Allosteric Activation of Bacterial Response Regulators: the Role of the Cognate Histidine Kinase Beyond Phosphorylation

Visualizing autophosphorylation in histidine kinases

(2014) Patricia Casino et al.   Nature Communications

Segmental Helical Motions and Dynamical Asymmetry Modulate Histidine Kinase Autophosphorylation

(2014) Ariel E. Mechaly et al.   PLOS BIOLOGY

Crystal structure of the response regulator spr1814 from Streptococcus pneumoniae reveals unique interdomain contacts among NarL family proteins

(2013) Ae Kyung Park et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A Link between Dimerization and Autophosphorylation of the Response Regulator PhoB

(2013) Rachel L. Creager-Allen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Comprehensive Analysis of OmpR Phosphorylation, Dimerization, and DNA Binding Supports a Canonical Model for Activation

(2013) Christopher M. Barbieri et al.   JOURNAL OF MOLECULAR BIOLOGY

Phosphorylation-dependent conformational changes and domain rearrangements in Staphylococcus aureus VraR activation

(2013) P. G. Leonard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis of a Rationally Rewired Protein-Protein Interface Critical to Bacterial Signaling

(2013) Anna I. Podgornaia et al.   STRUCTURE

Cooperativity in Cellular Biochemical Processes: Noise-Enhanced Sensitivity, Fluctuating Enzyme, Bistability with Nonlinear Feedback, and Other Mechanisms for Sigmoidal Responses

(2012) Hong Qian   Annual Review of Biophysics

Solution Structure of a Complex of the Histidine Autokinase CheA with Its Substrate CheY

(2012) Guoya Mo et al.   BIOCHEMISTRY

Adaptive Mutations that Prevent Crosstalk Enable the Expansion of Paralogous Signaling Protein Families

(2012) Emily J. Capra et al.   CELL

Direct-coupling analysis of residue coevolution captures native contacts across many protein families

(2011) F. Morcos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis of Response Regulator Dephosphorylation by Rap Phosphatases

(2011) Vijay Parashar et al.   PLOS BIOLOGY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Molecular strategies for phosphorylation-mediated regulation of response regulator activity

(2010) Rong Gao et al.   CURRENT OPINION IN MICROBIOLOGY

Receiver domain structure and function in response regulator proteins

(2010) Robert B Bourret   CURRENT OPINION IN MICROBIOLOGY

Structural and Enzymatic Insights into the ATP Binding and Autophosphorylation Mechanism of a Sensor Histidine Kinase

(2010) Felipe Trajtenberg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Response Regulator Autophosphorylation through Interdomain Contacts

(2010) Christopher M. Barbieri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identical phosphatase mechanisms achieved through distinct modes of binding phosphoprotein substrate

(2010) Y. Pazy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Using Structural Information to Change the Phosphotransfer Specificity of a Two-Component Chemotaxis Signalling Complex

(2010) Christian H. Bell et al.   PLOS BIOLOGY

Biological Insights from Structures of Two-Component Proteins

(2009) Rong Gao et al.   Annual Review of Microbiology

Oligomerization of Bacillus subtilis DesR is required for fine tuning regulation of membrane fluidity

(2009) Sebastián R. Najle et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Transient Non-native Hydrogen Bonds Promote Activation of a Signaling Protein

(2009) Alexandra K. Gardino et al.   CELL

Structural Insight into Partner Specificity and Phosphoryl Transfer in Two-Component Signal Transduction

(2009) Patricia Casino et al.   CELL

Probing the Roles of the Two Different Dimers Mediated by the Receiver Domain of the Response Regulator PhoB

(2009) Timothy R. Mack et al.   JOURNAL OF MOLECULAR BIOLOGY

Autoregulation of antibiotic biosynthesis by binding of the end product to an atypical response regulator

(2009) L. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural plasticity and catalysis regulation of a thermosensor histidine kinase

(2009) D. Albanesi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Universally applicable methods for monitoring response regulator aspartate phosphorylation both in vitro and in vivo using Phos-tag-based reagents

(2008) Christopher M. Barbieri et al.   ANALYTICAL BIOCHEMISTRY

Allosteric Regulation of Histidine Kinases by Their Cognate Response Regulator Determines Cell Fate

(2008) Ralf Paul et al.   CELL

Rewiring the Specificity of Two-Component Signal Transduction Systems

(2008) Jeffrey M. Skerker et al.   CELL

Molecular Physiology of Mammalian Glucokinase

(2008) P. B. Iynedjian   CELLULAR AND MOLECULAR LIFE SCIENCES

Phosphorylation-independent activation of the atypical response regulator NblR

(2008) D. Ruiz et al.   MICROBIOLOGY-SGM

Identification of direct residue contacts in protein-protein interaction by message passing

(2008) M. Weigt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA