Diffuse axonal injury in brain trauma: insights from alterations in neurofilaments

Axoplasmic reticulum Ca2+release causes secondary degeneration of spinal axons

(2014) David P. Stirling et al.   ANNALS OF NEUROLOGY

Acute mild traumatic brain injury is not associated with white matter change on diffusion tensor imaging

(2014) Tero Ilvesmäki et al.   BRAIN

The role of calpains in traumatic brain injury

(2014) Shuang Liu et al.   BRAIN INJURY

Knockdown of STIM1 Improves Neuronal Survival After Traumatic Neuronal Injury Through Regulating mGluR1-Dependent Ca2+ Signaling in Mouse Cortical Neurons

(2014) Peng-Fei Hou et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

In vitro and in situ visualization of cytoskeletal deformation under load: traumatic axonal injury

(2014) Adam J. Fournier et al.   FASEB JOURNAL

Divergent and convergent roles for kinases and phosphatases in neurofilament dynamics

(2014) S. Lee et al.   JOURNAL OF CELL SCIENCE

Local Regulation of Neurofilament Transport by Myelinating Cells

(2014) P. C. Monsma et al.   JOURNAL OF NEUROSCIENCE

Detection of neurofilament-H in serum as a diagnostic tool to predict injury severity in patients who have suffered mild traumatic brain injury

(2014) Joshua W. Gatson et al.   JOURNAL OF NEUROSURGERY

Monitoring concussion in a knocked-out boxer by CSF biomarker analysis

(2014) Sanna Neselius et al.   KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY

Mitochondria-mediated apoptosis in mammals

(2014) Shunbin Xiong et al.   Protein & Cell

Mild traumatic brain injury in the mouse induces axotomy primarily within the axon initial segment

(2013) John E. Greer et al.   ACTA NEUROPATHOLOGICA

The neuropathology of sport

(2013) Ann C. McKee et al.   ACTA NEUROPATHOLOGICA

Biomarkers for the Clinical Differential Diagnosis in Traumatic Brain Injury-A Systematic Review

(2013) Shoji Yokobori et al.   CNS Neuroscience & Therapeutics

The pathophysiology of traumatic brain injury at a glance

(2013) M. Prins et al.   Disease Models & Mechanisms

Role of calpains in the injury-induced dysfunction and degeneration of the mammalian axon

(2013) Marek Ma   NEUROBIOLOGY OF DISEASE

The neuropsychological outcomes of concussion: A systematic review of meta-analyses on the cognitive sequelae of mild traumatic brain injury.

(2013) Justin E. Karr et al.   NEUROPSYCHOLOGY

Increased Neurofilament Light Chain Blood Levels in Neurodegenerative Neurological Diseases

(2013) Johanna Gaiottino et al.   PLoS One

Mathematical Models of Blast-Induced TBI: Current Status, Challenges, and Prospects

(2013) Raj K. Gupta et al.   Frontiers in Neurology

Excitotoxin-induced caspase-3 activation and microtubule disintegration in axons is inhibited by taxol

(2013) Anna King et al.   Acta Neuropathologica Communications

Chronic Excitotoxin-Induced Axon Degeneration in a Compartmented Neuronal Culture Model

(2012) Katherine A Hosie et al.   ASN Neuro

Impaired axoplasmic transport is the dominant injury induced by an impact acceleration injury device: An analysis of traumatic axonal injury in pyramidal tract and corpus callosum of rats

(2012) Srinivasu Kallakuri et al.   BRAIN RESEARCH

Axonal pathology in traumatic brain injury

(2012) Victoria E. Johnson et al.   EXPERIMENTAL NEUROLOGY

Neurofilaments at a glance

(2012) A. Yuan et al.   JOURNAL OF CELL SCIENCE

Differential Effects of FK506 on Structural and Functional Axonal Deficits After Diffuse Brain Injury in the Immature Rat

(2012) Ann Mae DiLeonardi et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Calpastatin Overexpression Protects Axonal Transport in an In Vivo Model of Traumatic Axonal Injury

(2012) Marek Ma et al.   JOURNAL OF NEUROTRAUMA

Therapy Development for Diffuse Axonal Injury

(2012) Douglas H. Smith et al.   JOURNAL OF NEUROTRAUMA

Assembly of a new growth cone after axotomy: the precursor to axon regeneration

(2012) Frank Bradke et al.   NATURE REVIEWS NEUROSCIENCE

The Neuropathology and Neurobiology of Traumatic Brain Injury

(2012) Kaj Blennow et al.   NEURON

ERK1/2 MAP kinases: Structure, function, and regulation

(2012) Robert Roskoski   PHARMACOLOGICAL RESEARCH

Comment on "Chronic Traumatic Encephalopathy in Blast-Exposed Military Veterans and a Blast Neurotrauma Mouse Model"

(2012) M. Tisdall et al.   Science Translational Medicine

Phosphorylated neurofilament subunit NF-H as a biomarker for evaluating the severity of spinal cord injury patients, a pilot study

(2012) K Hayakawa et al.   SPINAL CORD

The usefulness of S100B, NSE, GFAP, NF-H, secretagogin and Hsp70 as a predictive biomarker of outcome in children with traumatic brain injury

(2011) Jiří Žurek et al.   ACTA NEUROCHIRURGICA

Hyperphosphorylated neurofilament NF-H as a predictor of mortality after brain injury in children

(2011) Jiří Žurek et al.   BRAIN INJURY

Cytoarchitecture of the mouse neocortex revealed by the low-molecular-weight neurofilament protein subunit

(2011) Melissa Paulussen et al.   Brain Structure & Function

Partial interruption of axonal transport due to microtubule breakage accounts for the formation of periodic varicosities after traumatic axonal injury

(2011) Min D. Tang-Schomer et al.   EXPERIMENTAL NEUROLOGY

Genu of corpus callosum as a prognostic factor in diffuse axonal injury

(2011) Hidetoshi Matsukawa et al.   JOURNAL OF NEUROSURGERY

Concussive Brain Trauma in the Mouse Results in Acute Cognitive Deficits and Sustained Impairment of Axonal Function

(2011) Jennifer A. Creed et al.   JOURNAL OF NEUROTRAUMA

Time-Dependent Changes in Serum Biomarker Levels after Blast Traumatic Brain Injury

(2011) Andrea Gyorgy et al.   JOURNAL OF NEUROTRAUMA

Traumatic Axonal Injury in the Optic Nerve: Evidence for Axonal Swelling, Disconnection, Dieback, and Reorganization

(2011) Jiaqiong Wang et al.   JOURNAL OF NEUROTRAUMA

Mild Traumatic Brain Injury and Diffuse Axonal Injury in Swine

(2011) Kevin D. Browne et al.   JOURNAL OF NEUROTRAUMA

Selective Vulnerability of Non-Myelinated Axons to Stretch Injury in an In Vitro Co-Culture System

(2011) Jerome A. Staal et al.   JOURNAL OF NEUROTRAUMA

Oxidative stress caused by mitochondrial calcium overload

(2010) Tsung-I Peng et al.   Annals of the New York Academy of Sciences

The Molecular Pathophysiology of Concussive Brain Injury

(2010) Garni Barkhoudarian et al.   CLINICS IN SPORTS MEDICINE

Phosphorylation-Mediated Conformational Changes in the Mouse Neurofilament Architecture: Insight from a Neurofilament Brush Model

(2010) William Stevenson et al.   JOURNAL OF MOLECULAR BIOLOGY

Involvement of ERK2 in traumatic spinal cord injury

(2010) Chen-Guang Yu et al.   JOURNAL OF NEUROCHEMISTRY

Mild Fluid Percussion Injury in Mice Produces Evolving Selective Axonal Pathology and Cognitive Deficits Relevant to Human Brain Injury

(2010) Aisling Spain et al.   JOURNAL OF NEUROTRAUMA

Cell mechanics and the cytoskeleton

(2010) Daniel A. Fletcher et al.   NATURE

Calpain as a therapeutic target in traumatic brain injury

(2010) Kathryn E. Saatman et al.   Neurotherapeutics

Mechanisms of acute axonal degeneration in the optic nerve in vivo

(2010) J. Knoferle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biomarkers Associated With Diffuse Traumatic Axonal Injury: Exploring Pathogenesis, Early Diagnosis, and Prognosis

(2010) Jia Li et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Impaired axonal transport and neurofilament compaction occur in separate populations of injured axons following diffuse brain injury in the immature rat

(2009) Ann Mae DiLeonardi et al.   BRAIN RESEARCH

Mechanical membrane injury induces axonal beading through localized activation of calpain

(2009) Devrim Kilinc et al.   EXPERIMENTAL NEUROLOGY

Local calcium-dependent mechanisms determine whether a cut axonal end assembles a retarded endbulb or competent growth cone

(2009) Dotan Kamber et al.   EXPERIMENTAL NEUROLOGY

Mechanical breaking of microtubules in axons during dynamic stretch injury underlies delayed elasticity, microtubule disassembly, and axon degeneration

(2009) Min D. Tang-Schomer et al.   FASEB JOURNAL

Structural Properties of Neurofilament Sidearms: Sequence-Based Modeling of Neurofilament Architecture

(2009) Rakwoo Chang et al.   JOURNAL OF MOLECULAR BIOLOGY

Initial calcium release from intracellular stores followed by calcium dysregulation is linked to secondary axotomy following transient axonal stretch injury

(2009) Jerome A. Staal et al.   JOURNAL OF NEUROCHEMISTRY

Neurofilaments Form a Highly Stable Stationary Cytoskeleton after Reaching a Critical Level in Axons

(2009) A. Yuan et al.   JOURNAL OF NEUROSCIENCE

Prevalence and impact of diffuse axonal injury in patients with moderate and severe head injury: a cohort study of early magnetic resonance imaging findings and 1-year outcome

(2009) Toril Skandsen et al.   JOURNAL OF NEUROSURGERY

A Panel of Neuron-Enriched Proteins as Markers for Traumatic Brain Injury in Humans

(2009) Robert Siman et al.   JOURNAL OF NEUROTRAUMA

Calpain Inhibition Reduces Axolemmal Leakage in Traumatic Axonal Injury

(2009) Endre Czeiter et al.   MOLECULES

Induction of corticospinal regeneration by lentiviral trkB-induced Erk activation

(2009) E. R. Hollis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of neurofilament dynamics by phosphorylation

(2008) Thomas B. Shea et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

The Phosphorylated Axonal Form of the Neurofilament Subunit NF-H (pNF-H) as a Blood Biomarker of Traumatic Brain Injury

(2008) Kevin J. Anderson et al.   JOURNAL OF NEUROTRAUMA

Moderate and severe traumatic brain injury in adults

(2008) Andrew IR Maas et al.   LANCET NEUROLOGY

Review of the Multiple Aspects of Neurofilament Functions, and their Possible Contribution to Neurodegeneration

(2008) Rodolphe Perrot et al.   MOLECULAR NEUROBIOLOGY

NG2 cells response to axonal alteration in the spinal cord white matter in mice with genetic disruption of neurofilament light subunit expression

(2008) Ya Wu et al.   Molecular Neurodegeneration