Flow cytometry: a flexible tool for biomarker research

Early immunologic correlates of HIV protection can be identified from computational analysis of complex multivariate T-cell flow cytometry assays*

(2012) Nima Aghaeepour et al.   BIOINFORMATICS

Phosphospecific flow cytometry for pharmacodynamic drug monitoring: Analysis of the JAK-STAT signaling pathway

(2012) Ramin Vafadari et al.   CLINICA CHIMICA ACTA

Phospho-specific Flow: Fixating on the Target

(2012) M. Levis   CLINICAL CANCER RESEARCH

A simple multicolor flow cytometry protocol for detection and molecular characterization of circulating tumor cells in epithelial cancers

(2012) Tsvetana Hristozova et al.   CYTOMETRY PART A

Cytometry by Time-of-Flight Shows Combinatorial Cytokine Expression and Virus-Specific Cell Niches within a Continuum of CD8+ T Cell Phenotypes

(2012) Evan W. Newell et al.   IMMUNITY

Translational Applications of Flow Cytometry in Clinical Practice

(2012) D. L. Jaye et al.   JOURNAL OF IMMUNOLOGY

EuroFlow antibody panels for standardized n-dimensional flow cytometric immunophenotyping of normal, reactive and malignant leukocytes

(2012) J J M van Dongen et al.   LEUKEMIA

Biomarkers: hopes and challenges in the path from discovery to clinical practice

(2012) Nikolaos G. Frangogiannis   Translational Research

A deep profiler's guide to cytometry

(2012) Sean C. Bendall et al.   TRENDS IN IMMUNOLOGY

Blood memory B cells are disturbed and predict the response to rituximab in patients with rheumatoid arthritis

(2011) Jérémie Sellam et al.   ARTHRITIS AND RHEUMATISM

Flow cytometry in the post fluorescence era

(2011) Garry P. Nolan   BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY

Challenges of drug discovery in novel target space. The discovery and evaluation of PF-3893787: A novel histamine H4 receptor antagonist

(2011) Charles E. Mowbray et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

SB-656933, a novel CXCR2 selective antagonist, inhibits ex vivo neutrophil activation and ozone-induced airway inflammation in humans

(2011) Aili L. Lazaar et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Assay validation of phosphorylated S6 ribosomal protein for a pharmacodynamic monitoring of mTOR-inhibitors in peripheral human blood

(2011) Maja-Theresa Dieterlen et al.   CYTOMETRY PART B-CLINICAL CYTOMETRY

Evaluation of a flow cytometry method for CD4 T cell enumeration based on volumetric primary CD4 gating using thermoresistant reagents

(2011) Tandakha Ndiaye Dieye et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Characterization of a Human Cervical CD4+ T Cell Subset Coexpressing Multiple Markers of HIV Susceptibility

(2011) L. R. McKinnon et al.   JOURNAL OF IMMUNOLOGY

Polychromatic flow cytometry in the clinical laboratory

(2011) William A. Sewell et al.   PATHOLOGY

Single-Cell Mass Cytometry of Differential Immune and Drug Responses Across a Human Hematopoietic Continuum

(2011) S. C. Bendall et al.   SCIENCE

Role of Flow Cytometry of Peripheral Blood and Bone Marrow Aspirates in Early Myeloma

(2011) Constance M. Yuan et al.   SEMINARS IN HEMATOLOGY

Natural killer cell subsets in man and rodents

(2011) M. Inngjerdingen et al.   TISSUE ANTIGENS

Determination of Absolute Counts of Circulating Regulatory T Cells in Cynomolgus Macaques Using an Optimized Flow Cytometric Method

(2011) Stacie M. Clark et al.   TOXICOLOGIC PATHOLOGY

Assessment of Immunological Markers as Mediators of Graft Vasculopathy Development in Heart Transplantation

(2011) S. Mirabet et al.   TRANSPLANTATION PROCEEDINGS

Conference Report: Analytical challenges in the qualification and validation of pharmacodynamic biomarkers

(2011) Richard Houghton et al.   Bioanalysis

Single Tube, Six-Color Flow Cytometric Analysis Is a Sensitive and Cost-Effective Technique for Assaying Clonal Plasma Cells

(2010) Derek K. Marsee et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Single-cell network profiling (SCNP) by flow cytometry in autoimmune disease

(2010) Todd M. Covey et al.   AUTOIMMUNITY

Monoclonal antibody TGN1412 trial failure explained by species differences in CD28 expression on CD4+ effector memory T-cells

(2010) D Eastwood et al.   BRITISH JOURNAL OF PHARMACOLOGY

Biomarkers of immunoregulatory status in stable liver transplant recipients undergoing weaning of immunosuppressive therapy

(2010) Olga Millán et al.   CLINICAL IMMUNOLOGY

Immunophenotyping of lymphocyte, monocyte and dendritic cell subsets in normal rhesus macaques by 12-color flow cytometry: Clarification on DC heterogeneity

(2010) Patrick Autissier et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Flow cytometry-based biomarkers in translational medicine and drug development

(2010) Virginia Litwin et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Naïve and memory B cells in the rhesus macaque can be differentiated by surface expression of CD27 and have differential responses to CD40 ligation

(2010) David Kuhrt et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Flow cytometric methods for prenatal and neonatal diagnosis

(2010) Michèle G. Curtis et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Analysis of B cell subsets following pancreatic islet cell transplantation in a patient with type 1 diabetes by cytometric fingerprinting

(2010) Debora R. Sekiguchi et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Validation of a flow cytometry based G2M delay cell cycle assay for use in evaluating the pharmacodynamic response to Aurora A inhibition

(2010) Jose Estevam et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Recommendations for the validation of flow cytometric testing during drug development: II assays

(2010) Denise M. O'Hara et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Flow cytometry of intestinal intraepithelial lymphocytes in celiac disease

(2010) Francisco Leon   JOURNAL OF IMMUNOLOGICAL METHODS

Targeting early infection to prevent HIV-1 mucosal transmission

(2010) Ashley T. Haase   NATURE

Modulation of Cell Signaling Networks after CTLA4 Blockade in Patients with Metastatic Melanoma

(2010) Begoña Comin-Anduix et al.   PLoS One

FOXP3 Expression Is Upregulated in CD4+T Cells in Progressive HIV-1 Infection and Is a Marker of Disease Severity

(2010) Melinda S. Suchard et al.   PLoS One

Development and validation of flow cytometry methods for pharmacodynamic clinical biomarkers

(2010) Dianna Y Wu et al.   Bioanalysis

Flow Cytometric Immunophenotyping and Minimal Residual Disease Analysis in Multiple Myeloma

(2009) Ritu Gupta et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Interleukin-2 in CD8+ T cells correlates with Banff score during organ rejection in liver transplant recipients

(2009) Bora Akoglu et al.   CLINICAL AND EXPERIMENTAL MEDICINE

From research tool to routine test: CD38 monitoring in HIV patients

(2009) Lindi M. Coetzee et al.   CYTOMETRY PART B-CLINICAL CYTOMETRY

From biomarker strategies to biomarker activities and back

(2009) Alain J. van Gool et al.   DRUG DISCOVERY TODAY

High Throughput, Parallel Imaging and Biomarker Quantification of Human Spermatozoa by ImageStream Flow Cytometry

(2009) Clayton Buckman et al.   Systems Biology in Reproductive Medicine

Flow cytometric immunophenotyping for hematologic neoplasms

(2008) F. E. Craig et al.   BLOOD

Multiparameter flow cytometric remission is the most relevant prognostic factor for multiple myeloma patients who undergo autologous stem cell transplantation

(2008) B. Paiva et al.   BLOOD

CD8/CD38 activation yields important clinical information of effective antiretroviral therapy: Findings from the first year of the CIPRA-SA cohort

(2008) Deborah K. Glencross et al.   CYTOMETRY PART B-CLINICAL CYTOMETRY

Close association of CD8+/CD38brightwith HIV-1 replication and complex relationship with CD4+T-cell count

(2008) Edouard Tuaillon et al.   CYTOMETRY PART B-CLINICAL CYTOMETRY

Report of the European Myeloma Network on multiparametric flow cytometry in multiple myeloma and related disorders

(2008) A. C. Rawstron et al.   HAEMATOLOGICA

A chromatic explosion: the development and future of multiparameter flow cytometry

(2008) Pratip K. Chattopadhyay et al.   IMMUNOLOGY

Validation of a flow cytometry based chemokine internalization assay for use in evaluating the pharmacodynamic response to a receptor antagonist

(2008) Timothy Wyant et al.   Journal of Translational Medicine

Neutrophil Adhesion and Activation under Flow

(2008) Alexander Zarbock et al.   MICROCIRCULATION

Translational Medicine for Stroke Drug Discovery: The Pharmaceutical Industry Perspective

(2008) G. Z. Feuerstein et al.   STROKE