galli et al.   JOURNAL OF CELL SCIENCE

TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs

(2010) Xiaohua Su et al.   NATURE

p63 and p73, the Ancestors of p53

(2010) V. Dotsch et al.   Cold Spring Harbor Perspectives in Biology

The prolyl-isomerase Pin1 is a Notch1 target that enhances Notch1 activation in cancer

(2009) Alessandra Rustighi et al.   NATURE CELL BIOLOGY

TAp63 induces senescence and suppresses tumorigenesis in vivo

(2009) Xuecui Guo et al.   NATURE CELL BIOLOGY

Inhibition of the c-Abl–TAp63 pathway protects mouse oocytes from chemotherapy-induced death

(2009) Stefania Gonfloni et al.   NATURE MEDICINE

WW domain-containing E3 ubiquitin protein ligase 1 targets p63 transcription factor for ubiquitin-mediated proteasomal degradation and regulates apoptosis

(2008) Y Li et al.   CELL DEATH AND DIFFERENTIATION