Sarcopenic Obesity and Endocrinal Adaptation with Age

Sarcopenia, obesity, and natural killer cell immune senescence in aging: Altered cytokine levels as a common mechanism

(2016) Charles T. Lutz et al.   Aging-US

Mononuclear Phagocyte-Derived IL-10 Suppresses the Innate IL-12/IFN-  Axis in Lung-Challenged Aged Mice

(2014) B.-C. Chiu et al.   JOURNAL OF IMMUNOLOGY

Aging is associated with circulating cytokine dysregulation

(2012) Lorena Álvarez-Rodríguez et al.   CELLULAR IMMUNOLOGY

Endothelial function and the regulation of muscle protein anabolism in older adults

(2012) K.L. Timmerman et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Sarcopenia and cachexia: the adaptations of negative regulators of skeletal muscle mass

(2012) Kunihiro Sakuma et al.   Journal of Cachexia Sarcopenia and Muscle

Inflammation and mortality in a frail mouse model

(2011) Fred Ko et al.   AGE

Obesity and weight management in the elderly

(2011) T. S. Han et al.   BRITISH MEDICAL BULLETIN

Physiopathological Mechanism of Sarcopenia

(2011) Stéphane Walrand et al.   CLINICS IN GERIATRIC MEDICINE

Development of Insulin Resistance During Aging: Involvement of Central Processes and Role of Adipokines

(2011) Jose M. Carrascosa et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Interleukin-15 treatment improves glucose homeostasis and insulin sensitivity in obese mice

(2011) N. G. Barra et al.   DIABETES OBESITY & METABOLISM

Reversal of type 2 diabetes: normalisation of beta cell function in association with decreased pancreas and liver triacylglycerol

(2011) E. L. Lim et al.   DIABETOLOGIA

Upregulation of circulating IL-15 by treadmill running in healthy individuals: Is IL-15 an endocrine mediator of the beneficial effects of endurance exercise?

(2011) Yoshiaki Tamura et al.   ENDOCRINE JOURNAL

IL-10 Restricts Activation-Induced Death of NK Cells during Acute Murine Cytomegalovirus Infection

(2011) M. A. Stacey et al.   JOURNAL OF IMMUNOLOGY

Altered Growth Hormone, Cortisol, and Leptin Secretion in Healthy Elderly Persons With Sarcopenia and Mixed Body Composition Phenotypes

(2011) D. L. Waters et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Expression and Function of Myostatin in Obesity, Diabetes, and Exercise Adaptation

(2011) DAVID L. ALLEN et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Metabolic benefits of resistance training and fast glycolytic skeletal muscle

(2010) Nathan K. LeBrasseur et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The depletion of skeletal muscle satellite cells with age is concomitant with reduced capacity of single progenitors to produce reserve progeny

(2010) Kenneth Day et al.   DEVELOPMENTAL BIOLOGY

Lipocalin-2 Deficiency Attenuates Insulin Resistance Associated With Aging and Obesity

(2010) I. K.M. Law et al.   DIABETES

Antibody-directed myostatin inhibition in 21-mo-old mice reveals novel roles for myostatin signaling in skeletal muscle structure and function

(2010) Kate T. Murphy et al.   FASEB JOURNAL

Oxidative Stress, Molecular Inflammation and Sarcopenia

(2010) Si-Jin Meng et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Prevalence and Trends in Obesity Among US Adults, 1999-2008

(2010) Katherine M. Flegal   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Leptin Rapidly Improves Glucose Homeostasis in Obese Mice by Increasing Hypothalamic Insulin Sensitivity

(2010) C. Koch et al.   JOURNAL OF NEUROSCIENCE

Epidemiology and risk profile of heart failure

(2010) Anh L. Bui et al.   Nature Reviews Cardiology

Association between Obesity and Unintentional Injury in Older Adults

(2010) Danielle R. Bouchard et al.   Obesity Facts

Postnatal PPARδ Activation and Myostatin Inhibition Exert Distinct yet Complimentary Effects on the Metabolic Profile of Obese Insulin-Resistant Mice

(2010) Barbara L. Bernardo et al.   PLoS One

Association of C-reactive protein and muscle strength in the English Longitudinal Study of Ageing

(2009) Mark Hamer et al.   AGE

Effects of Exercise Modality on Insulin Resistance and Functional Limitation in Older Adults

(2009) Lance E. Davidson et al.   ARCHIVES OF INTERNAL MEDICINE

Obesity and Aging

(2009) John Harrington et al.   CLINICS IN CHEST MEDICINE

Individualizing recommendations for weight management in the elderly

(2009) Diane Chau et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Supraphysiological hyperinsulinaemia is necessary to stimulate skeletal muscle protein anabolism in older adults: evidence of a true age-related insulin resistance of muscle protein metabolism

(2009) S. Fujita et al.   DIABETOLOGIA

Serum and muscle interleukin-15 levels decrease in aging mice: Correlation with declines in soluble interleukin-15 receptor alpha expression

(2009) LeBris S. Quinn et al.   EXPERIMENTAL GERONTOLOGY

The effects of a soluble activin type IIB receptor on obesity and insulin sensitivity

(2009) I Akpan et al.   INTERNATIONAL JOURNAL OF OBESITY

Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans

(2009) Ethan J. Anderson et al.   JOURNAL OF CLINICAL INVESTIGATION

Increased adipose tissue expression of lipocalin-2 in obesity is related to inflammation and matrix metalloproteinase-2 and metalloproteinase-9 activities in humans

(2009) V. Catalán et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Reduction of low grade inflammation restores blunting of postprandial muscle anabolism and limits sarcopenia in old rats

(2009) Isabelle Rieu et al.   JOURNAL OF PHYSIOLOGY-LONDON

The diseasome of physical inactivity - and the role of myokines in muscle-fat cross talk

(2009) Bente K. Pedersen   JOURNAL OF PHYSIOLOGY-LONDON

Higher Inflammatory Marker Levels in Older Persons: Associations With 5-Year Change in Muscle Mass and Muscle Strength

(2009) L. A. Schaap et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Myostatin Inhibition Enhances the Effects of Exercise on Performance and Metabolic Outcomes in Aged Mice

(2009) N. K. LeBrasseur et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Skeletal Muscle Hypertrophy Following Resistance Training Is Accompanied by a Fiber Type-Specific Increase in Satellite Cell Content in Elderly Men

(2009) L. B. Verdijk et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Changes in IL-15 expression and death-receptor apoptotic signaling in rat gastrocnemius muscle with aging and life-long calorie restriction

(2009) Emanuele Marzetti et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Interleukin-15 Contributes to the Regulation of Murine Adipose Tissue and Human Adipocytes

(2009) Nicole G. Barra et al.   Obesity

Increased muscle PGC-1  expression protects from sarcopenia and metabolic disease during aging

(2009) T. Wenz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular inflammation: Underpinnings of aging and age-related diseases

(2008) Hae Young Chung et al.   AGEING RESEARCH REVIEWS

Cellular and molecular mechanisms underlying age-related skeletal muscle wasting and weakness

(2008) James G. Ryall et al.   BIOGERONTOLOGY

Dietary protein recommendations and the prevention of sarcopenia

(2008) Douglas Paddon-Jones et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Free fatty acids and skeletal muscle insulin resistance

(2008) Edward W Kraegen et al.   CURRENT OPINION IN LIPIDOLOGY

Adipose Tissue: The New Endocrine Organ? A Review Article

(2008) Susan E. Wozniak et al.   DIGESTIVE DISEASES AND SCIENCES

The aging population – Is there a role for endocrine interventions?

(2008) Ralf Nass et al.   GROWTH HORMONE & IGF RESEARCH

Association between Interleukin-15 and Obesity: Interleukin-15 as a Potential Regulator of Fat Mass

(2008) Anders Rinnov Nielsen et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

IL-15Rα chaperones IL-15 to stable dendritic cell membrane complexes that activate NK cells via trans presentation

(2008) Erwan Mortier et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Serum Total and Bioavailable Testosterone Levels, Central Obesity, and Muscle Strength Changes with Aging in Healthy Chinese Men

(2008) Leung-Wing Chu et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Chronic Pain and Obesity in Elderly People: Results from the Einstein Aging Study

(2008) Lucas H. McCarthy et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Modulation of GH/IGF-1 axis: Potential strategies to counteract sarcopenia in older adults

(2008) Silvia Giovannini et al.   MECHANISMS OF AGEING AND DEVELOPMENT

The Role of Lipocalin 2 in the Regulation of Inflammation in Adipocytes and Macrophages

(2008) Jinhui Zhang et al.   MOLECULAR ENDOCRINOLOGY

HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1α

(2008) Zoltan Arany et al.   NATURE

Sarcopenic obesity: A new category of obesity in the elderly

(2008) Mauro Zamboni et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Metabolic Syndrome Is Associated With Silent Ischemic Brain Lesions

(2008) Hirokazu Bokura et al.   STROKE

Leucine-enriched essential amino acid and carbohydrate ingestion following resistance exercise enhances mTOR signaling and protein synthesis in human muscle

(2007) Hans C. Dreyer et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM