Potential deleterious role of anti-Neu5Gc antibodies in xenotransplantation

Distribution of Non-Gal Antigens in Pig Cornea

(2014) David Cohen et al.   CORNEA

Polyclonal Antithymocyte Globulin and Cardiovascular Disease in Kidney Transplant Recipients

(2014) D. Ducloux et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

A Human-Specific Mutation Limits Nonhuman Primate Efficacy in Preclinical Xenotransplantation Studies

(2014) Joshua P. Waldman et al.   TRANSPLANTATION

hCTLA4-Ig transgene expression in keratocytes modulates rejection of corneal xenografts in a pig to non-human primate anterior lamellar keratoplasty model

(2014) Bertrand Vabres et al.   XENOTRANSPLANTATION

Bioprosthetic heart valves of the future

(2014) Rizwan A. Manji et al.   XENOTRANSPLANTATION

Human antibodies reactive to NeuGcGM3 ganglioside have cytotoxic antitumor properties

(2013) Nely Rodríguez-Zhurbenko et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Long-Term IgG Response to Porcine Neu5Gc Antigens without Transmission of PERV in Burn Patients Treated with Porcine Skin Xenografts

(2013) L. Scobie et al.   JOURNAL OF IMMUNOLOGY

A lectin microarray study of glycoantigens in neonatal porcine islet-like cell clusters

(2013) Akira Maeda et al.   JOURNAL OF SURGICAL RESEARCH

Missing links in multiple sclerosis etiology. A working connecting hypothesis

(2013) Jean-Paul Soulillou   MEDICAL HYPOTHESES

A Simple Method for Assessment of Human Anti-Neu5Gc Antibodies Applied to Kawasaki Disease

(2013) Vered Padler-Karavani et al.   PLoS One

IgE Production to α-Gal Is Accompanied by Elevated Levels of Specific IgG1 Antibodies and Low Amounts of IgE to Blood Group B

(2013) Theo Rispens et al.   PLoS One

Detection of Hanganutziu-Deicher antigens inO-glycans from pig heart tissues by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

(2013) Hee-Jin Jeong et al.   XENOTRANSPLANTATION

Double knockout pigs deficient in N-glycolylneuraminic acid and Galactose α-1,3-Galactose reduce the humoral barrier to xenotransplantation

(2013) Andrew J. Lutz et al.   XENOTRANSPLANTATION

N-linked glycan profiling of GGTA1/CMAH knockout pigs identifies new potential carbohydrate xenoantigens

(2013) Christopher Burlak et al.   XENOTRANSPLANTATION

First quantification of alpha-Gal epitope in current glutaraldehyde-fixed heart valve bioprostheses

(2013) Filippo Naso et al.   XENOTRANSPLANTATION

Production of biallelic CMP-Neu5Ac hydroxylase knock-out pigs

(2013) Deug-Nam Kwon et al.   Scientific Reports

Antithymocyte globulin treatment for patients with recent-onset type 1 diabetes: 12-month results of a randomised, placebo-controlled, phase 2 trial

(2013) Stephen E Gitelman et al.   Lancet Diabetes & Endocrinology

Carbohydrate antigens

(2012) Shuji Miyagawa et al.   Current Opinion in Organ Transplantation

Link between endocarditis on porcine bioprosthetic valves and allergy to pork

(2012) Maxime Loyens et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Metabolism of Vertebrate Amino Sugars withN-Glycolyl Groups

(2012) Kalyan Banda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Islet Xenotransplantation Using Gal-Deficient Neonatal Donors Improves Engraftment and Function

(2011) P. Thompson et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Biomedical Differences Between Human and Nonhuman Hominids: Potential Roles for Uniquely Human Aspects of Sialic Acid Biology

(2011) Nissi M. Varki et al.   Annual Review of Pathology-Mechanisms of Disease

Controlling coagulation dysregulation in xenotransplantation

(2011) Peter J Cowan et al.   Current Opinion in Organ Transplantation

Pancreatic β-cell failure in obese mice with human-like CMP-Neu5Ac hydroxylase deficiency

(2011) Sarah Kavaler et al.   FASEB JOURNAL

Induced Anti-Non Gal Antibodies in Human Xenograft Recipients

(2011) Uri Galili   TRANSPLANTATION

Xenotransplantation of Galactosyl-Transferase Knockout, CD55, CD59, CD39, and Fucosyl-Transferase Transgenic Pig Kidneys Into Baboons

(2011) S. Le Bas-Bernardet et al.   TRANSPLANTATION PROCEEDINGS

Potential impact of the non-human sialic acid N-glycolylneuraminic acid on transplant rejection risk

(2011) Vered Padler-Karavani et al.   XENOTRANSPLANTATION

Immunological Property of Antibodies against N-Glycolylneuraminic Acid Epitopes in Cytidine Monophospho-N-Acetylneuraminic Acid Hydroxylase-Deficient Mice

(2010) H. Tahara et al.   JOURNAL OF IMMUNOLOGY

Alginate Macroencapsulation of Pig Islets Allows Correction of Streptozotocin-Induced Diabetes in Primates up to 6 Months Without Immunosuppression

(2010) Denis Dufrane et al.   TRANSPLANTATION

Structural characterization of α1,3-galactosyltransferase knockout pig heart and kidney glycolipids and their reactivity with human and baboon antibodies

(2010) Mette Diswall et al.   XENOTRANSPLANTATION

Results of Gal-Knockout Porcine Thymokidney Xenografts

(2009) A. D. Griesemer et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Evidence for a novel human-specific xeno-auto-antibody response against vascular endothelium

(2009) T. Pham et al.   BLOOD

The Innate Immune Response and Activation of Coagulation in α1,3-Galactosyltransferase Gene-Knockout Xenograft Recipients

(2009) Mohamed Ezzelarab et al.   TRANSPLANTATION

Rejection of Cardiac Xenografts Transplanted from α1,3-Galactosyltransferase Gene-Knockout (GalT-KO) Pigs to Baboons

(2008) Y. Hisashi et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Anticarbohydrate Antibody Repertoires in Patients Transplanted with Fetal Pig Islets Revealed by Glycan Arrays

(2008) O. Blixt et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Diversity in specificity, abundance, and composition of anti-Neu5Gc antibodies in normal humans: Potential implications for disease

(2008) V. Padler-Karavani et al.   GLYCOBIOLOGY

Cetuximab-Induced Anaphylaxis and IgE Specific for Galactose-α-1,3-Galactose

(2008) Christine H. Chung et al.   NEW ENGLAND JOURNAL OF MEDICINE

Proteomic identification of non-Gal antibody targets after pig-to-primate cardiac xenotransplantation

(2008) Guerard W. Byrne et al.   XENOTRANSPLANTATION