Antigen-specific immune reactions to ischemic stroke

The estimated frequency of antiphospholipid antibodies in young adults with cerebrovascular events: a systematic review

(2014) Savino Sciascia et al.   ANNALS OF THE RHEUMATIC DISEASES

Failure of Perivascular Drainage of β-amyloid in Cerebral Amyloid Angiopathy

(2014) Cheryl A. Hawkes et al.   BRAIN PATHOLOGY

Microbial view of central nervous system autoimmunity

(2014) Kerstin Berer et al.   FEBS LETTERS

Oral Tolerance Can Be Established via Gap Junction Transfer of Fed Antigens from CX3CR1+ Macrophages to CD103+ Dendritic Cells

(2014) Elisa Mazzini et al.   IMMUNITY

Immune Suppression via Glucocorticoid-Stimulated Monocytes: A Novel Mechanism To Cope with Inflammation

(2014) G. Varga et al.   JOURNAL OF IMMUNOLOGY

Presence of heat shock protein 70 in secondary lymphoid tissue correlates with stroke prognosis

(2014) Manuel Gómez-Choco et al.   JOURNAL OF NEUROIMMUNOLOGY

Ischemic neurons recruit natural killer cells that accelerate brain infarction

(2014) Y. Gan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Essential Role of Program Death 1-Ligand 1 in Regulatory T-Cell–Afforded Protection Against Blood–Brain Barrier Damage After Stroke

(2014) Peiying Li et al.   STROKE

Fingolimod for the Treatment of Intracerebral Hemorrhage

(2014) Ying Fu et al.   JAMA Neurology

Regulatory T Cells as Immunotherapy

(2014) Benjamin D. Singer et al.   Frontiers in Immunology

Immunological consequences of ischemic stroke

(2013) A. Vogelgesang et al.   ACTA NEUROLOGICA SCANDINAVICA

Interstitial fluid drainage is impaired in ischemic stroke and Alzheimer’s disease mouse models

(2013) Michal Arbel-Ornath et al.   ACTA NEUROPATHOLOGICA

Afferent and efferent immunological pathways of the brain. Anatomy, Function and Failure

(2013) R.O. Carare et al.   BRAIN BEHAVIOR AND IMMUNITY

Carcinoembryonic Antigen–Related Cell Adhesion Molecule 1 Inhibits MMP-9–Mediated Blood–Brain–Barrier Breakdown in a Mouse Model for Ischemic Stroke

(2013) Peter Ludewig et al.   CIRCULATION RESEARCH

B-regulatory cells in autoimmunity and immune mediated inflammation

(2013) Zahava Vadasz et al.   FEBS LETTERS

Virus infection, antiviral immunity, and autoimmunity

(2013) Daniel R. Getts et al.   IMMUNOLOGICAL REVIEWS

IL-10 Deficiency Exacerbates the Brain Inflammatory Response to Permanent Ischemia without Preventing Resolution of the Lesion

(2013) Isabel Pérez-de Puig et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Early Inhibition of MMP Activity in Ischemic Rat Brain Promotes Expression of Tight Junction Proteins and Angiogenesis During Recovery

(2013) Yi Yang et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Superiority of Preventive Antibiotic Treatment Compared with Standard Treatment of Poststroke Pneumonia in Experimental Stroke: A Bed to Bench Approach

(2013) Susann Hetze et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

 2-Adrenoreceptor Agonist Inhibits Antigen Cross-Presentation by Dendritic Cells

(2013) J. Herve et al.   JOURNAL OF IMMUNOLOGY

PD-L1 enhances CNS inflammation and infarct volume following experimental stroke in mice in opposition to PD-1

(2013) Sheetal Bodhankar et al.   Journal of Neuroinflammation

Boosting Regulatory T Cells Limits Neuroinflammation in Permanent Cortical Stroke

(2013) A. Liesz et al.   JOURNAL OF NEUROSCIENCE

IL-10-producing B-cells limit CNS inflammation and infarct volume in experimental stroke

(2013) Sheetal Bodhankar et al.   METABOLIC BRAIN DISEASE

Atorvastatin-modified dendritic cells in vitro ameliorate experimental autoimmune myasthenia gravis by up-regulated Treg cells and shifted Th1/Th17 to Th2 cytokines

(2013) Xiao-Li Li et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Neuropsychiatric disease relevance of circulating anti-NMDA receptor autoantibodies depends on blood–brain barrier integrity

(2013) C Hammer et al.   MOLECULAR PSYCHIATRY

Plasma levels of neuron specific enolase quantify the extent of neuronal injury in murine models of ischemic stroke and multiple sclerosis

(2013) Mathias Gelderblom et al.   NEUROBIOLOGY OF DISEASE

The Relationship between Cortical Blood Flow and Sub-Cortical White-Matter Health across the Adult Age Span

(2013) J. Jean Chen et al.   PLoS One

Mechanisms of Cognitive Impairment in Cerebral Small Vessel Disease: Multimodal MRI Results from the St George's Cognition and Neuroimaging in Stroke (SCANS) Study

(2013) Andrew J. Lawrence et al.   PLoS One

Adoptive Regulatory T-Cell Therapy Preserves Systemic Immune Homeostasis After Cerebral Ischemia

(2013) Peiying Li et al.   STROKE

Fingolimod Reduces Hemorrhagic Transformation Associated With Delayed Tissue Plasminogen Activator Treatment in a Mouse Thromboembolic Model

(2013) Francisco Campos et al.   STROKE

FTY720 Ameliorates Acute Ischemic Stroke in Mice by Reducing Thrombo-Inflammation but Not by Direct Neuroprotection

(2013) Peter Kraft et al.   STROKE

The MHC I loading complex: a multitasking machinery in adaptive immunity

(2013) Sabine Hulpke et al.   TRENDS IN BIOCHEMICAL SCIENCES

B7 family checkpoint regulators in immune regulation and disease

(2013) Sabrina Ceeraz et al.   TRENDS IN IMMUNOLOGY

The relationship between osteoarthritis and cardiovascular disease in a population health survey: a cross-sectional study

(2013) M Mushfiqur Rahman et al.   BMJ Open

Adoptive regulatory T-cell therapy protects against cerebral ischemia

(2012) Peiying Li et al.   ANNALS OF NEUROLOGY

Evidence of Intrathecal Immunoglobulin Synthesis in Stroke

(2012) Harald Prüss et al.   ARCHIVES OF NEUROLOGY

Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature

(2012) C. Kleinschnitz et al.   BLOOD

Immune mechanisms of stroke

(2012) Tim Magnus et al.   CURRENT OPINION IN NEUROLOGY

In vivo imaging of induction of heat-shock protein-70 gene expression with fluorescence reflectance imaging and intravital confocal microscopy following brain ischaemia in reporter mice

(2012) Xavier de la Rosa et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Inducible Heat Shock Protein 70 Reduces T Cell Responses and Stimulatory Capacity of Monocyte-derived Dendritic Cells

(2012) Pawel Stocki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulatory T Cells Accumulate and Proliferate in the Ischemic Hemisphere for up to 30 Days after MCAO

(2012) Tobias Stubbe et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Brain-Derived Antigens in Lymphoid Tissue of Patients with Acute Stroke

(2012) A. M. Planas et al.   JOURNAL OF IMMUNOLOGY

Impact of infections on long-term outcome after severe middle cerebral artery infarction

(2012) Lena Ulm et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Intrastriatal B-cell administration limits infarct size after stroke in B-cell deficient mice

(2012) Yingxin Chen et al.   METABOLIC BRAIN DISEASE

The immunology of acute stroke

(2012) Ángel Chamorro et al.   Nature Reviews Neurology

HSP70 Enhances Immunosuppressive Function of CD4+CD25+FoxP3+ T Regulatory Cells and Cytotoxicity in CD4+CD25− T Cells

(2012) Julian Wachstein et al.   PLoS One

Autoimmune Responses to Brain Following Stroke

(2012) Kyra Becker   Translational Stroke Research

Perivascular drainage of solutes is impaired in the ageing mouse brain and in the presence of cerebral amyloid angiopathy

(2011) Cheryl A. Hawkes et al.   ACTA NEUROPATHOLOGICA

Abnormal functional connectivity in patients with vascular cognitive impairment, no dementia: A resting-state functional magnetic resonance imaging study

(2011) Ya-wen Sun et al.   BEHAVIOURAL BRAIN RESEARCH

Post-stroke infection: A systematic review and meta-analysis

(2011) Willeke F Westendorp et al.   BMC Neurology

Oral tolerance

(2011) Howard L. Weiner et al.   IMMUNOLOGICAL REVIEWS

Regulatory B Cells Limit CNS Inflammation and Neurologic Deficits in Murine Experimental Stroke

(2011) X. Ren et al.   JOURNAL OF NEUROSCIENCE

Therapy with recombinant T-cell receptor ligand reduces infarct size and infiltrating inflammatory cells in brain after middle cerebral artery occlusion in mice

(2011) Suzan Dziennis et al.   METABOLIC BRAIN DISEASE

The immunology of stroke: from mechanisms to translation

(2011) Costantino Iadecola et al.   NATURE MEDICINE

FTY720 Reduces Post-Ischemic Brain Lymphocyte Influx but Does Not Improve Outcome in Permanent Murine Cerebral Ischemia

(2011) Arthur Liesz et al.   PLoS One

Heat shock protein 90 (HSP90) contributes to cytosolic translocation of extracellular antigen for cross-presentation by dendritic cells

(2011) T. Imai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Blood–Brain Barrier Breakdown in Acute and Chronic Cerebrovascular Disease

(2011) Yi Yang et al.   STROKE

Programmed Death-1 Pathway Limits Central Nervous System Inflammation and Neurologic Deficits in Murine Experimental Stroke

(2011) Xuefang Ren et al.   STROKE

Hospitalization for Infection and Risk of Acute Ischemic Stroke

(2011) Mitchell S.V. Elkind et al.   STROKE

Influenza Virus Infection Aggravates Stroke Outcome

(2011) Sajjad Muhammad et al.   STROKE

Association Between Stroke and Patients With Pelvic Inflammatory Disease

(2011) Po-Chih Chen et al.   STROKE

Autoimmune Responses to the Brain After Stroke Are Associated With Worse Outcome

(2011) Kyra J. Becker et al.   STROKE

Fingolimod provides long-term protection in rodent models of cerebral ischemia

(2010) Ying Wei et al.   ANNALS OF NEUROLOGY

Early detrimental T-cell effects in experimental cerebral ischemia are neither related to adaptive immunity nor thrombus formation

(2010) C. Kleinschnitz et al.   BLOOD

Myelin antigen reactive T cells in cerebrovascular diseases

(2010) W. Z. WANG et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Dendritic cells in tolerance induction for the treatment of autoimmune diseases

(2010) Maria Rescigno   EUROPEAN JOURNAL OF IMMUNOLOGY

Immunological consequences of ischemic stroke: Immunosuppression and autoimmunity

(2010) Antje Vogelgesang et al.   JOURNAL OF NEUROIMMUNOLOGY

Chronic Systemic Infection Exacerbates Ischemic Brain Damage via a CCL5 (Regulated on Activation, Normal T-Cell Expressed and Secreted)-Mediated Proinflammatory Response in Mice

(2010) A. Denes et al.   JOURNAL OF NEUROSCIENCE

NR2 antibodies: Risk assessment of transient ischemic attack (TIA)/stroke in patients with history of isolated and multiple cerebrovascular events

(2010) Joseph D. Weissman et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Myelination and support of axonal integrity by glia

(2010) Klaus-Armin Nave   NATURE

Change in the Brain's White Matter

(2010) R. D. Fields   SCIENCE

Brain dendritic cells in ischemic stroke: Time course, activation state, and origin

(2009) Jennifer C. Felger et al.   BRAIN BEHAVIOR AND IMMUNITY

Medical complications after stroke

(2009) Sandeep Kumar et al.   LANCET NEUROLOGY

Regulatory T cells are key cerebroprotective immunomodulators in acute experimental stroke

(2009) Arthur Liesz et al.   NATURE MEDICINE

CNS Immune Responses Following Experimental Stroke

(2009) Dannielle Zierath et al.   Neurocritical Care

Monocytes Are Major Players in the Prognosis and Risk of Infection After Acute Stroke

(2009) Xabier Urra et al.   STROKE

Infarct Volume is a Major Determiner of Post-Stroke Immune Cell Function and Susceptibility to Infection

(2009) Andreas Hug et al.   STROKE

Temporal and Spatial Dynamics of Cerebral Immune Cell Accumulation in Stroke

(2009) Mathias Gelderblom et al.   STROKE

Recombinant T Cell Receptor Ligand Treats Experimental Stroke

(2009) Sandhya Subramanian et al.   STROKE

Stroke-Induced Immunodepression Is a Marker of Severe Brain Damage

(2009) Xabier Urra et al.   STROKE

Activation of Sphingosine 1-Phosphate Receptor-1 by FTY720 Is Neuroprotective After Ischemic Stroke in Rats

(2009) Yu Hasegawa et al.   STROKE

Lymphatic drainage of the brain and the pathophysiology of neurological disease

(2008) Roy O. Weller et al.   ACTA NEUROPATHOLOGICA

Human regulatory T cells and autoimmunity

(2008) Cristina M. Costantino et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

S1P1 Receptor Signaling Overrides Retention Mediated by Gαi-Coupled Receptors to Promote T Cell Egress

(2008) Trung H.M. Pham et al.   IMMUNITY

Brain antigens in functionally distinct antigen-presenting cell populations in cervical lymph nodes in MS and EAE

(2008) Marloes van Zwam et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Mucosal tolerance to E-selectin provides protection against cerebral ischemia–reperfusion injury in rats

(2008) Wu Yun et al.   JOURNAL OF NEUROIMMUNOLOGY

Systemic Inflammation Alters the Kinetics of Cerebrovascular Tight Junction Disruption after Experimental Stroke in Mice

(2008) B. W. McColl et al.   JOURNAL OF NEUROSCIENCE

Acute ischaemic stroke and infection: recent and emerging concepts

(2008) Hedley CA Emsley et al.   LANCET NEUROLOGY

Solutes, but not cells, drain from the brain parenchyma along basement membranes of capillaries and arteries: significance for cerebral amyloid angiopathy and neuroimmunology

(2008) R. O. Carare et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Sensitization and tolerization to brain antigens in stroke

(2008) K.J. Becker   NEUROSCIENCE

Harms and benefits of lymphocyte subpopulations in patients with acute stroke

(2008) X. Urra et al.   NEUROSCIENCE

Stroke-induced immunodepression and post-stroke infections: Lessons from the preventive antibacterial therapy in stroke trial

(2008) J. Klehmet et al.   NEUROSCIENCE

Protective autoimmunity in the nervous system

(2008) Jerome J. Graber et al.   PHARMACOLOGY & THERAPEUTICS

Regulation of Dendritic Cell Migration by CD74, the MHC Class II-Associated Invariant Chain

(2008) G. Faure-Andre et al.   SCIENCE

Identification of Variations in Blood-Brain Barrier Opening After Cerebral Ischemia by Dual Contrast-Enhanced Magnetic Resonance Imaging and T 1sat Measurements

(2008) Tavarekere N. Nagaraja et al.   STROKE

Analysis of Lymphocyte Subsets in Patients With Stroke and Their Influence on Infection After Stroke

(2007) Antje Vogelgesang et al.   STROKE