4.1 Article

Transdermal delivery of insulin using a solid-in-oil nanodispersion enhanced by arginine-rich peptides

Journal

MEDCHEMCOMM
Volume 3, Issue 12, Pages 1496-1499

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2md20059g

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Funding

  1. Ministry of Education, Culture, Sports, Science, and Technology of Japan [24226019]
  2. Japan Society for the Promotion of Science (JSPS) for Young Scientists

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A solid-in-oil nanodispersion that utilizes an oil-based vehicle of proteins was developed as a unique protein-delivery system into the skin. We enhanced the permeability of insulin and accomplished transdermal delivery of insulin by the collaborative effects of a S/O nanodispersion and arginine-rich peptides.

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