Sulfonium ions as inhibitors of the mycobacterial galactofuranosyltransferase GlfT2

Naturally Occurring Sulfonium-Ion Glucosidase Inhibitors and Their Derivatives: A Promising Class of Potential Antidiabetic Agents

(2013) Sankar Mohan et al.   ACCOUNTS OF CHEMICAL RESEARCH

Synthesis of Nitrogen-Containing Furanose Sugar Nucleotides for Use as Enzymatic Probes

(2013) Ryan B. Snitynsky et al.   ORGANIC LETTERS

A Processive Carbohydrate Polymerase That Mediates Bifunctional Catalysis Using a Single Active Site

(2012) John F. May et al.   BIOCHEMISTRY

Recent structures, evolution and mechanisms of glycosyltransferases

(2012) Christelle Breton et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Tetrameric Structure of the GlfT2 Galactofuranosyltransferase Reveals a Scaffold for the Assembly of Mycobacterial Arabinogalactan

(2012) Robert W. Wheatley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synthetic UDP-galactofuranose analogs reveal critical enzyme–substrate interactions in GlfT2-catalyzed mycobacterial galactan assembly

(2012) Myles B. Poulin et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Isolation, structure identification and SAR studies on thiosugar sulfonium salts, neosalaprinol and neoponkoranol, as potent α-glucosidase inhibitors

(2011) Weijia Xie et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Probing the Intestinal α-Glucosidase Enzyme Specificities of Starch-Digesting Maltase-Glucoamylase and Sucrase-Isomaltase: Synthesis and Inhibitory Properties of 3′- and 5′-Maltose-Extended De-O-sulfonated Ponkoranol

(2011) Razieh Eskandari et al.   CHEMISTRY-A EUROPEAN JOURNAL

Carbasugar Analogues of Galactofuranosides: Pseudodisaccharide Mimics of Fragments of Mycobacterial Arabino­galactan

(2011) Jens Frigell et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Iminosugars as therapeutic agents: recent advances and promising trends

(2011) Robert J Nash et al.   Future Medicinal Chemistry

Monitoring Processivity and Length Control of a Carbohydrate Polymerase

(2011) Matthew R. Levengood et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Inhibition of Escherichia coli glycosyltransferase MurG and Mycobacterium tuberculosis Gal transferase by uridine-linked transition state mimics

(2010) Amy E. Trunkfield et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis of sugar–amino acid–nucleosides as potential glycosyltransferase inhibitors

(2010) Kannan Vembaiyan et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Towards the elusive structure of kotalanol, a naturally occurring glucosidase inhibitor

(2010) Sankar Mohan et al.   NATURAL PRODUCT REPORTS

Facile synthesis of de-O-sulfated salacinols: Revision of the structure of neosalacinol, a potent α-glucosidase inhibitor

(2009) Genzoh Tanabe et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Chemistry and Biology of Galactofuranose-Containing Polysaccharides

(2009) Michele R. Richards et al.   CHEMBIOCHEM

STD-NMR Studies Suggest that Two Acceptor Substrates for GlfT2, a Bifunctional Galactofuranosyltransferase Required for the Biosynthesis ofMycobacterium tuberculosisArabinogalactan, Compete for the Same Binding Site

(2009) Monica G. Szczepina et al.   CHEMBIOCHEM

Salaprionol and Ponkoranol with Thiosugar Sulfonium Sulfate Structure from Salacia prinoides and a-Glucosidase Inhibitory Activity of Ponkoranol and Kotalanol Desulfate

(2009) Masayuki Yoshikawa et al.   HETEROCYCLES

Structure Proof and Synthesis of Kotalanol and De-O-sulfonated Kotalanol, Glycosidase Inhibitors Isolated from an Herbal Remedy for the Treatment of Type-2 Diabetes

(2009) Kumarasamy Jayakanthan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Development of a coupled spectrophotometric assay for GlfT2, a bifunctional mycobacterial galactofuranosyltransferase

(2008) Natisha L. Rose et al.   CARBOHYDRATE RESEARCH

Synthesis of Galactofuranose-Containing Acceptor Substrates for Mycobacterial Galactofuranosyltransferases

(2008) Gladys C. Completo et al.   JOURNAL OF ORGANIC CHEMISTRY

Glycosyltransferases: Structures, Functions, and Mechanisms

(2007) L.L. Lairson et al.   Annual Review of Biochemistry

Expression, purification and characterisation of soluble GlfT and the identification of a novel galactofuranosyltransferase Rv3782 involved in priming GlfT-mediated galactan polymerisation in Mycobacterium tuberculosis

(2007) Luke J. Alderwick et al.   PROTEIN EXPRESSION AND PURIFICATION