Preparation and evaluation of BBB-permeable trehalose derivatives as potential therapeutic agents for Huntington's disease

A Blood-brain Barrier Permeable Derivative of 5-Fluorouracil: Preparation, Intracellular Localization, and Mouse Tissue Distribution

(2011) Jung-Kyun Im et al.   BULLETIN OF THE KOREAN CHEMICAL SOCIETY

Preparation of blood-brain barrier-permeable paclitaxel-carrier conjugate and its chemotherapeutic activity in the mouse glioblastoma model

(2011) Juyoun Jin et al.   MedChemComm

Chemical Inducers of Autophagy That Enhance the Clearance of Mutant Proteins in Neurodegenerative Diseases

(2010) Maurizio Renna et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mouse models of Huntington's disease and methodological considerations for therapeutic trials

(2009) Robert J. Ferrante   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Small molecule drug discovery for Huntington's Disease

(2009) Wolfgang Fecke et al.   DRUG DISCOVERY TODAY

Novel lipidated sorbitol-based molecular transporters for non-viral gene delivery

(2009) Tomoko Higashi et al.   JOURNAL OF CONTROLLED RELEASE

The pathogenic mechanisms of polyglutamine diseases and current therapeutic strategies

(2009) Peter O. Bauer et al.   JOURNAL OF NEUROCHEMISTRY

Cytoplasmic Inclusions of Htt Exon1 Containing an Expanded Polyglutamine Tract Suppress Execution of Apoptosis in Sympathetic Neurons

(2009) M. A. King et al.   JOURNAL OF NEUROSCIENCE

The encapsulation and intracellular delivery of trehalose using a thermally responsive nanocapsule

(2009) Wujie Zhang et al.   NANOTECHNOLOGY

Trehalose impairs aggregation of PrPSc molecules and protects prion-infected cells against oxidative damage

(2008) Florence Béranger et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Novel targets for Huntington's disease in an mTOR-independent autophagy pathway

(2008) Andrea Williams et al.   Nature Chemical Biology

Recent advances in cell-penetrating, non-peptide molecular carriers

(2007) Sung-Kee Chung et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS