Colonic Hypersensitivity and Sensitization of Voltage-gated Sodium Channels in Primary Sensory Neurons in Rats with Diabetes

The role of TNF-alpha/NF-kappa B pathway on the up-regulation of voltage-gated sodium channel Nav1.7 in DRG neurons of rats with diabetic neuropathy

(2014) Yangliang Huang et al.   NEUROCHEMISTRY INTERNATIONAL

Neonatal colonic inflammation sensitizes voltage-gated Na+ channels via upregulation of cystathionine β-synthetase expression in rat primary sensory neurons

(2013) Ruobing Qu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Persistent mechanical allodynia positively correlates with an increase in activated microglia and increased P-p38 mitogen-activated protein kinase activation in streptozotocin-induced diabetic rats

(2013) K.-I. Cheng et al.   EUROPEAN JOURNAL OF PAIN

Electroacupuncture Reduces Carrageenan- and CFA-Induced Inflammatory Pain Accompanied by Changing the Expression of Nav1.7 and Nav1.8, rather than Nav1.9, in Mice Dorsal Root Ganglia

(2013) Chun-Ping Huang et al.   Evidence-based Complementary and Alternative Medicine

Promoted Interaction of Nuclear Factor- B with Demethylated Cystathionine- -Synthetase Gene Contributes to Gastric Hypersensitivity in Diabetic Rats

(2013) H.-H. Zhang et al.   JOURNAL OF NEUROSCIENCE

Impact of Myenteric Plexus Alterations on Diabetes Related Gastrointestinal Dysmotility

(2013) Kyung Sik Park   Journal of Neurogastroenterology and Motility

Gastrointestinal Motility Changes and Myenteric Plexus Alterations in Spontaneously Diabetic Biobreeding Rats

(2013) Ingrid Demedts et al.   Journal of Neurogastroenterology and Motility

Neonatal maternal deprivation sensitizes voltage-gated sodium channel currents in colon-specific dorsal root ganglion neurons in rats

(2012) Shufen Hu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Reduced conduction failure of the main axon of polymodal nociceptive C-fibres contributes to painful diabetic neuropathy in rats

(2012) Wei Sun et al.   BRAIN

Gabapentin reduces allodynia and hyperalgesia in painful diabetic neuropathy rats by decreasing expression level of Nav1.7 and p-ERK1/2 in DRG neurons

(2012) Jun-Long Zhang et al.   BRAIN RESEARCH

Electroacupuncture Suppresses Mechanical Allodynia and Nuclear Factor Kappa B Signaling in Streptozotocin-Induced Diabetic Rats

(2012) Lei Shi et al.   CNS Neuroscience & Therapeutics

Upregulation of Cystathionine Beta-Synthetase Expression by Nuclear Factor-Kappa B Activation Contributes to Visceral Hypersensitivity in Adult Rats with Neonatal Maternal Deprivation

(2012) Lin Li et al.   Molecular Pain

In vitro hyperglycemia enhances sodium currents in dorsal root ganglion neurons: An effect attenuated by carbamazepine

(2012) J.N. Singh et al.   NEUROSCIENCE

Upregulation of Cystathionine β-Synthetase Expression Contributes to Visceral Hyperalgesia Induced by Heterotypic Intermittent Stress in Rats

(2012) Yongmeng Wang et al.   PLoS One

Diabetic Visceral Hypersensitivity Is Associated With Activation of Mitogen-Activated Kinase in Rat Dorsal Root Ganglia

(2011) G. Grabauskas et al.   DIABETES

Phenotypic Switching in Diabetic Gastroparesis: Mechanism Directs Therapy

(2011) Chung Owyang   GASTROENTEROLOGY

Mechanisms Underlying Purinergic P2X3 Receptor-Mediated Mechanical Allodynia Induced in Diabetic Rats

(2011) Guang-Yin Xu et al.   Molecular Pain

Targeting voltage-gated sodium channels for treatment for chronic visceral pain

(2011) Fei-Hu Qi   WORLD JOURNAL OF GASTROENTEROLOGY

Gastroesophageal Reflux Disease in Type II Diabetes Mellitus With or Without Peripheral Neuropathy

(2011) Sehe Dong Lee et al.   Journal of Neurogastroenterology and Motility

Effects of a new potent analog of tocainide on hNav1.7 sodium channels and in vivo neuropathic pain models

(2010) C. Ghelardini et al.   NEUROSCIENCE

A Peripherally Acting Nav1.7 Sodium Channel Blocker Reverses Hyperalgesia and Allodynia on Rat Models of Inflammatory and Neuropathic Pain

(2009) Erin McGowan et al.   ANESTHESIA AND ANALGESIA

The Endogenous Hydrogen Sulfide Producing Enzyme Cystathionine-β Synthase Contributes to Visceral Hypersensitivity in a Rat Model of Irritable Bowel Syndrome

(2009) Guang-Yin Xu et al.   Molecular Pain

Increased Peripheral Nerve Excitability and Local Nav1.8 RNA Up-Regulation in Painful Neuropathy

(2009) Devang Kashyap Thakor et al.   Molecular Pain

P2X receptor-mediated visceral hyperalgesia in a rat model of chronic visceral hypersensitivity

(2008) G-Y Xu et al.   GUT

Deficiency of cytomegalovirus (CMV)-specific CD8+ T cells in patients presenting with late-onset CMV disease several years after transplantation

(2008) N.W. Cummins et al.   Transplant Infectious Disease

Sodium channels and nociception: recent concepts and therapeutic opportunities

(2007) D KRAFTE et al.   CURRENT OPINION IN PHARMACOLOGY

Changes in the expression of NaV1.7, NaV1.8 and NaV1.9 in a distinct population of dorsal root ganglia innervating the rat knee joint in a model of chronic inflammatory joint pain

(2007) Iain T. Strickland et al.   EUROPEAN JOURNAL OF PAIN