Virus-Vectored Influenza Virus Vaccines

MVA Vectors Expressing Conserved Influenza Proteins Protect Mice against Lethal Challenge with H5N1, H9N2 and H7N1 Viruses

(2014) Annett Hessel et al.   PLoS One

Stability of neuraminidase in inactivated influenza vaccines

(2014) Ishrat Sultana et al.   VACCINE

AAV Vectors Vaccines Against Infectious Diseases

(2014) Karen Nieto et al.   Frontiers in Immunology

Toward a Universal Influenza Virus Vaccine: Prospects and Challenges

(2013) Natalie Pica et al.   Annual Review of Medicine

Broadly neutralizing antibodies against influenza viruses

(2013) Nick S. Laursen et al.   ANTIVIRAL RESEARCH

Antibody Correlates and Predictors of Immunity to Naturally Occurring Influenza in Humans and the Importance of Antibody to the Neuraminidase

(2013) Robert B. Couch et al.   JOURNAL OF INFECTIOUS DISEASES

Molecular Basis for Broad Neuraminidase Immunity: Conserved Epitopes in Seasonal and Pandemic H1N1 as Well as H5N1 Influenza Viruses

(2013) H. Wan et al.   JOURNAL OF VIROLOGY

Single-Dose Vaccination of a Recombinant Parainfluenza Virus 5 Expressing NP from H5N1 Virus Provides Broad Immunity against Influenza A Viruses

(2013) Z. Li et al.   JOURNAL OF VIROLOGY

Broad protection against influenza infection by vectored immunoprophylaxis in mice

(2013) Alejandro B Balazs et al.   NATURE BIOTECHNOLOGY

Broadly Protective Adenovirus-Based Multivalent Vaccines against Highly Pathogenic Avian Influenza Viruses for Pandemic Preparedness

(2013) Sai V. Vemula et al.   PLoS One

Low Seroprevalent Species D Adenovirus Vectors as Influenza Vaccines

(2013) Eric A. Weaver et al.   PLoS One

Intranasal Antibody Gene Transfer in Mice and Ferrets Elicits Broad Protection Against Pandemic Influenza

(2013) M. P. Limberis et al.   Science Translational Medicine

Protective efficacy of Modified Vaccinia virus Ankara in preclinical studies

(2013) Asisa Volz et al.   VACCINE

Cross-protective efficacy of bivalent recombinant baculoviral vaccine against heterologous influenza H5N1 challenge

(2013) Mookkan Prabakaran et al.   VACCINE

Utilizing poxviral vectored vaccines for antibody induction—Progress and prospects

(2013) Simon J. Draper et al.   VACCINE

Preliminary Assessment of the Efficacy of a T-Cell–Based Influenza Vaccine, MVA-NP+M1, in Humans

(2012) Patrick J. Lillie et al.   CLINICAL INFECTIOUS DISEASES

Experimental vaccines against potentially pandemic and highly pathogenic avian influenza viruses

(2012) Alaina J Mooney et al.   Future Virology

Extended Follow-up Confirms Early Vaccine-Enhanced Risk of HIV Acquisition and Demonstrates Waning Effect Over Time Among Participants in a Randomized Trial of Recombinant Adenovirus HIV Vaccine (Step Study)

(2012) A. Duerr et al.   JOURNAL OF INFECTIOUS DISEASES

Recombinant Parainfluenza Virus 5 Expressing Hemagglutinin of Influenza A Virus H5N1 Protected Mice against Lethal Highly Pathogenic Avian Influenza Virus H5N1 Challenge

(2012) Z. Li et al.   JOURNAL OF VIROLOGY

Recombinant Parainfluenza Virus 5 Vaccine Encoding the Influenza Virus Hemagglutinin Protects against H5N1 Highly Pathogenic Avian Influenza Virus Infection following Intranasal or Intramuscular Vaccination of BALB/c Mice

(2012) A. J. Mooney et al.   JOURNAL OF VIROLOGY

Pre-Clinical Evaluation of a Replication-Competent Recombinant Adenovirus Serotype 4 Vaccine Expressing Influenza H5 Hemagglutinin

(2012) Jeff Alexander et al.   PLoS One

Protective Efficacy of Newcastle Disease Virus Expressing Soluble Trimeric Hemagglutinin against Highly Pathogenic H5N1 Influenza in Chickens and Mice

(2012) Lisette A. H. M. Cornelissen et al.   PLoS One

A T Cell-Inducing Influenza Vaccine for the Elderly: Safety and Immunogenicity of MVA-NP+M1 in Adults Aged over 50 Years

(2012) Richard D. Antrobus et al.   PLoS One

Evaluating a Parainfluenza Virus 5-Based Vaccine in a Host with Pre-Existing Immunity against Parainfluenza Virus 5

(2012) Zhenhai Chen et al.   PLoS One

Randomized comparative study of the serum antihemagglutinin and antineuraminidase antibody responses to six licensed trivalent influenza vaccines

(2012) Robert B. Couch et al.   VACCINE

Advances and Future Challenges in Recombinant Adenoviral Vectored H5N1 Influenza Vaccines

(2012) Jianfeng Zhang   Viruses-Basel

Correlates of vaccine protection from influenza and its complications

(2012) Jonathan A. McCullers et al.   Human Vaccines & Immunotherapeutics

Protective immunity elicited by a pseudotyped baculovirus-mediated bivalent H5N1 influenza vaccine

(2011) Qunfeng Wu et al.   ANTIVIRAL RESEARCH

Coexpression of Avian Influenza Virus H5 and N1 by Recombinant Newcastle Disease Virus and the Impact on Immune Response in Chickens

(2011) Kristina Ramp et al.   AVIAN DISEASES

The STEP Study Provides a Hint That Vaccine Induction of the Right CD8+ T Cell Responses Can Facilitate Immune Control of HIV

(2011) M. Altfeld et al.   JOURNAL OF INFECTIOUS DISEASES

Vesicular Stomatitis Virus-Based H5N1 Avian Influenza Vaccines Induce Potent Cross-Clade Neutralizing Antibodies in Rhesus Macaques

(2011) J. A. Schwartz et al.   JOURNAL OF VIROLOGY

Cold-Adapted Influenza and Recombinant Adenovirus Vaccines Induce Cross-Protective Immunity against pH1N1 Challenge in Mice

(2011) Mark R. Soboleski et al.   PLoS One

Reverse micelle-encapsulated recombinant baculovirus as an oral vaccine against H5N1 infection in mice

(2010) Mookkan Prabakaran et al.   ANTIVIRAL RESEARCH

Potent CD8+ T-Cell Immunogenicity in Humans of a Novel Heterosubtypic Influenza A Vaccine, MVA-NP+M1

(2010) T. K. Berthoud et al.   CLINICAL INFECTIOUS DISEASES

Production of adenovirus vectors and their use as a delivery system for influenza vaccines

(2010) Sai V Vemula et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Cross-protective immunity to influenza A viruses

(2010) Suzanne L Epstein et al.   Expert Review of Vaccines

An alphavirus vector overcomes the presence of neutralizing antibodies and elevated numbers of Tregs to induce immune responses in humans with advanced cancer

(2010) Michael A. Morse et al.   JOURNAL OF CLINICAL INVESTIGATION

Successful Vaccination Strategies That Protect Aged Mice from Lethal Challenge from Influenza Virus and Heterologous Severe Acute Respiratory Syndrome Coronavirus

(2010) T. Sheahan et al.   JOURNAL OF VIROLOGY

Potent Vesicular Stomatitis Virus-Based Avian Influenza Vaccines Provide Long-Term Sterilizing Immunity against Heterologous Challenge

(2010) J. A. Schwartz et al.   JOURNAL OF VIROLOGY

Comparative Efficacy of Hemagglutinin, Nucleoprotein, and Matrix 2 Protein Gene-Based Vaccination against H5N1 Influenza in Mouse and Ferret

(2010) Srinivas S. Rao et al.   PLoS One

A Porcine Adenovirus with Low Human Seroprevalence Is a Promising Alternative Vaccine Vector to Human Adenovirus 5 in an H5N1 Virus Disease Model

(2010) Ami Patel et al.   PLoS One

Influenza Virus Vaccine Based on the Conserved Hemagglutinin Stalk Domain

(2010) J. Steel et al.   mBio

Newcastle Disease Virus-Vectored Vaccines Expressing the Hemagglutinin or Neuraminidase Protein of H5N1 Highly Pathogenic Avian Influenza Virus Protect against Virus Challenge in Monkeys

(2009) J. M. DiNapoli et al.   JOURNAL OF VIROLOGY

A New Genetic Vaccine Platform Based on an Adeno-Associated Virus Isolated from a Rhesus Macaque

(2009) J. Lin et al.   JOURNAL OF VIROLOGY

A pseudotype baculovirus-mediated vaccine confers protective immunity against lethal challenge with H5N1 avian influenza virus in mice and chickens

(2009) Qunfeng Wu et al.   MOLECULAR IMMUNOLOGY

Viruses as vaccine vectors for infectious diseases and cancer

(2009) Simon J. Draper et al.   NATURE REVIEWS MICROBIOLOGY

Immunization of Chickens with Newcastle Disease Virus Expressing H5 Hemagglutinin Protects against Highly Pathogenic H5N1 Avian Influenza Viruses

(2009) Baibaswata Nayak et al.   PLoS One

Safety, immunogenicity and efficacy of poxvirus-based vector vaccines expressing the haemagglutinin gene of a highly pathogenic H5N1 avian influenza virus in pigs

(2009) Constantinos S. Kyriakis et al.   VACCINE

Vaccination focusing immunity on conserved antigens protects mice and ferrets against virulent H1N1 and H5N1 influenza A viruses

(2009) Graeme E. Price et al.   VACCINE

Randomized, double-blind, Phase 1 trial of an alphavirus replicon vaccine for cytomegalovirus in CMV seronegative adult volunteers

(2009) David I. Bernstein et al.   VACCINE

A practical influenza neutralization assay to simultaneously quantify hemagglutinin and neuraminidase-inhibiting antibody responses

(2009) Arash Hassantoufighi et al.   VACCINE

Innate Immune Sensing of Modified Vaccinia Virus Ankara (MVA) Is Mediated by TLR2-TLR6, MDA-5 and the NALP3 Inflammasome

(2009) Julie Delaloye et al.   PLoS Pathogens

Gene Therapy Using Adeno-Associated Virus Vectors

(2008) S. Daya et al.   CLINICAL MICROBIOLOGY REVIEWS

Vaccinia virus strain NYVAC induces substantially lower and qualitatively different human antibody responses compared with strains Lister and Dryvax

(2008) C. M. Midgley et al.   JOURNAL OF GENERAL VIROLOGY

Differential CD4+ versus CD8+ T-Cell Responses Elicited by Different Poxvirus-Based Human Immunodeficiency Virus Type 1 Vaccine Candidates Provide Comparable Efficacies in Primates

(2008) P. Mooij et al.   JOURNAL OF VIROLOGY

HIV-1 vaccine-induced immunity in the test-of-concept Step Study: a case–cohort analysis

(2008) M Juliana McElrath et al.   LANCET

Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial

(2008) Susan P Buchbinder et al.   LANCET

Aerosol immunization with NYVAC and MVA vectored vaccines is safe, simple, and immunogenic

(2008) M. Corbett et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The biology of influenza viruses

(2008) Nicole M. Bouvier et al.   VACCINE

Protective immunity against influenza H5N1 virus challenge in mice by intranasal co-administration of baculovirus surface-displayed HA and recombinant CTB as an adjuvant

(2008) Mookkan Prabakaran et al.   VIROLOGY