LC–MS/MS bioanalytical challenge: ultra-high sensitivity assays

Novel strategies for microdose studies using non-radiolabeled compounds

(2011) Kazuya Maeda et al.   ADVANCED DRUG DELIVERY REVIEWS

A rugged and accurate liquid chromatography–tandem mass spectrometry method for quantitative determination of BMS-790052 in plasma

(2011) Hao Jiang et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Targeted LC–MS derivatization for aldehydes and carboxylic acids with a new derivatization agent 4-APEBA

(2010) Mark Eggink et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Improved Sensitivity Mass Spectrometric Detection of Eicosanoids by Charge Reversal Derivatization

(2010) James G. Bollinger et al.   ANALYTICAL CHEMISTRY

A low flow ionization technique to integrate quantitative and qualitative small molecule bioanalysis

(2010) Ragu Ramanathan et al.   INTERNATIONAL JOURNAL OF MASS SPECTROMETRY

Quantitative determination of BAF312, a S1P-R modulator, in human urine by LC–MS/MS: Prevention and recovery of lost analyte due to container surface adsorption

(2010) Wenkui Li et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Development and validation of sensitive and selective LC–MS/MS methods for the determination of BMS-708163, a γ-secretase inhibitor, in plasma and cerebrospinal fluid using deprotonated or formate adduct ions as precursor ions

(2010) Huidong Gu et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Simple and practical derivatization procedure for enhanced detection of carboxylic acids in liquid chromatography–electrospray ionization-tandem mass spectrometry

(2010) Tatsuya Higashi et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Recent advances in application of hydrophilic interaction chromatography for quantitative bioanalysis

(2010) Wenying Jian et al.   JOURNAL OF SEPARATION SCIENCE

Effect of mobile phase pH, aqueous-organic ratio, and buffer concentration on electrospray ionization tandem mass spectrometric fragmentation patterns: implications in liquid chromatography/tandem mass spectrometric bioanalysis

(2010) Jian Wang et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Liquid chromatography/tandem mass spectrometry sensitivity enhancement via online sample dilution and trapping: applications in microdosing and dried blood spot (DBS) bioanalysis

(2010) Fumin Li et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Analysis of estrogens in serum and plasma from postmenopausal women: Past present, and future

(2010) Ian A. Blair   STEROIDS

Utilization of DBS within drug discovery: development of a serial microsampling pharmacokinetic study in mice

(2010) Graeme T Clark et al.   Bioanalysis

Early human ADME using microdoses and microtracers: bioanalytical considerations

(2010) Stephen R Dueker et al.   Bioanalysis

Microfluidic LC–MS for analysis of small-volume biofluid samples: where we have been and where we need to go

(2010) Paul Rainville   Bioanalysis

Molecularly imprinted polymers for solid-phase extraction of 1-methyladenosine from human urine

(2009) Sonia Scorrano et al.   ANALYTICA CHIMICA ACTA

Recent developments and applications of microextraction techniques in drug analysis

(2009) Hiroyuki Kataoka   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Systematic LC-MS/MS bioanalytical method development that incorporates plasma phospholipids risk avoidance, usage of incurred sample and well thought-out chromatography

(2009) Mohammed Jemal et al.   BIOMEDICAL CHROMATOGRAPHY

Microdosing, Imaging Biomarkers and SPECT: A Multi-Sided Tripod to Accelerate Drug Development

(2009) Ernest Pauwels et al.   CURRENT PHARMACEUTICAL DESIGN

Sensitive and cost-effective LC–MS/MS method for quantitation of CVT-6883 in human urine using sodium dodecylbenzenesulfonate additive to eliminate adsorptive losses

(2009) Chungwen Chen et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Development and validation of a semi-automated assay for the highly sensitive quantification of Biolimus A9 in human whole blood using high-performance liquid chromatography–tandem mass spectrometry

(2009) Claudia Clavijo et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Validation of bioanalytical LC–MS/MS assays: Evaluation of matrix effects

(2009) Ann Van Eeckhaut et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

A sensitive method for the determination of entecavir at picogram per milliliter level in human plasma by solid phase extraction and high-pH LC–MS/MS

(2009) Duxi Zhang et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Molecularly imprinted polymers as affinity-based separation media for sample preparation

(2009) Jun Haginaka   JOURNAL OF SEPARATION SCIENCE

Importance of using highly pure internal standards for successful liquid chromatography/tandem mass spectrometric bioanalytical assays

(2009) Annik Bergeron et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Quantitative determination of fenoterol and fenoterol derivatives in rat plasma using on-line immunoextraction and liquid chromatography/mass spectrometry

(2008) Hee Seung Kim et al.   JOURNAL OF CHROMATOGRAPHY A