The DNA Damage Response Induced by Infection with Human Cytomegalovirus and Other Viruses

Kaposi's Sarcoma-Associated Herpesvirus Induces the ATM and H2AX DNA Damage Response Early during De Novo Infection of Primary Endothelial Cells, Which Play Roles in Latency Establishment

(2013) V. V. Singh et al.   JOURNAL OF VIROLOGY

A Novel DDB2-ATM Feedback Loop Regulates Human Cytomegalovirus Replication

(2013) X. E et al.   JOURNAL OF VIROLOGY

Human Parvovirus B19 Infection Causes Cell Cycle Arrest of Human Erythroid Progenitors at Late S Phase That Favors Viral DNA Replication

(2013) Yong Luo et al.   JOURNAL OF VIROLOGY

Hepatitis C Virus NS2 Protein Inhibits DNA Damage Pathway by Sequestering p53 to the Cytoplasm

(2013) Cintia Bittar et al.   PLoS One

Induction of DNA Damage Signaling upon Rift Valley Fever Virus Infection Results in Cell Cycle Arrest and Increased Viral Replication

(2012) Alan Baer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DNA viruses and the cellular DNA-damage response

(2012) A. S. Turnell et al.   JOURNAL OF GENERAL VIROLOGY

Engagement of the ATR-Dependent DNA Damage Response at the Human Papillomavirus 18 Replication Centers during the Initial Amplification

(2012) T. Reinson et al.   JOURNAL OF VIROLOGY

RNA Interference-Mediated Targeting of Human Cytomegalovirus Immediate-Early or Early Gene Products Inhibits Viral Replication with Differential Effects on Cellular Functions

(2012) X. E et al.   JOURNAL OF VIROLOGY

Human Parvovirus B19 DNA Replication Induces a DNA Damage Response That Is Dispensable for Cell Cycle Arrest at Phase G2/M

(2012) S. Lou et al.   JOURNAL OF VIROLOGY

Herpes Simplex Virus 1 Ubiquitin Ligase ICP0 Interacts with PML Isoform I and Induces Its SUMO-Independent Degradation

(2012) D. Cuchet-Lourenco et al.   JOURNAL OF VIROLOGY

Inhibition of p53 transcriptional activity by human cytomegalovirus UL44

(2012) Yejin Kwon et al.   MICROBIOLOGY AND IMMUNOLOGY

Consensus on the role of human cytomegalovirus in glioblastoma

(2012) K. Dziurzynski et al.   NEURO-ONCOLOGY

p53 Activation following Rift Valley Fever Virus Infection Contributes to Cell Death and Viral Production

(2012) Dana Austin et al.   PLoS One

HTLV-I Tax Increases Genetic Instability by Inducing DNA Double Strand Breaks during DNA Replication and Switching Repair to NHEJ

(2012) Hicham H. Baydoun et al.   PLoS One

Human cytomegalovirus latency alters the cellular secretome, inducing cluster of differentiation (CD)4+ T-cell migration and suppression of effector function

(2012) G. M. Mason et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Decoding Human Cytomegalovirus

(2012) N. Stern-Ginossar et al.   SCIENCE

At a crossroads: human DNA tumor viruses and the host DNA damage response

(2011) Pavel A Nikitin et al.   Future Virology

Herpesvirus telomeric repeats facilitate genomic integration into host telomeres and mobilization of viral DNA during reactivation

(2011) Benedikt B. Kaufer et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Parvovirus B19 Infection of Human Primary Erythroid Progenitor Cells Triggers ATR-Chk1 Signaling, Which Promotes B19 Virus Replication

(2011) Y. Luo et al.   JOURNAL OF VIROLOGY

Proteomic Profiling of the Human Cytomegalovirus UL35 Gene Products Reveals a Role for UL35 in the DNA Repair Response

(2011) J. Salsman et al.   JOURNAL OF VIROLOGY

The Papillomavirus E1 Helicase Activates a Cellular DNA Damage Response in Viral Replication Foci

(2011) N. Sakakibara et al.   JOURNAL OF VIROLOGY

Nuclear Accumulation of the Papillomavirus E1 Helicase Blocks S-Phase Progression and Triggers an ATM-Dependent DNA Damage Response

(2011) A. Fradet-Turcotte et al.   JOURNAL OF VIROLOGY

Human Cytomegalovirus Induces Multiple Means To Combat Reactive Oxygen Species

(2011) C. Tilton et al.   JOURNAL OF VIROLOGY

DNA Damage during G2 Phase Does Not Affect Cell Cycle Progression of the Green Alga Scenedesmus quadricauda

(2011) Monika Hlavová et al.   PLoS One

Herpesviral replication compartments move and coalesce at nuclear speckles to enhance export of viral late mRNA

(2011) L. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Virus manipulation of cell cycle

(2011) R. Nascimento et al.   PROTOPLASMA

An E2F1-Mediated DNA Damage Response Contributes to the Replication of Human Cytomegalovirus

(2011) Xiaofei E et al.   PLoS Pathogens

Extensive Genome-Wide Variability of Human Cytomegalovirus in Congenitally Infected Infants

(2011) Nicholas Renzette et al.   PLoS Pathogens

Genomes in Conflict: Maintaining Genome Integrity During Virus Infection

(2010) Matthew D. Weitzman et al.   Annual Review of Microbiology

Hepatitis C Virus Infection Downregulates the Ligands of the Activating Receptor NKG2D

(2010) Chaoyang Wen et al.   Cellular & Molecular Immunology

HTLV-1 Tax: Linking transformation, DNA damage and apoptotic T-cell death

(2010) Katerina Chlichlia et al.   CHEMICO-BIOLOGICAL INTERACTIONS

The Viral Oncoprotein Tax Sequesters DNA Damage Response Factors by Tethering MDC1 to Chromatin

(2010) S. Mehdi Belgnaoui et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hepatitis C Virus Inhibits DNA Damage Repair through Reactive Oxygen and Nitrogen Species and by Interfering with the ATM-NBS1/Mre11/Rad50 DNA Repair Pathway in Monocytes and Hepatocytes

(2010) K. Machida et al.   JOURNAL OF IMMUNOLOGY

Evidence that herpes simplex virus DNA derived from quiescently infected cellsin vitro, and latently infected cellsin vivo, is physically damaged

(2010) Scott Millhouse et al.   JOURNAL OF NEUROVIROLOGY

Induction of Reactive Oxygen Species by Human T-Cell Leukemia Virus Type 1 Tax Correlates with DNA Damage and Expression of Cellular Senescence Marker

(2010) T. Kinjo et al.   JOURNAL OF VIROLOGY

Multiple DNA Damage Signaling and Repair Pathways Deregulated by Simian Virus 40 Large T Antigen

(2010) S. Boichuk et al.   JOURNAL OF VIROLOGY

Serotype-Specific Inactivation of the Cellular DNA Damage Response during Adenovirus Infection

(2010) N. A. Forrester et al.   JOURNAL OF VIROLOGY

The Adenovirus E1b55K/E4orf6 Complex Induces Degradation of the Bloom Helicase during Infection

(2010) N. I. Orazio et al.   JOURNAL OF VIROLOGY

A Cytoplasmic ATM-TRAF6-cIAP1 Module Links Nuclear DNA Damage Signaling to Ubiquitin-Mediated NF-κB Activation

(2010) Michael Hinz et al.   MOLECULAR CELL

The Effect of DNA-Dependent Protein Kinase on Adeno-Associated Virus Replication

(2010) Young-Kook Choi et al.   PLoS One

ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS

(2010) A. Alexander et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ATM Activation by Oxidative Stress

(2010) Z. Guo et al.   SCIENCE

Neuropathogenesis of Congenital Cytomegalovirus Infection: Disease Mechanisms and Prospects for Intervention

(2009) M. C.-J. Cheeran et al.   CLINICAL MICROBIOLOGY REVIEWS

Kinases that control the cell cycle in response to DNA damage: Chk1, Chk2, and MK2

(2009) H Christian Reinhardt et al.   CURRENT OPINION IN CELL BIOLOGY

Viral manipulation of DNA repair and cell cycle checkpoints

(2009) Mira S. Chaurushiya et al.   DNA REPAIR

Checkpoint mechanisms at the intersection between DNA damage and repair

(2009) Federico Lazzaro et al.   DNA REPAIR

Mislocalization of the MRN complex prevents ATR signaling during adenovirus infection

(2009) Christian T Carson et al.   EMBO JOURNAL

Cyclin-dependent Kinases Phosphorylate the Cytomegalovirus RNA Export Protein pUL69 and Modulate Its Nuclear Localization and Activity

(2009) Sabine Rechter et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adeno-Associated Virus Replication Induces a DNA Damage Response Coordinated by DNA-Dependent Protein Kinase

(2009) R. A. Schwartz et al.   JOURNAL OF VIROLOGY

Characterization of a Novel Golgi Apparatus-Localized Latency Determinant Encoded by Human Cytomegalovirus

(2009) A. Petrucelli et al.   JOURNAL OF VIROLOGY

Temporal Regulation of the Mre11-Rad50-Nbs1 Complex during Adenovirus Infection

(2009) K. A. Karen et al.   JOURNAL OF VIROLOGY

The DNA-damage response in human biology and disease

(2009) Stephen P. Jackson et al.   NATURE

Mechanism of Genomic Instability in Cells Infected with the High-Risk Human Papillomaviruses

(2009) Meelis Kadaja et al.   PLoS Pathogens

Human Papillomaviruses Activate the ATM DNA Damage Pathway for Viral Genome Amplification upon Differentiation

(2009) Cary A. Moody et al.   PLoS Pathogens

Promyelocytic leukemia-nuclear body proteins: herpesvirus enemies, accomplices, or both?

(2008) Ryan T Saffert et al.   Future Virology

HTLV-1 Tax Oncoprotein Subverts the Cellular DNA Damage Response via Binding to DNA-dependent Protein Kinase

(2008) Sarah S. Durkin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human Cytomegalovirus UL97 Kinase Activity Is Required for the Hyperphosphorylation of Retinoblastoma Protein and Inhibits the Formation of Nuclear Aggresomes

(2008) M. N. Prichard et al.   JOURNAL OF VIROLOGY

Differential Requirements of the C Terminus of Nbs1 in Suppressing Adenovirus DNA Replication and Promoting Concatemer Formation

(2008) S. S. Lakdawala et al.   JOURNAL OF VIROLOGY

Ataxia Telangiectasia-Mutated Damage-Signaling Kinase- and Proteasome-Dependent Destruction of Mre11-Rad50-Nbs1 Subunits in Simian Virus 40-Infected Primate Cells

(2008) X. Zhao et al.   JOURNAL OF VIROLOGY

Human T-Cell Leukemia Virus Type 1 Tax Attenuates the ATM-Mediated Cellular DNA Damage Response

(2008) C. Chandhasin et al.   JOURNAL OF VIROLOGY

The DNA Damage Sensors Ataxia-Telangiectasia Mutated Kinase and Checkpoint Kinase 2 Are Required for Hepatitis C Virus RNA Replication

(2008) Y. Ariumi et al.   JOURNAL OF VIROLOGY

Critical Involvement of the ATM-Dependent DNA Damage Response in the Apoptotic Demise of HIV-1-Elicited Syncytia

(2008) Jean-Luc Perfettini et al.   PLoS One

Phosphorylation of Retinoblastoma Protein by Viral Protein with Cyclin-Dependent Kinase Function

(2008) A. J. Hume et al.   SCIENCE

An Oncogene-Induced DNA Damage Model for Cancer Development

(2008) T. D. Halazonetis et al.   SCIENCE

Activation of the Cellular DNA Damage Response in the Absence of DNA Lesions

(2008) E. Soutoglou et al.   SCIENCE