Antithrombin stabilisation by sulfated carbohydrates correlates with anticoagulant activity

A zinc complex of heparan sulfate destabilises lysozyme and alters its conformation

(2012) Ashley J. Hughes et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

An unusual antithrombin-binding heparin octasaccharide with an additional 3-O-sulfated glucosamine in the active pentasaccharide sequence

(2012) Marco Guerrini et al.   BIOCHEMICAL JOURNAL

Exploring the Molecular Linkage of Protein Stability Traits for Enzyme Optimization by Iterative Truncation and Evolution

(2012) Janina Speck et al.   BIOCHEMISTRY

Circular dichroism beamline B23 at the Diamond Light Source

(2011) Rohanah Hussain et al.   JOURNAL OF SYNCHROTRON RADIATION

Differential Scanning Fluorimetry Measurement of Protein Stability Changes upon Binding to Glycosaminoglycans: A Screening Test for Binding Specificity

(2010) Katarzyna A. Uniewicz et al.   ANALYTICAL CHEMISTRY

A heparin mimetic isolated from a marine shrimp suppresses neovascularization

(2010) J. L. DREYFUSS et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Comparable stabilisation, structural changes and activities can be induced in FGF by a variety of HS and non-GAG analogues: implications for sequence-activity relationships

(2010) Timothy R. Rudd et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Interaction of Antithrombin with Sulfated, Low Molecular Weight Lignins

(2009) Brian L. Henry et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Signature 3-O-Sulfo Group of the Anticoagulant Heparin Sequence Is Critical for Heparin Binding to Antithrombin but Is Not Required for Allosteric Activation

(2009) Benjamin Richard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antithrombin-binding Octasaccharides and Role of Extensions of the Active Pentasaccharide Sequence in the Specificity and Strength of Interaction

(2008) Marco Guerrini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY