Article
Cardiac & Cardiovascular Systems
Jill J. F. Belch, Marianne Brodmann, Iris Baumgartner, Christoph J. Binder, Manuela Casula, Christian Heiss, Thomas Kahan, Paolo Parini, Pavel Poredos, Alberico L. Catapano, Lale Tokgozoglu
Summary: Patients with peripheral arterial disease (PAD) are at high risk of cardiovascular events, but effective management of dyslipidaemia and thrombotic factors can reduce this risk and improve walking performance. Adding ezetimibe or PCSK9 inhibitors can further decrease cardiovascular event risk, while dual antiplatelet therapy can prevent cardiovascular events.
Article
Oncology
Zoia Razumova, Nicolo Bizzarri, Andrei Pletnev, Charlampos Theofanakis, Ilker Selcuk, Elzbieta van der Steen-Banasik, Antonio Gonzalez Martin, Jan Persson
Summary: This article provides an overview of the main activities of the 22nd Meeting of the European Society of Gynaecological Oncology, as well as the most important studies presented at the event for the first time.
INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
(2022)
Article
Biochemistry & Molecular Biology
Bjorn-Philipp Diercks, Helene H. Jensen, Silke B. Chalmers, Emily Coode, Michael B. Vaughan, Roya Tadayon, Pablo J. Saez, Felicity M. Davis, Malene Brohus
Summary: The first junior European Calcium Society online meeting aimed to promote junior researchers in the Ca2+ community by showcasing the diversity of Ca2+ physiology through research across scales and Kingdoms. The meeting featured four scientific sessions covering Ca2+ research from molecular detail to whole organisms, actively involving early-career researchers from different career stages and countries.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
(2021)
Article
Nanoscience & Nanotechnology
Wei Wei, Yuanzhu Ma, Xianzhu Zhang, Wenyan Zhou, Hongwei Wu, Jingwei Zhang, Junxin Lin, Chenqi Tang, Youguo Liao, Chenglin Li, Xiaozhao Wang, Xudong Yao, Yi Wen Koh, Wenwen Huang, Hongwei Ouyang
Summary: A biomimetic joint paint was designed for repairing intractable partial-thickness cartilage defects, showing restoration of smooth cartilage surface and preservation of normal glycosaminoglycan content in rabbit and pig models. The treatment functions by prohibiting chondrocyte apoptosis, maintaining chondrocyte phenotype, and preserving glycosaminoglycan content in the defects, illustrating its effectiveness as a revolutionary therapeutics for noncurable partial-thickness cartilage defects.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Review
Surgery
R. Lorenz, G. Arlt, J. Conze, R. Fortelny, J. Gorjanc, A. Koch, J. Morrison, V. Oprea, G. Campanelli
Summary: The Shouldice technique has been the gold standard for inguinal hernia repair for many years, but mesh repair has shown better results in randomized trials. Despite this, there is still interest in tissue repairs, possibly due to fear of mesh-related pain. After a consensus meeting with international hernia surgeons, a clear standard for the Shouldice technique has been proposed.
Article
Infectious Diseases
Chiara Papalini, Giacomo Pucci, Giulia Cenci, Antonella Mencacci, Daniela Francisci, Auro Caraffa, Pierluigi Antinolfi, Maria Bruna Pasticci
Summary: This study aimed to report the clinical and microbiological findings of patients diagnosed with prosthetic joint infection (PJI) in a hospital in Italy and validate these diagnoses using the European Bone and Joint Infection Society three-level diagnostic approach. The study found that staphylococci were the most common microorganisms, with Staphylococcus aureus and coagulase-negative staphylococci being the most common likely PJI etiologies. Logistic regression analysis did not identify any independent predictors of confirmed PJI.
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
(2022)
Review
Gastroenterology & Hepatology
Stephan C. Bischoff, Rocco Barazzoni, Luca Busetto, Marjo Campmans-Kuijpers, Vincenzo Cardinale, Irit Chermesh, Ahad Eshraghian, Haluk Tarik Kani, Wafaa Khannoussi, Laurence Lacaze, Miguel Leon-Sanz, Juan M. Mendive, Michael W. Mueller, Johann Ockenga, Frank Tacke, Anders Thorell, Darija Vranesic Bender, Arved Weimann, Cristina Cuerda
Summary: This guideline offers evidence-based advice on how to care for patients with chronic gastrointestinal diseases and concomitant obesity, an increasingly common constellation in clinical practice.
UNITED EUROPEAN GASTROENTEROLOGY JOURNAL
(2022)
Article
Oncology
Zoia Razumova, Nicolo Bizzarri, Joanna Kacperczyk-Bartnik, Andrei Pletnev, Antonio Gonzalez Martin, Jan Persson
Summary: This report summarizes the State-of-the-Art Virtual Meeting organized by the European Society of Gynaecological Oncology in December 2020, which provided comprehensive updates on the treatment of gynecological cancers. The conference included case presentations, keynote lectures, interactive debates with opinion leaders, scientific reviews on clinical trials in collaboration with ENGOT, and the introduction of new endometrial cancer guidelines.
INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
(2021)
Article
Engineering, Biomedical
Victoria Drapal, Savannah Mosier, Anna Norman, German Berbel, Jennifer L. Robinson, Elizabeth A. Friis
Summary: Hernias are common and often require surgical intervention. The use of synthetic mesh for hernia repair has a high recurrence rate. This study explores the potential of using piezoelectric materials and therapeutic ultrasound to create an electrically active hernia repair mesh for faster healing.
JOURNAL OF BIOMATERIALS APPLICATIONS
(2023)
Article
Multidisciplinary Sciences
Aaron Michael Jensen, Eric Allen Jensen, Edward Duca, Joseph Roche
Summary: The European Researchers' Night is an annual event aimed at engaging the public with research, held in over 400 cities across Europe. A survey conducted across Ireland, Malta, and the UK found higher levels of university qualification among event attendees compared to the national public, indicating unequal participation based on socio-economic status. While there was mixed evidence on the representation of ethnic minorities at the events, it diverged from existing research findings and suggested potential for improved diversity in public engagement events.
Article
Gastroenterology & Hepatology
Mauro Manno, Simona Deiana, Tommaso Gabbani, Matteo Gazzi, Alessandro Pignatti, Enrica Becchi, Laura Ottaviani, Sara Vavassori, Elis Sacchi, Cesare Hassan, Paola Soriani
Summary: After completing the ESGE-ESGENA sedation training program, the rate of adverse events was very low in our institution. The findings support implementation of the program in all digestive endoscopy units and inclusion in the curriculum for physicians and nurses to ensure safe endoscopic procedures.
Article
Cardiac & Cardiovascular Systems
Andrew J. S. Coats, Stefan D. Anker, Andreas Baumbach, Ottavio Alfieri, Ralph Stephan von Bardeleben, Johann Bauersachs, Jeroen J. Bax, Serge Boveda, Jelena Celutkiene, John G. Cleland, Nikolaos Dagres, Thomas Deneke, Dimitrios Farmakis, Gerasimos Filippatos, Joerg Hausleiter, Gerhard Hindricks, Ewa A. Jankowska, Mitja Lainscak, Christoph Leclercq, Lars H. Lund, Theresa McDonagh, Mandeep R. Mehra, Marco Metra, Nathan Mewton, Christian Mueller, Wilfried Mullens, Claudio Muneretto, Jean-Francois Obadia, Piotr Ponikowski, Fabien Praz, Volker Rudolph, Frank Ruschitzka, Alec Vahanian, Stephan Windecker, Jose Luis Zamorano, Thor Edvardsen, Hein Heidbuchel, Petar M. Seferovic, Bernard Prendergast
Summary: Secondary mitral regurgitation is common in chronic heart failure patients, worsening symptoms and prognosis. Management is complex and requires multidisciplinary Heart Team collaboration for optimization of pharmacological and device therapy according to guideline recommendations.
EUROPEAN HEART JOURNAL
(2021)
Article
Orthopedics
Ricardo Sousa, Ana Ribau, Pedro Alfaro, Marc-Antoine Burch, Joris Ploegmakers, Martin Mcnally, Martin Clauss, Marjan Wouthuyzen-Bakker, Alex Soriano
Summary: This study evaluated the diagnostic accuracy of the newly proposed definition of periprosthetic joint infection (PJI) by the European Bone and Joint Infection Society (EBJIS), comparing it with previous definitions and assessing its accuracy in preoperative diagnosis. The results showed that the EBJIS definition was the most sensitive and accurate in ruling out infection preoperatively.
Article
Nanoscience & Nanotechnology
Wen Li, Shijun Shu, Aref Nooraei, Erfan Abadifard, Mustafa D. Younus, Hongwei Gao
Summary: This study explored the effect of PVA/n-HA/P66 on repairing traumatic cartilage defects in rabbit knee joint. The results showed that PVA/n-HA/P66 increased the expression of type II collagen and had a high effectiveness in treating cartilage defects.
JOURNAL OF BIOMEDICAL NANOTECHNOLOGY
(2022)
Review
Oncology
Laura Biganzoli, Nicole Matteo Luca Battisti, Hans Wildiers, Amelia McCartney, Giuseppe Colloca, Ian H. Kunkler, Maria-Joao Cardoso, Kwok-Leung Cheung, Nienke Aafke de Glas, Rubina M. Trimboli, Beatriz Korc-Grodzicki, Enrique Soto-Perez-de-Celis, Antonio Ponti, Janice Tsang, Lorenza Marotti, Karen Benn, Matti S. Aapro, Etienne G. C. Brain
Summary: Breast cancer in older adults is becoming more common and challenging to manage due to its heterogeneity and lack of specific evidence. An expert taskforce expanded and updated guidelines with endorsement from the European Cancer Organisation, including factors like chemotherapy toxicity prediction, cultural and social considerations, and genetic screening. Age should not be the sole factor in decision-making, with careful consideration of geriatric assessments, life expectancy, and patient preferences.
