Immune checkpoint receptors in regulating immune reactivity in rheumatic disease

A Novel Monoclonal Antibody against Human CD80 and its Immune Protection in a Mouse Lupus-like Disease

(2017) Q. Shi et al.   INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

The global burden of rheumatoid arthritis: estimates from the Global Burden of Disease 2010 study

(2014) Marita Cross et al.   ANNALS OF THE RHEUMATIC DISEASES

Differentiation of follicular helper T cells by salivary gland epithelial cells in primary Sjögren's syndrome

(2014) Ya-Zhuo Gong et al.   JOURNAL OF AUTOIMMUNITY

Activated Renal Macrophages Are Markers of Disease Onset and Disease Remission in Lupus Nephritis

(2014) L. Schiffer et al.   JOURNAL OF IMMUNOLOGY

Engineering of a Novel Anti-CD40L Domain Antibody for Treatment of Autoimmune Diseases

(2014) J. H. Xie et al.   JOURNAL OF IMMUNOLOGY

Pathogenesis and prevention of rheumatic disease: focus on preclinical RA and SLE

(2014) Kevin D. Deane et al.   Nature Reviews Rheumatology

OX40L blockade is therapeutic in arthritis, despite promoting osteoclastogenesis

(2014) Emily Gwyer Findlay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Beneficial Effect of Abatacept in Lupus Nephritis May Include Stabilization of β1 Integrin Activation in Podocytes and Treg Cell Repopulation: Comment on the Article by Furie et al

(2014) Jae Il Shin et al.   Arthritis & Rheumatology

Genetic variation inVTCN1(B7-H4) is associated with course of disease in juvenile idiopathic arthritis

(2013) H M Albers et al.   ANNALS OF THE RHEUMATIC DISEASES

CD40L contributes to angiotensin II-induced pro-thrombotic state, vascular inflammation, oxidative stress and endothelial dysfunction

(2013) Michael Hausding et al.   BASIC RESEARCH IN CARDIOLOGY

Autoantibody Induction by DNA-Containing Immune Complexes Requires HMGB1 with the TLR2/MicroRNA-155 Pathway

(2013) Z. Wen et al.   JOURNAL OF IMMUNOLOGY

B7 family checkpoint regulators in immune regulation and disease

(2013) Sabrina Ceeraz et al.   TRENDS IN IMMUNOLOGY

CD40L demethylation in CD4+ T cells from women with rheumatoid arthritis

(2012) J. Liao et al.   CLINICAL IMMUNOLOGY

Increased production of circulating soluble co-stimulatory molecules CTLA-4, CD28 and CD80 in patients with rheumatoid arthritis

(2012) Ju Cao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Immunotherapy earns its spot in the ranks of cancer therapy

(2012) Drew Pardoll et al.   JOURNAL OF EXPERIMENTAL MEDICINE

p38 Mitogen-activated Protein Kinase and Nuclear Factor- B Facilitate CD40-mediated Salivary Epithelial Cell Death

(2012) L. PING et al.   JOURNAL OF RHEUMATOLOGY

Approval on a knife edge

(2012) Michael Eisenstein   NATURE BIOTECHNOLOGY

Local Administration of Soluble CD40:Fc to the Salivary Glands of Non-Obese Diabetic Mice Does Not Ameliorate Autoimmune Inflammation

(2012) Nienke Roescher et al.   PLoS One

Study of Association of CD40-CD154 Gene Polymorphisms with Disease Susceptibility and Cardiovascular Risk in Spanish Rheumatoid Arthritis Patients

(2012) Mercedes García-Bermúdez et al.   PLoS One

Local delivery of AAV2-CTLA4IgG decreases sialadenitis and improves gland function in the C57BL/6.NOD-Aec1Aec2 mouse model of Sjögren's syndrome

(2012) Hongen Yin et al.   ARTHRITIS RESEARCH & THERAPY

Classical to Current Approach for Treatment of Psoriasis: A Review

(2012) Mahfoozur Rahman et al.   Endocrine Metabolic & Immune Disorders-Drug Targets

The expression and distribution of immunomodulatory proteins B7-H1, B7-DC, B7-H3, and B7-H4 in rheumatoid synovium

(2011) Guoning Guo et al.   CLINICAL RHEUMATOLOGY

THERAPEUTIC HOTLINE: Abatacept: our experience of use in two patients with refractory psoriasis and psoriatic arthritis

(2011) MaryD Altmeyer et al.   Dermatologic Therapy

TL1A and DR3, a TNF family ligand-receptor pair that promotes lymphocyte costimulation, mucosal hyperplasia, and autoimmune inflammation

(2011) Françoise Meylan et al.   IMMUNOLOGICAL REVIEWS

The Expression and Anatomical Distribution of BTLA and Its Ligand HVEM in Rheumatoid Synovium

(2011) Yongjun Shang et al.   INFLAMMATION

CTLA-4-Ig Therapy Diminishes the Frequency but Enhances the Function of Treg Cells in Patients with Rheumatoid Arthritis

(2011) Crisol Álvarez-Quiroga et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Baseline Numbers of Circulating CD28-negative T Cells May Predict Clinical Response to Abatacept in Patients with Rheumatoid Arthritis

(2011) MIRKO SCARSI et al.   JOURNAL OF RHEUMATOLOGY

Prolonged expression of CD154 on CD4 T cells from pediatric lupus patients correlates with increased CD154 transcription, increased nuclear factor of activated T cell activity, and glomerulonephritis

(2010) Jay Mehta et al.   ARTHRITIS AND RHEUMATISM

The efficacy and safety of abatacept in patients with non-life-threatening manifestations of systemic lupus erythematosus: Results of a twelve-month, multicenter, exploratory, phase IIb, randomized, double-blind, placebo-controlled trial

(2010) J. T. Merrill et al.   ARTHRITIS AND RHEUMATISM

Abatacept in the treatment of patients with psoriatic arthritis: Results of a six-month, multicenter, randomized, double-blind, placebo-controlled, phase II trial

(2010) Philip Mease et al.   ARTHRITIS AND RHEUMATISM

B7-H1 expression on non-B and non-T cells promotes distinct effects on T- and B-cell responses in autoimmune arthritis

(2010) Keith M. Hamel et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Association of EBF1, FAM167A(C8orf13)-BLK and TNFSF4 gene variants with primary Sjögren's syndrome

(2010) G Nordmark et al.   GENES AND IMMUNITY

B-cell targeted therapies in human autoimmune diseases: an updated perspective

(2010) Michael J. Townsend et al.   IMMUNOLOGICAL REVIEWS

Autoantibody profiles in systemic sclerosis: Predictive value for clinical evaluation and prognosis

(2010) Yasuhito HAMAGUCHI   JOURNAL OF DERMATOLOGY

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

(2010) F. Stephen Hodi et al.   NEW ENGLAND JOURNAL OF MEDICINE

RNAi-mediated CD40-CD154 interruption promotes tolerance in autoimmune arthritis

(2010) Xiufen Zheng et al.   ARTHRITIS RESEARCH & THERAPY

Association of TNFSF4 (OX40L) polymorphisms with susceptibility to systemic sclerosis

(2009) P. Gourh et al.   ANNALS OF THE RHEUMATIC DISEASES

Amphoteric liposomes enable systemic antigen-presenting cell-directed delivery of CD40 antisense and are therapeutically effective in experimental arthritis

(2009) Evangelos Andreakos et al.   ARTHRITIS AND RHEUMATISM

Efficacy and safety of rituximab in moderately-to-severely active systemic lupus erythematosus: The randomized, double-blind, phase ii/iii systemic lupus erythematosus evaluation of rituximab trial

(2009) Joan T. Merrill et al.   ARTHRITIS AND RHEUMATISM

Possible involvement of soluble B7-H4 in T cell-mediated inflammatory immune responses

(2009) Yosuke Kamimura et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Molecular mechanism and function of CD40/CD40L engagement in the immune system

(2009) Raul Elgueta et al.   IMMUNOLOGICAL REVIEWS

The B7 family member B7-H6 is a tumor cell ligand for the activating natural killer cell receptor NKp30 in humans

(2009) Cameron S. Brandt et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Blocking of CD27-CD70 Pathway by Anti-CD70 Antibody Ameliorates Joint Disease in Murine Collagen-Induced Arthritis

(2009) E. Oflazoglu et al.   JOURNAL OF IMMUNOLOGY

Herpesvirus Entry Mediator-Ig Treatment during Immunization Aggravates Rheumatoid Arthritis in the Collagen-Induced Arthritis Model

(2009) M. Pierer et al.   JOURNAL OF IMMUNOLOGY

Increased expression of soluble inducible costimulator ligand (ICOSL) in patients with systemic lupus erythematosus

(2009) M Her et al.   LUPUS

Rituximab in systemic lupus erythematosusA systematic review of off-label use in 188 cases

(2009) M Ramos-Casals et al.   LUPUS

Psoriasis

(2009) Frank O. Nestle et al.   NEW ENGLAND JOURNAL OF MEDICINE

The effects of PDL-Ig on collagen-induced arthritis

(2009) Guohua Wang et al.   RHEUMATOLOGY INTERNATIONAL

Potential Role of Decoy B7-H4 in the Pathogenesis of Rheumatoid Arthritis: A Mouse Model Informed by Clinical Data

(2009) Takeshi Azuma et al.   PLOS MEDICINE

PD-1 and Its Ligands in Tolerance and Immunity

(2008) Mary E. Keir et al.   Annual Review of Immunology

A CD40-CD154 interaction in tissue fibrosis

(2008) Masataka Kawai et al.   ARTHRITIS AND RHEUMATISM

Antifibroblast antibodies in systemic sclerosis induce fibroblasts to produce profibrotic chemokines, with partial exploitation of toll-like receptor 4

(2008) Serena Fineschi et al.   ARTHRITIS AND RHEUMATISM

Development of autoimmune hepatitis-like disease and production of autoantibodies to nuclear antigens in mice lacking B and T lymphocyte attenuator

(2008) Yoshihiro Oya et al.   ARTHRITIS AND RHEUMATISM

Effect of anti-CD134L mAb and CTLA4Ig on ConA-induced proliferation, Th cytokine secretion, and anti-dsDNA antibody production in spleen cells from lupus-prone BXSB mice

(2008) Yan-Bin Zhou et al.   AUTOIMMUNITY

Pulmonary and Thrombotic Manifestations of Systemic Lupus Erythematosus

(2008) Jeffrey J. Swigris et al.   CHEST

Elevated serum levels of soluble CD154 in children with juvenile idiopathic arthritis

(2008) Sampath Prahalad et al.   Pediatric Rheumatology

Defects in CTLA-4 are associated with abnormal regulatory T cell function in rheumatoid arthritis

(2008) F. Flores-Borja et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting the CD134–CD134L interaction using anti-CD134 and/or rhCD134 fusion protein as a possible strategy to prevent lupus nephritis

(2008) Yan-bin Zhou et al.   RHEUMATOLOGY INTERNATIONAL

Distribution and clinical significance of blood dendritic cells in children with juvenile idiopathic arthritis

(2007) E Smolewska et al.   ANNALS OF THE RHEUMATIC DISEASES