A genome-wide association study follow-up suggests a possible role for PPARG in systemic sclerosis susceptibility

Genetics of scleroderma: implications for personalized medicine?

(2013) Shervin Assassi et al.   BMC Medicine

IRF5polymorphism predicts prognosis in patients with systemic sclerosis

(2012) Roozbeh Sharif et al.   ANNALS OF THE RHEUMATIC DISEASES

Confirmation ofTNIP1but notRHOBandPSORS1C1as systemic sclerosis risk factors in a large independent replication study

(2012) Lara Bossini-Castillo et al.   ANNALS OF THE RHEUMATIC DISEASES

Unraveling the genetic component of systemic sclerosis

(2012) José Ezequiel Martín et al.   HUMAN GENETICS

Identification of CSK as a systemic sclerosis genetic risk factor through Genome Wide Association Study follow-up

(2012) Jose-Ezequiel Martin et al.   HUMAN MOLECULAR GENETICS

Association between the Pro12Ala Polymorphism of Peroxisome Proliferator-Activated Receptor Gamma 2 and Inflammatory Bowel Disease: A Meta-Analysis

(2012) Zhi-Feng Zhang et al.   PLoS One

The replication of the association of the rs6832151 within chromosomal band 4p14 with Graves' disease in a Polish Caucasian population

(2012) K. Szymański et al.   TISSUE ANTIGENS

The genetics of systemic lupus erythematosus and implications for targeted therapy

(2011) A. L. Sestak et al.   ANNALS OF THE RHEUMATIC DISEASES

A GWAS follow-up study reveals the association of the IL12RB2 gene with systemic sclerosis in Caucasian populations

(2011) Lara Bossini-Castillo et al.   HUMAN MOLECULAR GENETICS

A genome-wide association study identifies two new risk loci for Graves' disease

(2011)   NATURE GENETICS

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

(2011) Carl A Anderson et al.   NATURE GENETICS

PPAR-γ Ligands Repress TGFβ-Induced Myofibroblast Differentiation by Targeting the PI3K/Akt Pathway: Implications for Therapy of Fibrosis

(2011) Ajit A. Kulkarni et al.   PLoS One

Identification of Novel Genetic Markers Associated with Clinical Phenotypes of Systemic Sclerosis through a Genome-Wide Association Strategy

(2011) Olga Gorlova et al.   PLoS Genetics

Genome-Wide Scan Identifies TNIP1, PSORS1C1, and RHOB as Novel Risk Loci for Systemic Sclerosis

(2011) Yannick Allanore et al.   PLoS Genetics

Role of PPARG gene variants in inflammatory bowel disease

(2010) Jürgen Glas et al.   INFLAMMATORY BOWEL DISEASES

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

(2010) Andre Franke et al.   NATURE GENETICS

Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus

(2010) Timothy R D J Radstake et al.   NATURE GENETICS

PPARγ Downregulation by TGFß in Fibroblast and Impaired Expression and Function in Systemic Sclerosis: A Novel Mechanism for Progressive Fibrogenesis

(2010) Jun Wei et al.   PLoS One

Rosiglitazone Abrogates Bleomycin-Induced Scleroderma and Blocks Profibrotic Responses Through Peroxisome Proliferator-Activated Receptor-γ

(2009) Minghua Wu et al.   AMERICAN JOURNAL OF PATHOLOGY

Validating, augmenting and refining genome-wide association signals

(2009) John P. A. Ioannidis et al.   NATURE REVIEWS GENETICS

Scleroderma

(2009) Armando Gabrielli et al.   NEW ENGLAND JOURNAL OF MEDICINE

Fat and Beyond: The Diverse Biology of PPARγ

(2008) Peter Tontonoz et al.   Annual Review of Biochemistry

Clinical Risk Factors, DNA Variants, and the Development of Type 2 Diabetes

(2008) Valeriya Lyssenko et al.   NEW ENGLAND JOURNAL OF MEDICINE