An anion structure-activity relationship of imidazolium-based synthetic transporters

We have developed imidazolium-based salts as a new recognition motif with strong anionophoric properties across phospholipid bilayers. We present here factors intrinsic to the imidazolium salts that allow the modulation of their ionophoric properties. We also report the kinetic and thermodynamic parameters of the most active imidazolium salt.