TGF-beta1 regulates human brain pericyte inflammatory processes involved in neurovasculature function

Isolation of highly enriched primary human microglia for functional studies

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TGF-β1 prevents blood–brain barrier damage and hemorrhagic transformation after thrombolysis in rats

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Pro-inflammatory TNFα and IL-1β differentially regulate the inflammatory phenotype of brain microvascular endothelial cells

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An anti-inflammatory role for C/EBPδ in human brain pericytes

(2015) Justin Rustenhoven et al.   Scientific Reports

Focal MMP-2 and MMP-9 Activity at the Blood-Brain Barrier Promotes Chemokine-Induced Leukocyte Migration

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Nox4 Is a Major Source of Superoxide Production in Human Brain Pericytes

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p38 MAP kinase mediates transforming-growth factor-β1-induced upregulation of matrix metalloproteinase-9 but not -2 in human brain pericytes

(2014) Yoko Takahashi et al.   BRAIN RESEARCH

Brain capillary pericytes contribute to the immune defense in response to cytokines or LPS in vitro

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Astrocytic TGF-  Signaling Limits Inflammation and Reduces Neuronal Damage during Central Nervous System Toxoplasma Infection

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A role for human brain pericytes in neuroinflammation

(2014) Deidre Jansson et al.   Journal of Neuroinflammation

Tumor necrosis factor-α-stimulated brain pericytes possess a unique cytokine and chemokine release profile and enhance microglial activation

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Matrix Metalloproteinase-2 and Metalloproteinase-9 Activities are Associated with Blood–Brain Barrier Dysfunction in an Animal Model of Severe Sepsis

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Pericyte loss influences Alzheimer-like neurodegeneration in mice

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Neuron-glia crosstalk in health and disease: fractalkine and CX3CR1 take centre stage

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Serum Concentrations of Transforming Growth Factor-Beta 1 in Predicting the Occurrence of Diabetic Retinopathy in Juvenile Patients with Type 1 Diabetes Mellitus

(2013) Katarzyna Zorena et al.   Journal of Diabetes Research

Transforming Growth Factor β-1 Stimulates Profibrotic Epithelial Signaling to Activate Pericyte-Myofibroblast Transition in Obstructive Kidney Fibrosis

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TGF-β as a therapeutic target in high grade gliomas – Promises and challenges

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Amyloid-β-Induced Astrocytic Phagocytosis is Mediated by CD36, CD47 and RAGE

(2012) Raasay S. Jones et al.   Journal of Neuroimmune Pharmacology

Dendritic cell CNS recruitment correlates with disease severity in EAE via CCL2 chemotaxis at the blood–brain barrier through paracellular transmigration and ERK activation

(2012) Divya Sagar et al.   Journal of Neuroinflammation

Matrix Metalloproteinase-2-Mediated Occludin Degradation and Caveolin-1-Mediated Claudin-5 Redistribution Contribute to Blood-Brain Barrier Damage in Early Ischemic Stroke Stage

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Capillary and arteriolar pericytes attract innate leukocytes exiting through venules and 'instruct' them with pattern-recognition and motility programs

(2012) Konstantin Stark et al.   NATURE IMMUNOLOGY

Phagocytic Clearance in Neurodegeneration

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Prostaglandins and Inflammation

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Pericytes: Developmental, Physiological, and Pathological Perspectives, Problems, and Promises

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Brain microvascular pericytes are immunoactive in culture: cytokine, chemokine, nitric oxide, and LRP-1 expression in response to lipopolysaccharide

(2011) Andrej Kovac et al.   Journal of Neuroinflammation

CCL2/MCP-1 modulation of microglial activation and proliferation

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Mechanisms Underlying Inflammation in Neurodegeneration

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Transforming growth factor-β1 induces matrix metalloproteinase-9 and cell migration in astrocytes: roles of ROS-dependent ERK- and JNK-NF-κB pathways

(2010) Hsi-Lung Hsieh et al.   Journal of Neuroinflammation

Pericytes regulate the blood–brain barrier

(2010) Annika Armulik et al.   NATURE

Pericytes are required for blood–brain barrier integrity during embryogenesis

(2010) Richard Daneman et al.   NATURE

Nox4 NADPH oxidase mediates oxidative stress and apoptosis caused by TNF-α in cerebral vascular endothelial cells

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Brain Area-Specific Effect of TGF-β Signaling on Wnt-Dependent Neural Stem Cell Expansion

(2008) Sven Falk et al.   Cell Stem Cell

Brain inflammation initiates seizures

(2008) Jonathan K Kleen et al.   NATURE MEDICINE