Glucocorticoid-mediated BIM induction and apoptosis are regulated by Runx2 and c-Jun in leukemia cells

Glucocorticoid-Mediated Repression of the Oncogenic microRNA Cluster miR-17∼92 Contributes to the Induction of Bim and Initiation of Apoptosis

(2011) Jason K. Molitoris et al.   MOLECULAR ENDOCRINOLOGY

Wip1 promotes RUNX2-dependent apoptosis in p53-negative tumors and protects normal tissues during treatment with anticancer agents

(2011) A. R. Goloudina et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epigenetic silencing of BIM in glucocorticoid poor-responsive pediatric acute lymphoblastic leukemia, and its reversal by histone deacetylase inhibition

(2010) P. S. Bachmann et al.   BLOOD

Runx2 in normal tissues and cancer cells: A developing story

(2010) Karen Blyth et al.   BLOOD CELLS MOLECULES AND DISEASES

BIM is a prognostic biomarker for early prednisolone response in pediatric acute lymphoblastic leukemia

(2010) Nan Jiang et al.   EXPERIMENTAL HEMATOLOGY

Pro-apoptotic protein BIM in apoptosis of glucocorticoid-sensitive and -resistant acute lymphoblastic leukemia CEM cells

(2010) Ya-ning Zhao et al.   MEDICAL ONCOLOGY

The BCL-2 Family Reunion

(2010) Jerry E. Chipuk et al.   MOLECULAR CELL

Repression of the BH3-only molecule PMAIP1/Noxa impairs glucocorticoid sensitivity of acute lymphoblastic leukemia cells

(2009) Christian Ploner et al.   APOPTOSIS

Runx1 Is a Co-activator with FOXO3 to Mediate Transforming Growth Factor β (TGFβ)-induced Bim Transcription in Hepatic Cells

(2009) Gary M. Wildey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MEK inhibitors potentiate dexamethasone lethality in acute lymphoblastic leukemia cells through the pro-apoptotic molecule BIM

(2009) A A Rambal et al.   LEUKEMIA

p38 MAP kinase mediates arsenite-induced apoptosis through FOXO3a activation and induction of Bim transcription

(2008) Beibei Cai et al.   APOPTOSIS

Runx2-mediated activation of the Bax gene increases osteosarcoma cell sensitivity to apoptosis

(2008) R A Eliseev et al.   ONCOGENE

The BCL-2 protein family: opposing activities that mediate cell death

(2007) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY