Recent advances in LC–MS/MS analysis of Δ9-tetrahydrocannabinol and its metabolites in biological matrices

Qualitative Confirmation of 9 Synthetic Cannabinoids and 20 Metabolites in Human Urine Using LC–MS/MS and Library Search

(2013) Ariane Wohlfarth et al.   ANALYTICAL CHEMISTRY

Comparison of LUCIO®-direct ELISA with CEDIA immunoassay for ‘zero tolerance’ drug screening in urine as required by the German re-licensing guidelines

(2013) Ronald Agius et al.   Drug Testing and Analysis

Automated Solid-Phase Extraction-Liquid Chromatography-Tandem Mass Spectrometry Analysis of 11-nor- 9-Tetrahydrocannabinol-9-Carboxylic Acid in Human Urine Specimens: Application to a High-Throughput Urine Analysis Laboratory

(2013) P. V. Robandt et al.   JOURNAL OF ANALYTICAL TOXICOLOGY

Disposition of Cannabichromene, Cannabidiol, and  9-Tetrahydrocannabinol and its Metabolites in Mouse Brain following Marijuana Inhalation Determined by High-Performance Liquid Chromatography-Tandem Mass Spectrometry

(2013) J. L. Poklis et al.   JOURNAL OF ANALYTICAL TOXICOLOGY

Development and validation of an LC-MS/MS method for quantification of Δ9-tetrahydrocannabinolic acid A (THCA-A), THC, CBN and CBD in hair

(2013) Nadine Roth et al.   JOURNAL OF MASS SPECTROMETRY

Sensitive determination of prohibited drugs in dried blood spots (DBS) for doping controls by means of a benchtop quadrupole/Orbitrap mass spectrometer

(2012) Andreas Thomas et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Simultaneous and sensitive LC–MS/MS determination of tetrahydrocannabinol and metabolites in human plasma

(2012) N. Ferreirós et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Ultra-Sensitive Measurements of 11-Nor-Δ9-Tetrahydrocannabinol-9-Carboxylic Acid in Oral Fluid by Microflow Liquid Chromatography–Tandem Mass Spectrometry Using a Benchtop Quadrupole/Orbitrap Mass Spectrometer

(2012) Xiang He et al.   ANALYTICAL CHEMISTRY

Analysis of 11-nor-Δ9-tetrahydrocannabinol-9-carboxylic acid and its glucuronide in urine by capillary electrophoresis/mass spectrometry

(2012) Yoshiaki Iwamuro et al.   BIOMEDICAL CHROMATOGRAPHY

Simultaneous quantification of free and glucuronidated cannabinoids in human urine by liquid chromatography tandem mass spectrometry

(2012) Karl B. Scheidweiler et al.   CLINICA CHIMICA ACTA

Prescription and illicit psychoactive drugs in oral fluid—LC–MS/MS method development and analysis of samples from Brazilian drivers

(2012) Ivomar Zancanaro et al.   FORENSIC SCIENCE INTERNATIONAL

Segmental Hair Analysis for 11-Nor- 9-Tetrahydrocannabinol-9-Carboxylic Acid and the Patterns of Cannabis Use

(2012) E. Han et al.   JOURNAL OF ANALYTICAL TOXICOLOGY

Analysis of Tetrahydrocannabinol and its Metabolite, 11-Nor- 9-Tetrahydrocannabinol-9-Carboxylic Acid, in Oral Fluid using Liquid Chromatography with Tandem Mass Spectrometry

(2012) C. Coulter et al.   JOURNAL OF ANALYTICAL TOXICOLOGY

Determination of 22 synthetic cannabinoids in human hair by liquid chromatography–tandem mass spectrometry

(2012) Melanie Hutter et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

LC–MS/MS method for the quantitation of metabolites of eight commonly-used synthetic cannabinoids in human urine – An Australian perspective

(2012) Andrew D. de Jager et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

High-throughput bioanalytical method for analysis of synthetic cannabinoid metabolites in urine using salting-out sample preparation and LC–MS/MS

(2012) Enrique G. Yanes et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Simultaneous determination in hair of multiclass drugs of abuse (including THC) by ultra-high performance liquid chromatography–tandem mass spectrometry

(2012) D. Di Corcia et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Fast liquid chromatography/tandem mass spectrometry determination of cannabinoids in micro volume blood samples after dabsyl derivatization

(2012) C. Lacroix et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Evolution of the Content of THC and Other Major Cannabinoids in Drug-Type Cannabis Cuttings and Seedlings During Growth of Plants*

(2012) Benjamin De Backer et al.   JOURNAL OF FORENSIC SCIENCES

LC-MS/MS analysis of Δ9-tetrahydrocannabinolic acid A in serum after protein precipitation using an in-house synthesized deuterated internal standard

(2012) Ariane Wohlfarth et al.   JOURNAL OF MASS SPECTROMETRY

Rapid and robust confirmation and quantification of 11-nor-Δ9-tetrahydrocannabinol-9-carboxylic acid (THC-COOH) in urine by column switching LC-MS-MS analysis

(2012) Gabriele Zanchetti et al.   JOURNAL OF MASS SPECTROMETRY

Identification of the major urinary metabolites in man of seven synthetic cannabinoids of the aminoalkylindole type present as adulterants in ‘herbal mixtures’ using LC-MS/MS techniques

(2012) M. Hutter et al.   JOURNAL OF MASS SPECTROMETRY

Simultaneous analysis of several synthetic cannabinoids, THC, CBD and CBN, in hair by ultra-high performance liquid chromatography tandem mass spectrometry. Method validation and application to real samples

(2012) A. Salomone et al.   JOURNAL OF MASS SPECTROMETRY

Monitoring of chronic Cannabis abuse: An LC–MS/MS method for hair analysis

(2012) Laura Mercolini et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

High-throughput liquid chromatography/mass spectrometry method for the quantitation of small molecules using accurate mass technologies in supporting discovery drug screening

(2012) Xiao Ding et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Enzymatic Digestion and Selective Quantification of Underivatised Delta-9-Tetrahydrocannabinol and Cocaine in Human Hair Using Gas Chromatography-Mass Spectrometry

(2012) Salah Eddine Breidi et al.   Journal of Analytical Methods in Chemistry

Direct quantification of cannabinoids and cannabinoid glucuronides in whole blood by liquid chromatography–tandem mass spectrometry

(2011) David M. Schwope et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

On-line SPE LC-MS/MS for the quantification of Δ9-tetrahydrocannabinol (THC) and its two major metabolites in human peripheral blood by liquid chromatography tandem mass spectrometry

(2011) Stefan König et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Identification of Recent Cannabis Use: Whole-Blood and Plasma Free and Glucuronidated Cannabinoid Pharmacokinetics following Controlled Smoked Cannabis Administration

(2011) D. M. Schwope et al.   CLINICAL CHEMISTRY

A preliminary investigation on the distribution of cannabinoids in man

(2011) Antonia Gronewold et al.   FORENSIC SCIENCE INTERNATIONAL

Detection and quantification of 11-nor-Δ9-tetrahydrocannabinol-9-carboxylic acid in hair by GC/MS/MS in Negative Chemical Ionization mode (NCI) with a simple and rapid liquid/liquid extraction

(2011) M. Minoli et al.   FORENSIC SCIENCE INTERNATIONAL

A rapid and sensitive method for the identification of delta-9-tetrahydrocannabinol in oral fluid by liquid chromatography–tandem mass spectrometry

(2011) Anna Molnar et al.   FORENSIC SCIENCE INTERNATIONAL

Target screening and confirmation of 35 licit and illicit drugs and metabolites in hair by LC–MSMS

(2011) Elena Lendoiro et al.   FORENSIC SCIENCE INTERNATIONAL

Detection of  9-Tetrahydrocannabinol in Exhaled Breath Collected from Cannabis Users

(2011) O. Beck et al.   JOURNAL OF ANALYTICAL TOXICOLOGY

Cannabinoids in Postmortem Toxicology

(2011) N. P. Lemos et al.   JOURNAL OF ANALYTICAL TOXICOLOGY

Online extraction LC–MS/MS method for the simultaneous quantitative confirmation of urine drugs of abuse and metabolites: Amphetamines, opiates, cocaine, cannabis, benzodiazepines and methadone

(2011) Andrew D. de Jager et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Surface-activated chemical ionization combined with electrospray ionization and mass spectrometry for the analysis of cannabinoids in biological samples. Part I: Analysis of 11-nor-9-carboxytetrahydro-cannabinol

(2011) Matteo Conti et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

A fast method for screening and/or quantitation of tetrahydrocannabinol and metabolites in urine by automated SPE/LC/MS/MS

(2010) Eshwar Jagerdeo et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Broad-spectrum drug screening of meconium by liquid chromatography with tandem mass spectrometry and time-of-flight mass spectrometry

(2010) Johanna Ristimaa et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Detection and identification of 700 drugs by multi-target screening with a 3200 Q TRAP® LC-MS/MS system and library searching

(2010) S. Dresen et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Pitfalls Associated with the Use of Liquid Chromatography-Tandem Mass Spectrometry in the Clinical Laboratory

(2010) M. Vogeser et al.   CLINICAL CHEMISTRY

Temporal indication of cannabis use by means of THC glucuronide determination

(2010) Ute Mareck et al.   Drug Testing and Analysis

LC–MS–MS method for simultaneous determination of THCCOOH and THCCOOH-glucuronide in urine: Application to workplace confirmation tests

(2010) M. Felli et al.   FORENSIC SCIENCE INTERNATIONAL

Monitoring of herbal mixtures potentially containing synthetic cannabinoids as psychoactive compounds

(2010) Sebastian Dresen et al.   JOURNAL OF MASS SPECTROMETRY

International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid Receptors and Their Ligands: Beyond CB1 and CB2

(2010) R. G. Pertwee et al.   PHARMACOLOGICAL REVIEWS

A review of current trends and advances in modern bio-analytical methods: Chromatography and sample preparation

(2009) Lucie Nováková et al.   ANALYTICA CHIMICA ACTA

Simultaneous Screening and Quantification of 29 Drugs of Abuse in Oral Fluid by Solid-Phase Extraction and Ultraperformance LC-MS/MS

(2009) N. Badawi et al.   CLINICAL CHEMISTRY

Quantitation of tetrahydrocannabinol in hair using immunoassay and liquid chromatography with tandem mass spectrometric detection

(2009) Cynthia Coulter et al.   Drug Testing and Analysis

‘Spice’ and other herbal blends: harmless incense or cannabinoid designer drugs?

(2009) Volker Auwärter et al.   JOURNAL OF MASS SPECTROMETRY

A semi-automated solid-phase extraction liquid chromatography/tandem mass spectrometry method for the analysis of tetrahydrocannabinol and metabolites in whole blood

(2009) Eshwar Jagerdeo et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Multiclass analysis of illicit drugs in plasma and oral fluids by LC-MS/MS

(2008) M. Sergi et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Determination of illicit and medicinal drugs and their metabolites in oral fluid and preserved oral fluid by liquid chromatography–tandem mass spectrometry

(2008) Marta Concheiro et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Simultaneous analysis of THC and its metabolites in blood using liquid chromatography–tandem mass spectrometry

(2008) M DELMARRAMIREZFERNANDEZ et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Determination of plasma and urine levels of Δ9-tetrahydrocannabinol and its main metabolite by liquid chromatography after solid-phase extraction

(2007) Laura Mercolini et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Cannabinoid pharmacology: the first 66 years

(2006) Roger G Pertwee   BRITISH JOURNAL OF PHARMACOLOGY