Amino acid-accepting ketosynthase domain from a trans-AT polyketide synthase exhibits high selectivity for predicted intermediate

Substrate Specificity in Ketosynthase Domains fromtrans-AT Polyketide Synthases

(2012) Matthew Jenner et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Reprogramming a module of the 6-deoxyerythronolide B synthase for iterative chain elongation

(2012) S. Kapur et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Assessing Oxazole Bioisosteres as Mutasynthons on the Rhizoxin Assembly Line

(2011) Björn Kusebauch et al.   CHEMBIOCHEM

Stereoselective Synthesis of Deuterated β-Cyclohexenylserine, a Biosynthetic Intermediate of the Salinosporamides§

(2011) Jan Deska et al.   ORGANIC LETTERS

Genome Mining Reveals trans-AT Polyketide Synthase Directed Antibiotic Biosynthesis in the Bacterial Phylum Bacteroidetes

(2010) Roberta Teta  et al.   CHEMBIOCHEM

Biosynthesis of polyketides by trans-AT polyketide synthases

(2010) Jörn Piel   NATURAL PRODUCT REPORTS

The Biosynthetic Logic of Polyketide Diversity

(2009) Christian Hertweck   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

PKS and NRPS release mechanisms

(2009) Liangcheng Du et al.   NATURAL PRODUCT REPORTS

Protein–Protein Interactions in Multienzyme Megasynthetases

(2008) Kira J. Weissman et al.   CHEMBIOCHEM

Exploiting the mosaic structure of trans-acyltransferase polyketide synthases for natural product discovery and pathway dissection

(2008) TuAnh Nguyen et al.   NATURE BIOTECHNOLOGY

A ketoreductase domain in the PksJ protein of the bacillaene assembly line carries out both  - and  -ketone reduction during chain growth

(2008) C. T. Calderone et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA