Apoptosis, autophagy and ER stress in mevalonate cascade inhibition-induced cell death of human atrial fibroblasts

Geranylgeranyl transferase 1 modulates autophagy and apoptosis in human airway smooth muscle

(2011) Saeid Ghavami et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The unfolded protein response and proteostasis in Alzheimer disease

(2011) Wiep Scheper et al.   Autophagy

Targeting autophagy enhances sorafenib lethality for hepatocellular carcinoma via ER stress-related apoptosis

(2011) Ying-Hong Shi et al.   Autophagy

cAMP induces autophagy via a novel pathway involving ERK, cyclin E and Beclin 1

(2011) Hege Ugland et al.   Autophagy

Atorvastatin induces autophagy in prostate cancer PC3 cells through activation ofLC3transcription

(2011) Nicholas Toepfer et al.   CANCER BIOLOGY & THERAPY

Direct cytotoxicity produced by adenoviral-mediated interferon α gene transfer in interferon-resistant cancer cells involves ER stress and caspase 4 activation

(2011) Z Yang et al.   CANCER GENE THERAPY

Targeting cathepsin S induces tumor cell autophagy via the EGFR–ERK signaling pathway

(2011) Kuo-Li Chen et al.   CANCER LETTERS

Statins and myocardial remodelling: cell and molecular pathways

(2011) Karen E. Porter et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

A New Autophagy-related Checkpoint in the Degradation of an ERAD-M Target

(2011) Edith Kario et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Caspase-4 Directly Activates Caspase-9 in Endoplasmic Reticulum Stress–Induced Apoptosis in SH-SY5Y Cells

(2011) Akiko Yamamuro et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

The Unfolded Protein Response: Integrating Stress Signals Through the Stress Sensor IRE1α

(2011) Claudio Hetz et al.   PHYSIOLOGICAL REVIEWS

Mevalonate Cascade Regulation of Airway Mesenchymal Cell Autophagy and Apoptosis: A Dual Role for p53

(2011) Saeid Ghavami et al.   PLoS One

Autophagy Interplay with Apoptosis and Cell Cycle Regulation in the Growth Inhibiting Effect of Resveratrol in Glioma Cells

(2011) Eduardo C. Filippi-Chiela et al.   PLoS One

Induction of ER stress in response to oxygen-glucose deprivation of cortical cultures involves the activation of the PERK and IRE-1 pathways and of caspase-12

(2011) N Badiola et al.   Cell Death & Disease

Antifibrotic properties of c-Ski and its regulation of cardiac myofibroblast phenotype and contractility

(2010) Ryan H. Cunnington et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Cardioprotection by Endoplasmic Reticulum Stress–Induced Autophagy

(2010) Goran Petrovski et al.   ANTIOXIDANTS & REDOX SIGNALING

A novel statin-mediated “prenylation block-and-release” assay provides insight into the membrane targeting mechanisms of small GTPases

(2010) Bassam R. Ali et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Statin-triggered cell death in primary human lung mesenchymal cells involves p53-PUMA and release of Smac and Omi but not cytochrome c

(2010) Saeid Ghavami et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Involvement of RhoA and RalB in geranylgeranyltransferase I inhibitor-mediated inhibition of proliferation and migration of human oral squamous cell carcinoma cells

(2010) Masakazu Hamada et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Effects of Statin Treatment on Cardiac Function in Patients With Chronic Heart Failure: A Meta-Analysis of Randomized Controlled Trials

(2010) Lei Zhang et al.   CLINICAL CARDIOLOGY

In search of an “autophagomometer”

(2009) David C. Rubinsztein et al.   Autophagy

Evidence that endoplasmic reticulum (ER) stress and caspase-4 activation occur in human neutrophils

(2009) François Binet et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Atorvastatin mediates increases in intralesional BAX and BAK expression in human end-stage abdominal aortic aneurysms

(2009) Morris Schweitzer et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

ER stress in Alzheimer's disease: a novel neuronal trigger for inflammation and Alzheimer's pathology

(2009) Antero Salminen et al.   Journal of Neuroinflammation

ERAD inhibitors integrate ER stress with an epigenetic mechanism to activate BH3-only protein NOXA in cancer cells

(2009) Q. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydrophobic statins induce autophagy in cultured human rhabdomyosarcoma cells

(2008) Makoto Araki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

HMG-CoA reductase inhibitors activate the unfolded protein response and induce cytoprotective GRP78 expression

(2008) Jui-Ching Chen et al.   CARDIOVASCULAR RESEARCH

The ATG12-Conjugating Enzyme ATG10 Is Essential for Autophagic Vesicle Formation in Arabidopsis thaliana

(2008) A. R. Phillips et al.   GENETICS

Inhibition of Cardiac Remodeling by Pravastatin Is Associated with Amelioration of Endoplasmic Reticulum Stress

(2008) Hui Zhao et al.   HYPERTENSION RESEARCH

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE