5-HT7 receptors as modulators of neuronal excitability, synaptic transmission and plasticity: physiological role and possible implications in autism spectrum disorders

Channelopathies and dendritic dysfunction in fragile X syndrome

(2014) Darrin H. Brager et al.   BRAIN RESEARCH BULLETIN

Acute and repeated treatment with the 5-HT7 receptor antagonist SB 269970 induces functional desensitization of 5-HT7 receptors in rat hippocampus

(2014) Krzysztof Tokarski et al.   Pharmacological Reports

Modulatory effects following subchronic stimulation of brain 5-HT7-R system in mice and rats

(2014) Emilia Romano et al.   REVIEWS IN THE NEUROSCIENCES

The role of serotonin 5-HT7 receptor in regulating sleep and wakefulness

(2014) Jaime M. Monti et al.   REVIEWS IN THE NEUROSCIENCES

Selective agonists for serotonin 7 (5-HT7) receptor and their applications in preclinical models: an overview

(2014) Pantaleo Di Pilato et al.   REVIEWS IN THE NEUROSCIENCES

Serotonin Hypothesis of Autism: Implications for Selective Serotonin Reuptake Inhibitor Use during Pregnancy

(2013) Rebecca A. Harrington et al.   Autism Research

Reduced Serotonin Receptor Subtypes in a Limbic and a Neocortical Region in Autism

(2013) Adrian Oblak et al.   Autism Research

Amisulpride promotes cognitive flexibility in rats: The role of 5-HT7 receptors

(2013) Agnieszka Nikiforuk et al.   BEHAVIOURAL BRAIN RESEARCH

Systemic administration and local microinjection into the central nervous system of the 5-HT7 receptor agonist LP-211 modify the sleep-wake cycle in the rat

(2013) Jaime M. Monti et al.   BEHAVIOURAL BRAIN RESEARCH

Palmitoylation of serotonin receptors

(2013) Nataliya Gorinski et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Functional expression of 5-HT7 receptor on the substantia gelatinosa neurons of the trigeminal subnucleus caudalis in mice

(2013) Eun Ju Yang et al.   BRAIN RESEARCH

Multiple roles of serotonin in pain control mechanisms —Implications of 5-HT7 and other 5-HT receptor types

(2013) Florent Viguier et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Vortioxetine for major depressive disorder: a systematic review of the efficacy and safety profile for this newly approved antidepressant - what is the number needed to treat, number needed to harm and likelihood to be helped or harmed?

(2013) L. Citrome   INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

5-Hydroxytryptamine type 7 receptor neuroprotection against NMDA-induced excitotoxicity is PDGFβ receptor dependent

(2013) Maryam S. Vasefi et al.   JOURNAL OF NEUROCHEMISTRY

Serotonergic Modulation of Neuronal Activity in the Nucleus Accumbens Following Repeated Methamphetamine Administration in Rats

(2013) Kumatoshi Ishihara et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Social reward requires coordinated activity of nucleus accumbens oxytocin and serotonin

(2013) Gül Dölen et al.   NATURE

Antidepressant and anxiolytic potential of the multimodal antidepressant vortioxetine (Lu AA21004) assessed by behavioural and neurogenesis outcomes in mice

(2013) Jean-Philippe Guilloux et al.   NEUROPHARMACOLOGY

Peripheral and spinal 5-HT receptors participate in the pronociceptive and antinociceptive effects of fluoxetine in rats

(2013) C. Cervantes-Durán et al.   NEUROSCIENCE

Serotonin 1A, 1B, and 7 receptors of the rat medial nucleus accumbens differentially regulate feeding, water intake, and locomotor activity

(2013) Kara A. Clissold et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

The neural and genetic basis of executive function: Attention, cognitive flexibility, and response inhibition

(2013) Sheree F. Logue et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Effects of the Selective 5-HT7 Receptor Antagonist SB-269970 and Amisulpride on Ketamine-Induced Schizophrenia-like Deficits in Rats

(2013) Agnieszka Nikiforuk et al.   PLoS One

Modulation of 5-HT7 receptor: effect on object recognition performances in mice

(2013) Thomas Freret et al.   PSYCHOPHARMACOLOGY

5-HT systems: emergent targets for memory formation and memory alterations

(2013) Alfredo Meneses   REVIEWS IN THE NEUROSCIENCES

Emotional and risk seeking behavior after prepuberal subchronic or adult acute stimulation of 5-HT7-Rs in naples high excitability rats

(2013) Lucia A. Ruocco et al.   SYNAPSE

Lack of serotonin reuptake during brain development alters rostral raphe-prefrontal network formation

(2013) Josefine S. Witteveen et al.   Frontiers in Cellular Neuroscience

Lurasidone as a potential therapy for bipolar disorder

(2013) Won-Myong Bahk et al.   Neuropsychiatric Disease and Treatment

The serotonin 5-HT7 receptors: two decades of research

(2013) Evelien Gellynck et al.   EXPERIMENTAL BRAIN RESEARCH

Hyperpolarization-activated cation current Ih of dentate gyrus granule cells is upregulated in human and rat temporal lobe epilepsy

(2012) Rainer Surges et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Activation of 5-HT7 Serotonin Receptors Reverses Metabotropic Glutamate Receptor-Mediated Synaptic Plasticity in Wild-Type and Fmr1 Knockout Mice, a Model of Fragile X Syndrome

(2012) Lara Costa et al.   BIOLOGICAL PSYCHIATRY

Involvement of 5-HT7 receptors in the pathogenesis of temporal lobe epilepsy

(2012) Zhiyong Yang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Heterodimerization of serotonin receptors 5-HT1A and 5-HT7 differentially regulates receptor signalling and trafficking

(2012) U. Renner et al.   JOURNAL OF CELL SCIENCE

5-HT7R/G12 Signaling Regulates Neuronal Morphology and Function in an Age-Dependent Manner

(2012) F. Kobe et al.   JOURNAL OF NEUROSCIENCE

Serotonin in the Modulation of Neural Plasticity and Networks: Implications for Neurodevelopmental Disorders

(2012) Klaus-Peter Lesch et al.   NEURON

GABA, but not opioids, mediates the anti-hyperalgesic effects of 5-HT7 receptor activation in rats suffering from neuropathic pain

(2012) Florent Viguier et al.   NEUROPHARMACOLOGY

5-HT1A and 5-HT7 receptor crosstalk in the regulation of emotional memory: Implications for effects of selective serotonin reuptake inhibitors

(2012) Therese M. Eriksson et al.   NEUROPHARMACOLOGY

The serotonin receptor 7 promotes neurite outgrowth via ERK and Cdk5 signaling pathways

(2012) L. Speranza et al.   NEUROPHARMACOLOGY

Microinjection of the 5-HT7 receptor antagonist SB-269970 into the rat brainstem and basal forebrain: Site-dependent effects on REM sleep

(2012) Jaime M. Monti et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Mice Genetically Depleted of Brain Serotonin Display Social Impairments, Communication Deficits and Repetitive Behaviors: Possible Relevance to Autism

(2012) Michael J. Kane et al.   PLoS One

Autism gene variant causes hyperserotonemia, serotonin receptor hypersensitivity, social impairment and repetitive behavior

(2012) J. Veenstra-VanderWeele et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synapse dysfunction in autism: a molecular medicine approach to drug discovery in neurodevelopmental disorders

(2012) Will Spooren et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Impaired Dendritic Expression and Plasticity of h-Channels in the fmr1−/y Mouse Model of Fragile X Syndrome

(2012) Darrin H. Brager et al.   Cell Reports

Discrimination learning and attentional set formation in a mouse model of Fragile X.

(2011) Kimberly S. Casten et al.   BEHAVIORAL NEUROSCIENCE

Selective blockade of 5-HT7 receptors facilitates attentional set-shifting in stressed and control rats

(2011) Agnieszka Nikiforuk   BEHAVIOURAL BRAIN RESEARCH

5-HT and the immune system

(2011) Gerard P Ahern   CURRENT OPINION IN PHARMACOLOGY

5-HT1A and 5-HT7 receptors differently modulate AMPA receptor-mediated hippocampal synaptic transmission

(2011) L. Costa et al.   HIPPOCAMPUS

The 5-HT7 receptor in learning and memory

(2011) Amanda J. Roberts et al.   HIPPOCAMPUS

Rapid Loss of Dendritic HCN Channel Expression in Hippocampal Pyramidal Neurons following Status Epilepticus

(2011) S. Jung et al.   JOURNAL OF NEUROSCIENCE

Spinal 5-HT7 receptor activation induces long-lasting phrenic motor facilitation

(2011) M. S. Hoffman et al.   JOURNAL OF PHYSIOLOGY-LONDON

Role of the 5-HT7 Receptor in the Central Nervous System: from Current Status to Future Perspectives

(2011) Anne Matthys et al.   MOLECULAR NEUROBIOLOGY

Increased serotonin axons (immunoreactive to 5-HT transporter) in postmortem brains from young autism donors

(2011) Efrain C. Azmitia et al.   NEUROPHARMACOLOGY

On the role of brain 5-HT7 receptor in the mechanism of hypothermia: Comparison with hypothermia mediated via 5-HT1A and 5-HT3 receptor

(2011) Vladimir S. Naumenko et al.   NEUROPHARMACOLOGY

Modulatory effects of two novel agonists for serotonin receptor 7 on emotion, motivation and circadian rhythm profiles in mice

(2011) Walter Adriani et al.   NEUROPHARMACOLOGY

Pharmacological Blockade of 5-HT7 Receptors as a Putative Fast Acting Antidepressant Strategy

(2011) Ouissame Mnie-Filali et al.   NEUROPSYCHOPHARMACOLOGY

A new approach for studying GPCR dimers: Drug-induced inactivation and reactivation to reveal GPCR dimer function in vitro, in primary culture, and in vivo

(2011) Milt Teitler et al.   PHARMACOLOGY & THERAPEUTICS

Genetic-Background Modulation of Core and Variable Autistic-Like Symptoms in Fmr1 Knock-Out Mice

(2011) Susanna Pietropaolo et al.   PLoS One

The 5-HT 2A receptor and serotonin transporter in Asperger's Disorder: A PET study with [ 11 C]MDL 100907 and [ 11 C]DASB

(2011) Ragy R. Girgis et al.   PSYCHIATRY RESEARCH-NEUROIMAGING

Spinal 5-HT7 Receptors Play an Important Role in the Antinociceptive and Antihyperalgesic Effects of Tramadol and Its Metabolite, O-Desmethyltramadol, via Activation of Descending Serotonergic Pathways

(2010) Omer Yanarates et al.   ANESTHESIOLOGY

The 5-HT7 receptor as a mediator and modulator of antidepressant-like behavior

(2010) Gor Sarkisyan et al.   BEHAVIOURAL BRAIN RESEARCH

Group 1 mGluR-Dependent Synaptic Long-Term Depression: Mechanisms and Implications for Circuitry and Disease

(2010) Christian Lüscher et al.   NEURON

Critical brain circuits at the intersection between stress and learning

(2010) Debra A. Bangasser et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Fetal exposure to teratogens: Evidence of genes involved in autism

(2010) Diane Dufour-Rainfray et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

LP-211 is a brain penetrant selective agonist for the serotonin 5-HT7 receptor

(2010) Peter B. Hedlund et al.   NEUROSCIENCE LETTERS

G Protein - Mediated Signaling: Same Receptor, Multiple Effectors

(2010) Andrew Woehler et al.   Current Molecular Pharmacology

The 5-HT7 receptor is involved in allocentric spatial memory information processing

(2009) Gor Sarkisyan et al.   BEHAVIOURAL BRAIN RESEARCH

Constitutive Gs-mediated, but not G12-mediated, activity of the 5-hydroxytryptamine 5-HT7(a) receptor is modulated by the palmitoylation of its C-terminal domain

(2009) Elena Kvachnina et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Spinal 5-HT7 Receptors Are Critical for Alternating Activity During Locomotion: In Vitro Neonatal and In Vivo Adult Studies Using 5-HT7 Receptor Knockout Mice

(2009) Jun Liu et al.   JOURNAL OF NEUROPHYSIOLOGY

5-HT7 receptor activation inhibits mechanical hypersensitivity secondary to capsaicin sensitization in mice

(2009) Alex Brenchat et al.   PAIN

Learning-related postburst afterhyperpolarization reduction in CA1 pyramidal neurons is mediated by protein kinase A

(2009) M. M. Oh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amisulpride is a potent 5-HT7 antagonist: relevance for antidepressant actions in vivo

(2009) Atheir I. Abbas et al.   PSYCHOPHARMACOLOGY

The 5-HT7 receptor and disorders of the nervous system: an overview

(2009) Peter B. Hedlund   PSYCHOPHARMACOLOGY

More than synaptic plasticity: role of nonsynaptic plasticity in learning and memory

(2009) Riccardo Mozzachiodi et al.   TRENDS IN NEUROSCIENCES

Molecular biology of 5-HT receptors

(2008) Jason Hannon et al.   BEHAVIOURAL BRAIN RESEARCH

Effect of 5-HT7 antagonist SB-269970 in the modulation of working and reference memory in the rat

(2008) Antonella Gasbarri et al.   BEHAVIOURAL BRAIN RESEARCH

The serotonin 5-HT7 receptor agonist LP-44 microinjected into the dorsal raphe nucleus suppresses REM sleep in the rat

(2008) Jaime M. Monti et al.   BEHAVIOURAL BRAIN RESEARCH

Neural circuits subserving behavioral flexibility and their relevance to schizophrenia

(2008) Stan B. Floresco et al.   BEHAVIOURAL BRAIN RESEARCH

Serotonin Receptors

(2008) David E. Nichols et al.   CHEMICAL REVIEWS

5-HT7 receptor stimulation by 8-OH-DPAT counteracts the impairing effect of 5-HT1A receptor stimulation on contextual learning in mice

(2008) Therese M. Eriksson et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Structural Modifications ofN-(1,2,3,4-Tetrahydronaphthalen-1-yl)-4-Aryl-1-piperazinehexanamides: Influence on Lipophilicity and 5-HT7Receptor Activity. Part III

(2008) Marcello Leopoldo et al.   JOURNAL OF MEDICINAL CHEMISTRY

Signaling at G-protein-coupled serotonin receptors: recent advances and future research directions

(2008) M MILLAN et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Further studies in the developmental hyperserotonemia model (DHS) of autism: Social, behavioral and peptide changes

(2007) Ilan M. McNamara et al.   BRAIN RESEARCH

5-HT excites globus pallidus neurons by multiple receptor mechanisms

(2007) L. Chen et al.   NEUROSCIENCE