Comparison of intestinal metabolism of CYP3A substrates between rats and humans: application of portal–systemic concentration difference method

Effect of amlodipine on the pharmacokinetics of tacrolimus in rats

(2013) Ya-nan Zhou et al.   XENOBIOTICA

Species differences in hepatic and intestinal metabolic activities for 43 human cytochrome P450 substrates between humans and rats or dogs

(2013) Haruka Nishimuta et al.   XENOBIOTICA

Quantitative Prediction of Intestinal Glucuronidation of Drugs in Rats Using In Vitro Metabolic Clearance Data

(2011) Takako Furukawa et al.   Drug Metabolism and Pharmacokinetics

In vitroandin vivosmall intestinal metabolism of CYP3A and UGT substrates in preclinical animals species and humans: species differences

(2011) Hiroshi Komura et al.   DRUG METABOLISM REVIEWS

In vitro–in vivo extrapolation of CYP2C8-catalyzed paclitaxel 6α-hydroxylation: effects of albumin on in vitro kinetic parameters and assessment of interindividual variability in predicted clearance

(2011) Nitsupa Wattanachai et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Quantitative Prediction of Intestinal Metabolism in Humans from a Simplified Intestinal Availability Model and Empirical Scaling Factor

(2010) K. Kadono et al.   DRUG METABOLISM AND DISPOSITION

Prediction of Human Intestinal First-Pass Metabolism of 25 CYP3A Substrates from In Vitro Clearance and Permeability Data

(2010) M. Gertz et al.   DRUG METABOLISM AND DISPOSITION

Intestinal glucuronidation metabolism may have a greater impact on oral bioavailability than hepatic glucuronidation metabolism in humans: A study with raloxifene, substrate for UGT1A1, 1A8, 1A9, and 1A10

(2009) Takashi Mizuma   INTERNATIONAL JOURNAL OF PHARMACEUTICS

The "Albumin Effect" and Drug Glucuronidation: Bovine Serum Albumin and Fatty Acid-Free Human Serum Albumin Enhance the Glucuronidation of UDP-Glucuronosyltransferase (UGT) 1A9 Substrates but Not UGT1A1 and UGT1A6 Activities

(2008) A. Rowland et al.   DRUG METABOLISM AND DISPOSITION

The "Albumin Effect" and in Vitro-in Vivo Extrapolation: Sequestration of Long-Chain Unsaturated Fatty Acids Enhances Phenytoin Hydroxylation by Human Liver Microsomal and Recombinant Cytochrome P450 2C9

(2008) A. Rowland et al.   DRUG METABOLISM AND DISPOSITION

Characterization of Cytochrome P450 Protein Expression along the Entire Length of the Intestine of Male and Female Rats

(2008) D. Mitschke et al.   DRUG METABOLISM AND DISPOSITION

EFFECTS OF LIVER FIBROSIS ON VERAPAMIL PHARMACOKINETICS IN RATS

(2007) Man Chen et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY