Cortical Reshaping and Functional Recovery Induced by Silk Fibroin Hydrogels-Encapsulated Stem Cells Implanted in Stroke Animals

Dual-function injectable angiogenic biomaterial for the repair of brain tissue following stroke

(2018) Lina R. Nih et al.   NATURE MATERIALS

Hydrogels-Assisted Cell Engraftment for Repairing the Stroke-Damaged Brain: Chimera or Reality

(2018) Daniel González-Nieto et al.   Polymers

Neural stem cell transplantation in ischemic stroke: A role for preconditioning and cellular engineering

(2017) Joshua D Bernstock et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The Role of Endogenous Neurogenesis in Functional Recovery and Motor Map Reorganization Induced by Rehabilitative Therapy after Stroke in Rats

(2017) Takashi Shiromoto et al.   Journal of Stroke & Cerebrovascular Diseases

Safety and efficacy of multipotent adult progenitor cells in acute ischaemic stroke (MASTERS): a randomised, double-blind, placebo-controlled, phase 2 trial

(2017) David C Hess et al.   LANCET NEUROLOGY

The Role of Endogenous Neurogenesis in Functional Recovery and Motor Map Reorganization Induced by Rehabilitative Therapy after Stroke in Rats

(2017) Takashi Shiromoto et al.   Journal of Stroke & Cerebrovascular Diseases

Safety and tolerability of silk fibroin hydrogels implanted into the mouse brain

(2016) Laura Fernández-García et al.   Acta Biomaterialia

Systematic optimization of an engineered hydrogel allows for selective control of human neural stem cell survival and differentiation after transplantation in the stroke brain

(2016) Pouria Moshayedi et al.   BIOMATERIALS

Hydrogels for brain repair after stroke: an emerging treatment option

(2016) Lina Ratiba Nih et al.   CURRENT OPINION IN BIOTECHNOLOGY

TGF-β1 modulates microglial phenotype and promotes recovery after intracerebral hemorrhage

(2016) Roslyn A. Taylor et al.   JOURNAL OF CLINICAL INVESTIGATION

TGF-beta1 regulates human brain pericyte inflammatory processes involved in neurovasculature function

(2016) Justin Rustenhoven et al.   Journal of Neuroinflammation

Stem Cell-Based Therapies for Ischemic Stroke: Preclinical Results and the Potential of Imaging-Assisted Evaluation of Donor Cell Fate and Mechanisms of Brain Regeneration

(2016) Pascal Gervois et al.   MEDICINAL RESEARCH REVIEWS

Preliminary Reports of Stereotaxic Stem Cell Transplants in Chronic Stroke Patients

(2016) Cesar V Borlongan   MOLECULAR THERAPY

3K3A–activated protein C stimulates postischemic neuronal repair by human neural stem cells in mice

(2016) Yaoming Wang et al.   NATURE MEDICINE

Clinical Outcomes of Transplanted Modified Bone Marrow–Derived Mesenchymal Stem Cells in Stroke

(2016) Gary K. Steinberg et al.   STROKE

Reducing GABAA-mediated inhibition improves forelimb motor function after focal cortical stroke in mice

(2016) Claudia Alia et al.   Scientific Reports

Effects of mesenchymal stem cell therapy, in association with pharmacologically active microcarriers releasing VEGF, in an ischaemic stroke model in the rat

(2015) Marie-Sophie Quittet et al.   Acta Biomaterialia

Stem Cell Therapies in Clinical Trials: Progress and Challenges

(2015) Alan Trounson et al.   Cell Stem Cell

Current developments in cell- and biomaterial-based approaches for stroke repair

(2015) Pavla Jendelová et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Long-term dynamics of somatosensory activity in a stroke model of distal middle cerebral artery oclussion

(2015) Juan A Barios et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Distinct Functional Modules for Discrete and Rhythmic Forelimb Movements in the Mouse Motor Cortex

(2015) R. Hira et al.   JOURNAL OF NEUROSCIENCE

Experience with the "Good" Limb Induces Aberrant Synaptic Plasticity in the Perilesion Cortex after Stroke

(2015) S. Y. Kim et al.   JOURNAL OF NEUROSCIENCE

GDF10 is a signal for axonal sprouting and functional recovery after stroke

(2015) Songlin Li et al.   NATURE NEUROSCIENCE

Novel Stroke Therapeutics: Unraveling Stroke Pathophysiology and Its Impact on Clinical Treatments

(2015) Paul M. George et al.   NEURON

Moving Stem Cells to the Clinic: Potential and Limitations for Brain Repair

(2015) Julius A. Steinbeck et al.   NEURON

Stent-Retriever Thrombectomy after Intravenous t-PA vs. t-PA Alone in Stroke

(2015) Jeffrey L. Saver et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Hyaluronan-Based Injectable Hydrogel Improves the Survival and Integration of Stem Cell Progeny following Transplantation

(2015) Brian G. Ballios et al.   Stem Cell Reports

Comparison of administration routes for adipose-derived stem cells in the treatment of middle cerebral artery occlusion in rats

(2014) Guojia Du et al.   ACTA HISTOCHEMICA

Intra-Arterial Delivery of Human Bone Marrow Mesenchymal Stem Cells is a Safe and Effective Way to Treat Cerebral Ischemia in Rats

(2014) Shiwei Du et al.   CELL TRANSPLANTATION

Intracerebral Implantation of Autologous Peripheral Blood Stem Cells in Stroke Patients: A Randomized Phase II Study

(2014) Der-Cherng Chen et al.   CELL TRANSPLANTATION

Optogenetic Mapping after Stroke Reveals Network-Wide Scaling of Functional Connections and Heterogeneous Recovery of the Peri-Infarct

(2014) Diana H. Lim et al.   JOURNAL OF NEUROSCIENCE

Mesoscale Transcranial Spontaneous Activity Mapping in GCaMP3 Transgenic Mice Reveals Extensive Reciprocal Connections between Areas of Somatomotor Cortex

(2014) M. P. Vanni et al.   JOURNAL OF NEUROSCIENCE

Meta-analysis of preclinical studies of mesenchymal stromal cells for ischemic stroke

(2014) Q. Vu et al.   NEUROLOGY

Intravenous Autologous Bone Marrow Mononuclear Stem Cell Therapy for Ischemic Stroke

(2014) Kameshwar Prasad et al.   STROKE

Neural precursor cells in the ischemic brain – integration, cellular crosstalk, and consequences for stroke recovery

(2014) Dirk M. Hermann et al.   Frontiers in Cellular Neuroscience

Hyaluronan, a Crucial Regulator of Inflammation

(2014) Aaron C. Petrey et al.   Frontiers in Immunology

Effects of silk fibroin fiber incorporation on mechanical properties, endothelial cell colonization and vascularization of PDLLA scaffolds

(2013) Matteo Stoppato et al.   BIOMATERIALS

Transplantation of human mesenchymal stem cells loaded on collagen scaffolds for the treatment of traumatic brain injury in rats

(2013) Jian Guan et al.   BIOMATERIALS

Spatiotemporal Dynamics of Functional Clusters of Neurons in the Mouse Motor Cortex during a Voluntary Movement

(2013) R. Hira et al.   JOURNAL OF NEUROSCIENCE

Displacement of Sensory Maps and Disorganization of Motor Cortex After Targeted Stroke in Mice

(2013) T. C. Harrison et al.   STROKE

In vivo optogenetic tracing of functional corticocortical connections between motor forelimb areas

(2013) Riichiro Hira et al.   Frontiers in Neural Circuits

Mesenchymal stem cells restore cortical rewiring after neonatal ischemia in mice

(2012) Cindy T. J. van Velthoven et al.   ANNALS OF NEUROLOGY

Immune Effects of Mesenchymal Stromal Cells in Experimental Stroke

(2012) Franziska Scheibe et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Functional Expansion of Sensorimotor Representation and Structural Reorganization of Callosal Connections in Lower Limb Amputees

(2012) E. L. Simoes et al.   JOURNAL OF NEUROSCIENCE

Therapeutic Effects of hMAPC and hMSC Transplantation after Stroke in Mice

(2012) Silvia Mora-Lee et al.   PLoS One

A role for ephrin-A5 in axonal sprouting, recovery, and activity-dependent plasticity after stroke

(2012) J. J. Overman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human neural stem cells enhance structural plasticity and axonal transport in the ischaemic brain

(2011) Robert H. Andres et al.   BRAIN

Therapeutic time window and dose response of autologous bone marrow mononuclear cells for ischemic stroke

(2011) Bing Yang et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Stroke Treatment Academic Industry Roundtable (STAIR) Recommendations for Maximizing the Use of Intravenous Thrombolytics and Expanding Treatment Options With Intra-arterial and Neuroprotective Therapies

(2011) Gregory W. Albers et al.   STROKE

Delayed transplantation of human neural precursor cells improves outcome from focal cerebral ischemia in aged rats

(2010) Kunlin Jin et al.   AGING CELL

Combinated Transplantation of Neural Stem Cells and Collagen Type I Promote Functional Recovery After Cerebral Ischemia in Rats

(2010) Hongwei Yu et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Use of Transduced Adipose Tissue Stromal Cells as Biologic Minipumps to Deliver Levodopa for the Treatment of Neuropathic Pain: Possibilities and Limitations

(2010) Nuria Cobacho et al.   CELL TRANSPLANTATION

The Organization of the Forelimb Representation of the C57BL/6 Mouse Motor Cortex as Defined by Intracortical Microstimulation and Cytoarchitecture

(2010) Kelly A. Tennant et al.   CEREBRAL CORTEX

Bone Marrow Stromal Cells Enhance Inter- and Intracortical Axonal Connections after Ischemic Stroke in Adult Rats

(2010) Zhongwu Liu et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Reducing excessive GABA-mediated tonic inhibition promotes functional recovery after stroke

(2010) Andrew N. Clarkson et al.   NATURE

An age-related sprouting transcriptome provides molecular control of axonal sprouting after stroke

(2010) Songlin Li et al.   NATURE NEUROSCIENCE

Noninvasive Transplantation of Bone Marrow Stromal Cells for Ischemic Stroke: Preliminary Study With a Thermoreversible Gelation Polymer Hydrogel

(2010) Toshiya Osanai et al.   NEUROSURGERY

Stem Cell Mediation of Functional Recovery after Stroke in the Rat

(2010) Pedro Ramos-Cabrer et al.   PLoS One

Motor Control by Sensory Cortex

(2010) F. Matyas et al.   SCIENCE

The support of neural stem cells transplanted into stroke-induced brain cavities by PLGA particles

(2009) Ellen Bible et al.   BIOMATERIALS

Both compensation and recovery of skilled reaching following small photothrombotic stroke to motor cortex in the rat

(2009) Seong-Keun Moon et al.   EXPERIMENTAL NEUROLOGY

Early Withdrawal of Axons from Higher Centers in Response to Peripheral Somatosensory Denervation

(2009) A. Graziano et al.   JOURNAL OF NEUROSCIENCE

In Vivo Voltage-Sensitive Dye Imaging in Adult Mice Reveals That Somatosensory Maps Lost to Stroke Are Replaced over Weeks by New Structural and Functional Circuits with Prolonged Modes of Activation within Both the Peri-Infarct Zone and Distant Sites

(2009) C. E. Brown et al.   JOURNAL OF NEUROSCIENCE

Treatment of traumatic brain injury in mice with bone marrow stromal cell–impregnated collagen scaffolds

(2009) Changsheng Qu et al.   JOURNAL OF NEUROSURGERY

Plasticity during stroke recovery: from synapse to behaviour

(2009) Timothy H. Murphy et al.   NATURE REVIEWS NEUROSCIENCE

Optimizing the success of cell transplantation therapy for stroke

(2009) Tonya M. Bliss et al.   NEUROBIOLOGY OF DISEASE

Enriched environment promotes efficiency of compensatory movements after cerebral ischemia in rats

(2009) M. Knieling et al.   NEUROSCIENCE

Rapid Morphologic Plasticity of Peri-Infarct Dendritic Spines After Focal Ischemic Stroke

(2008) Craig E. Brown et al.   STROKE

Contralesional Axonal Remodeling of the Corticospinal System in Adult Rats After Stroke and Bone Marrow Stromal Cell Treatment

(2008) Zhongwu Liu et al.   STROKE